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The Incidence Trends of Primary Brain Tumors in Saskatchewan from 1970 to 2001

Published online by Cambridge University Press:  02 December 2014

F. Pirouzmand  and
V. Sadanand
F. Pirouzmand
Affiliation:
Division of Neurosurgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON
V. Sadanand
Affiliation:
Division of Neurosurgery, Royal University Hospital, Saskatoon, SK, Canada
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Abstract

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Objective:

There has been a paucity of information on the epidemiology of primary brain tumors (BTs) in Canada. This study documents epidemiology of primary BTs in Saskatchewan over three decades to define their current state, changing pattern over years and relative distribution in two geographically defined areas of the province.

Methods:

Data on all primary BTs from 1970 to 2001 from the Brain Tumor Registry in Saskatchewan was collected. The aggregate data on primary BTs including the time-series for incidence, age, geographic location and sex were statistically analyzed using SPSS 13. Poisson regression was used to model the incidence as a function of decade of diagnosis and age at the time of diagnosis.

Results:

The average annual incidence of primary BTs was 11.1 per 100,000 person-years (male 12.5 per 100.000 and female 9.8 per 100.000). Males constituted 54.5% of all these tumors. The age distribution of tumors was bimodal with peaks at 5 years and 65 years. During this time, the incidence of primary BTs has increase predominantly in non-malignant types. No difference was found in the rate of all the diagnosed primary BTs combined, meningioma and lymphoma between the northern part (Regina) and southern part (Saskatoon) of the province.

Conclusions:

The incidence of BTs in Saskatchewan is more than previously reported in Canada. There is a temporal trend in increasing incidence of some of the BTs predominantly in the non-malignant types. No spatial difference in the incidence of primary BTs was shown in this province. These data will provide useful information to guide the future studies on BTs changing patterns, possible etiologies and efficient resource allocation for management of these diseases.

Résumé:

RÉSUMÉ:Objectif :

Il y a peu d'information sur l'épidémiologie des tumeurs primitives du cerveau (TCs) au Canada. Cette étude fait état de l'épidémiologie des TCs primitives en Saskatchewan pendant trois décennies afin de décrire la situation actuelle, les changements dans le temps et la distribution relative dans deux régions de la province qui sont bien définies au point de vue géographique.

Méthodes :

Nous avons extrait les données contenues dans le registre des tumeurs cérébrales de la Saskatchewan concernant toutes les TCs primaires de 1970 à 2001. Nous avons analysé l'agrégat de données sur les TCs primaires, dont les séries temporelles pour l'incidence, l'âge, le lieu géographique et le sexe au moyen du SPSS 13. Nous avons utilisé la régression de Poisson pour modéliser l'incidence comme fonction de la décade du diagnostic et de l'âge au moment du diagnostic.

Résultats :

L'incidence annuelle moyenne des TCs était de 11,1 par 100 000 personnes-années (12,5 par 100 000 pour les hommes et 9,8 par 100 000 pour les femmes). 54% des patients étaient des hommes. La distribution de l'âge était bimodale, avec un pic à 5 ans et un pic à 65 ans. Pendant la période étudiée, l'incidence des TCs a augmenté surtout en ce qui concerne les tumeurs bénignes. Il n'y avait pas de différence dans le taux de toutes les TCs combinées, le méningiome et le lymphome entre la partie nord (Regina) et la partie sud (Saskatoon) de la province.

Conclusions :

L'incidence des TCs en Saskatchewan est plus élevée que celle rapportée antérieurement au Canada. On observe une tendance temporelle à l'augmentation de l'incidence de certaines TCs, surtout des tumeurs bénignes. Aucune différence n'a été observée dans l'incidence des TCs primitives entre les régions de cette province. Ces données pourront servir de guide dans l'élaboration d'études éventuelles sur l'incidence, les étiologies possibles et l'allocation des ressources pour le traitement de ces maladies.

Type
Original Articles
Information
Canadian Journal of Neurological Sciences , Volume 34 , Issue 2 , May 2007 , pp. 181 - 186
Copyright
Copyright © The Canadian Journal of Neurological 2007

References

1. Sutherland, GR, Florell, R, Louw, D, Choi, NW, Sima, AA. Epidemiology of primary intracranial neoplasms in Manitoba, Canada. Can J Neurol Sci. 1987; 14:586-92.Google Scholar
2. Deorah, S, Lynch, CF, Sibenaller, ZA, Ryken, TC. Trends in brain cancer incidence and survival in the United States, SEER program, 1973 to 2001. Neurosurg Focus. 2006; 20:1-7.Google Scholar
3. Elia-Pasquet, S, Provost, D, Jaffre, A, Loiseau, H, Vital, A, Kantor, G, et al. Incidence of central nervous system tumors in Gironde, France. Neuroepidemiology. 2004; 23:110-7.Google Scholar
4. McKinney, PA. Brain tumours: incidence, survival, and aetiology. J Neurol Neurosurg Psychiatry. 2004; 75 Suppl 2:ii12–ii17.Google Scholar
5. Wrensch, M, Minn, Y, Chew, T, Bondy, M, Berger, MS. Epidemiology of primary brain tumors: current concepts and review of the literature. Neuro Oncol. 2002; 4:278-99.Google Scholar
6. American Cancer Society. Manual of tumor nomenclature. New York: American Cancer Society, 1951.Google Scholar
7. World Health Organization. International classification of diseases for oncology. Geneva: World Health Organization; 1976.Google Scholar
8. World Health Organization. International classification of diseases for oncology. Geneva: World Health Organization; 1990.Google Scholar
9. Annegers, JF, Schoenberg, BS, Okazaki, H, Kurland, LT. Epidemiologic study of primary intracranial neoplasms. Arch Neurol. 1981; 38:217-9.Google Scholar
10. Hess, KR, Broglio, KR, Bondy, ML. Adult glioma incidence trends in the United States, 1977-2000. Cancer. 2004; 101:2293-9.Google Scholar
11. Johannesen, TB, Angell-Andersen, E, Tretli, S, Langmark, F, Lote, K. Trends in incidence of brain and central nervous system tumors in Norway, 1970-1999. Neuroepidemiology. 2004; 23:101-9.Google Scholar
12. Jukich, PJ, McCarthy, BJ, Surawicz, TS, Freels, S, Davis, FG. Trends in incidence of primary brain tumors in the United States. 1985-1994. Neuro Oncol. 2001; 3:141-51.CrossRefGoogle ScholarPubMed
13. Kuratsu, J, Ushio, Y. Epidemiological study of primary intracranial tumors: a regional survey in Kumamoto Prefecture in the southern part of Japan. J Neurosurg. 1996; 84:946-50.Google Scholar
14. Surveillance, Epidemiology, and End Results (SEER) program: National Cancer Institute. 2006. Ref Type: Internet Communication. Available at: http://seer.cancer.gov/Google Scholar