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Concurrence of glioma and multiple sclerosis

Published online by Cambridge University Press:  02 December 2014

Shah-Naz Hayat Khan ,
Joseph E. Buwembo  and
Q. Li
Shah-Naz Hayat Khan*
Affiliation:
Division of Neurosurgery, Department of Surgery, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
Joseph E. Buwembo
Affiliation:
Section of Neurosurgery, Department of Surgery, Regina General Hospital, Regina, Saskatchewan, Canada
Q. Li
Affiliation:
Department of Pathology, Regina General Hospital, Regina, Saskatchewan, Canada
*
Division of Neurosurgery, Department of Surgery, 103 Hospital Drive, Royal University Hospital, Saskatoon, Saskatchewan, S7N 0W8, Canada
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A 29-year-old Caucasian female diagnosed with multiple sclerosis (MS) for seven years, presented with a history of headaches and a single episode of new onset seizures. Her physical examination was unremarkable and she was placed on anti-seizure medications. A computed tomography (CT) scan showed a right frontal brain lesion causing minimal mass effect (Figure 1). Magnetic resonance imaging (MRI) revealed a large nonenhancing space occupying lesion in the right frontal lobe, in addition to numerous smaller lesions which were characteristic of MS plaques (Figures 2 & 3). The large lesion was causing mass effect with right to left midline shift (Figures 2, 3A & B). Given the patient’s history, the appearance and unusually large size of the frontal lesion, it was unclear whether it was a demyelinating MS plaque, or an intra-axial tumour.

Type
Neuroimaging Highlight
Information
Canadian Journal of Neurological Sciences , Volume 32 , Issue 3 , August 2005 , pp. 349 - 351
Copyright
Copyright © The Canadian Journal of Neurological 2005

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