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The Effect of tPA on Inpatient Rehabilitation after Stroke: A Cost Comparison

Published online by Cambridge University Press:  20 October 2014

Marina Richardson ,
Matthew Meyer  and
Robert Teasell
Marina Richardson*
Affiliation:
Lawson Health Research Institute
Matthew Meyer
Affiliation:
Lawson Health Research Institute Department of Epidemiology and Biostatistics, Western University
Robert Teasell
Affiliation:
Lawson Health Research Institute Department of Physical Medicine and Rehabilitation, Western University St. Joseph’s Health Care London, Parkwood Hospital, London, Ontario, Canada
*
Parkwood Hospital - B3019, 801 Commissioners Road East, London, Ontario, N6C 5J1, Canada. Email: Marina.Richardson@sjhc.london.on.ca.
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Abstract

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Background:

Tissue plasminogen activator has been found to significantly improve patient outcomes post stroke. Previous economic evaluations have adjusted for fewer admissions to inpatient rehabilitation but not for decreased length of stay in rehabilitation. Our objective was to estimate the potential cost savings associated with a decreased length of stay in inpatient rehabilitation for patients who receive tissue plasminogen activator compared to those who do not, in a Canadian context.

Methods:

Decreased length of stay in inpatient rehabilitation for patients who received tissue plasminogen activator compared to controls was reported previously in a population of 1962 patients admitted to hospital with an ischemic stroke in Ontario between July 1, 2003 and March 31, 2008. Average per diem cost savings associated with the use of tissue plasminogen activator were calculated using a literature based cost estimate. Sensitivity analysis varying the length of stay in inpatient rehabilitation was performed.

Results:

The estimated mean per diem cost of inpatient rehabilitation derived from the literature was $626. Based on previously reported estimates for reduced length of stay, receipt of tissue plasminogen activator was estimated to result in savings of $939 per patient during inpatient rehabilitation. Sensitivity analysis suggested that these cost savings could range from $501 to $1377 per patient on average.

Conclusions:

Future economic evaluations of tissue plasminogen activator should consider adjusting for shortened length of stay in inpatient rehabilitation for patients who receive tissue plasminogen activator.

Type
Original Article
Information
Canadian Journal of Neurological Sciences , Volume 41 , Issue 4 , July 2014 , pp. 482 - 485
Copyright
Copyright © The Canadian Journal of Neurological 2014

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