Hostname: page-component-cd9895bd7-gvvz8 Total loading time: 0 Render date: 2024-12-27T09:43:08.836Z Has data issue: false hasContentIssue false
  • English
  • Français

Development of Surgical Therapy of Epilepsy at the Montreal Neurological Institute

Published online by Cambridge University Press:  18 September 2015

William Feindel
William Feindel*
Affiliation:
Montreal Neurological Institute and hospital, Department of Neurology and Neurosurgery, McGill University, Montreal
*
Montreal Neurological Institute, Suite 110, 3801 University Street, Montreal, Quebec, Canada H3B 2B4
Rights & Permissions [Opens in a new window]

Abstract:

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Wilder Penfield's development of surgical methods for treating focal cerebral seizures, beginning with his early work in Montreal in 1928, is reviewed. The reliance on seizure pattern and focal brain pathology was enormously enhanced by the advent of EEG and direct electrical recording from the cortex during surgery. The recognition in the early 1950's of mesial temporal structures in the pathogenesis of temporal lobe epilepsy with automatism lead to more rational and successful surgical treatment. Positron emission tomography and especially magnetic resonance imaging have recently added to the essential diagnostic information of focal epilepsy provided by EEG.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 18 , Issue S4 , November 1991 , pp. 549 - 553
Copyright
Copyright © Canadian Neurological Sciences Federation 1991

References

REFERENCES

1.Foerster, O, Penfield, W. The structural basis of traumatic epilepsy and results of radical operation. Brain 1930; 53(11): 99–119.CrossRefGoogle Scholar
2.Report of the Neurosurgical Service, Royal Victoria Hospital. 1930; Penfield Archive.Google Scholar
3.Penfield, W, ed. Cytology and cellular pathology of the nervous system. (3 vols., 1267 pages) New York: Paul B. Hoeber, Inc., 1932.Google Scholar
4.Penfield, W. The evidence for a cerebral vascular mechanism in epilepsy. Ann Intern Med Assoc 1933; 7(3): 303–310.Google Scholar
5.Penfield, W. The circulation of the epileptic brain. Res Pubi Assoc Res Nerv Ment Dis 1937; 18: 605–637.Google Scholar
6.Penfield, W. Remarks on incomplete hypothesis for the control of cerebral circulation. J Neurosurg 1971; 35: 124–127.CrossRefGoogle Scholar
7.Penfield, W. Boldrey, E. Somatic motor and sensory representation in the cerebral cortex of man as studied by electrical stimulation. Brain 1937; 60(4): 389–443.CrossRefGoogle Scholar
8.Penfield, W, Erickson, TC. Epilepsy and cerebral localization (632 pages). Springfield, I11.: Charles C. Thomas, 1941.Google Scholar
9.Penfield, W, Kristiansen, K. Epileptic seizure patterns (104 pages). Springfield, I11.: P. Charles C. Thomas; Oxford, England: Blackwell, 1951.Google Scholar
10.Penfield, W, Rasmussen, T. The cerebral cortex of man (468 pages). New York: The Macmillan Company, 1951.Google Scholar
11.Penfield, W, Earle, KM, Baldwin, M. Incisural sclerosis and temporal lobe seizures produced by hippocampal herniation at birth. Arch Neurol Psychiatry 1953; 69: 17–42.Google Scholar
12.Feindel, W, Penfield, W, Jasper, H. Localization of epileptic discharge in temporal lobe automatism. Trans Am Neurol Assoc 1952; 14–17.Google ScholarPubMed
13.Feindel, W, Penfield, W. Localization of epileptic discharge in temporal lobe automatism. Arch Neurol Psychiatry 1954; 72: 605–630.CrossRefGoogle ScholarPubMed
14.Feindel, W, Rasmussen, T. Temporal lobectomy with amygdalectomy and minimal hippocampal resection: review of 100 cases, (this supplement)Google Scholar
15.Penfield, W, Baldwin, M. Temporal lobe seizures and the technic of subtotal temporal lobectomy. Ann Surg 1952; 136(4): 625–634.Google ScholarPubMed
16.Penfield, W, Jasper, H. Epilepsy and the functional anatomy of the human brain (896 pages). Boston: Little, Brown and Company, 1954.Google Scholar
17. Penfield, W, Milner, B. Memory deficit produced by bilateral lesions in the hippocampal zone. Arch Neurol Psychiatry 1958; 79: 475–497.CrossRefGoogle ScholarPubMed
18.Penfield, W, Roberts, L. Speech and brain-mechanisms (286 pages). Princeton: Princeton University Press, 1959.Google Scholar
19.Feindel, W, Gloor, P, Yamamoto, YL, et al. Correlation of EEG and topographic cerebral blood flow in epilepsy by positron emission tomography. In: Akimoto, H, Kazamatsuri, H, Seino, M, Ward, AA Jr., eds. Advances in Epileptology: XIII Epilepsy International Symposium. New York: Raven Press, 1982: 151–156.Google Scholar
20.Yamamoto, YL, Ochs, R, Gloor, P, et al. Patterns of rCBF and focal energy metabolic changes in relation to electroencephalographic abnormality in the inter-ictal phase of partial epilepsy. In: Baldy-Moulinier, M, Ingvar, DH, Meldrum BS, eds. Cerebral Flood Flow, Metabolism and Epilepsy. 1. Current Problems in Epilepsy. London: John Libbey, 1983; 51–62.Google Scholar
21.Yamamoto, YL, Ochs, R, Ammann, W, et al. Changes of energy metabolism and regional cerebral blood flow studied by positron emission tomography in the interjetai phase of partial epilepsy. Acta Neurochir 1984; Suppl 33: 35–46.Google Scholar
22.Gloor, P, Olivier, A, Quesney, LF, et al. The role of the limbic system in experiential phenomena of temporal lobe epilepsy. Ann Neurol 1982; 12: 129–144.CrossRefGoogle ScholarPubMed
23.Kuzniecky, R, de la Sayette, V, Ethier, R, et al. Magnetic resonance imaging in temporal lobe epilepsy: pathology correlations. Ann Neurol 1987; 22: 341–347.CrossRefGoogle Scholar
24.Feindel, W, Robitaille, Y, Tampieri, D, et al. EEG, MRI and pathology in patients treated surgically for temporal lobe epilepsy, (this supplement)Google Scholar