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Clinical Progression of Giant-Axonal Neuropathy over a Twelve Year Period

Published online by Cambridge University Press:  18 September 2015

Joseph M. Dooley ,
Yasufumi Oshima ,
Laurence E. Becker  and
E. Gordon Murphy
Joseph M. Dooley
Affiliation:
Division of Neurology (Department of Paediatrics) and Department of Pathology, The Hospital for Sick Children, Toronto, Canada
Yasufumi Oshima
Affiliation:
Division of Neurology (Department of Paediatrics) and Department of Pathology, The Hospital for Sick Children, Toronto, Canada
Laurence E. Becker*
Affiliation:
Division of Neurology (Department of Paediatrics) and Department of Pathology, The Hospital for Sick Children, Toronto, Canada
E. Gordon Murphy
Affiliation:
Division of Neurology (Department of Paediatrics) and Department of Pathology, The Hospital for Sick Children, Toronto, Canada
*
Department of Pathology, The Hospital for Sick Children, 555 University Avenue, Toronto, Canada. M5G 1X8
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Abstract:

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Giant-axonal neuropathy (GAN), a chronic peripheral neuropathy with associated Central Nervous System dysfunction and tight curly hair, is described in a 17-year-old girl. Biopsies of this girl’s muscle and nerve are characteristic of this condition. Her clinical course over a 12 year period characterizes a disease of a slowly progressive nature.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 8 , Issue 4 , November 1981 , pp. 321 - 323
Copyright
Copyright © Canadian Neurological Sciences Federation 1981

References

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