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Functional Implications of Changes in the Senescent Brain: A Review

Published online by Cambridge University Press:  18 September 2015

Charles H.M. Beck
Charles H.M. Beck*
Affiliation:
Neuropsychology Unit, Department of Psychology, University of Alberta, Edmonton, Alberta
*
Department of Physiology, Biological Sciences Building, University of Alberta, Edmonton, Alberta, T6G 2E9, Canada.
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The morphological, chemical, and physiological changes in the brain accompanying old age are reviewed. The deterioration of the striatal and hypothalamic dopaminergic systems were implicated in the onset of age related Parkinsonian-like slowing of performance and altered affect. Cholinergic hippocampal and neocortical systems were chemically and physiologically abnormal in the aged. The implications for slowed cognitive processing and persistance of the memory trace are presented.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 5 , Issue 4 , November 1978 , pp. 417 - 424
Copyright
Copyright © Canadian Neurological Sciences Federation 1978

References

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