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Loss of Purkinje Cells is Associated with Demyelination in Multiple Sclerosis

Published online by Cambridge University Press:  02 December 2014

Fabrizio Giuliani ,
Ingrid Catz ,
Edward Johnson ,
Lothar Resch  and
Kenneth Warren
Fabrizio Giuliani*
Affiliation:
Department of Medicine (Neurology), University of Alberta, Edmonton, Alberta, Canada
Ingrid Catz
Affiliation:
Department of Medicine (Neurology), University of Alberta, Edmonton, Alberta, Canada
Edward Johnson
Affiliation:
Laboratory Medicine and Pathology (Neuropathology), University of Alberta, Edmonton, Alberta, Canada
Lothar Resch
Affiliation:
Laboratory Medicine and Pathology (Neuropathology), University of Alberta, Edmonton, Alberta, Canada
Kenneth Warren
Affiliation:
Department of Medicine (Neurology), University of Alberta, Edmonton, Alberta, Canada
*
Division of Neurology - Department of Medicine, University of Alberta, 9-101 Clinical Sciences Building – University of Alberta, Edmonton, Alberta, T6G 2G3, Canada
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Abstract

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Type
Brief Communications
Information
Canadian Journal of Neurological Sciences , Volume 38 , Issue 3 , May 2011 , pp. 529 - 531
Copyright
Copyright © The Canadian Journal of Neurological 2011

References

1 Rudick, RA, Trapp, BD. Gray-matter injury in multiple sclerosis. N Engl J Med. 2009;361:1505–6.Google Scholar
2 Kutzelnigg, A, Faber-Rod, JC, Bauer, J, et al. Widespread demyelination in the cerebellar cortex of multiple sclerosis. Brain Pathol. 2007;17:38–44.Google Scholar
3 Alusi, SH, Worthington, J, Glickman, S, et al. A study of tremor in multiple sclerosis. Brain. 2001;124:720–30.CrossRefGoogle ScholarPubMed
4 Trapp, BD, Nave, KA. Multiple Sclerosis’ an immune or neurodegenerative disorder? Ann Rev Neurosci. 2006;31:247–69.Google Scholar
5 Giuliani, F, Goodyer, CG, Antel, JP, et al. Vulnerability of human neurons to T cell-mediated cytotoxicity. J Immunol. 2003;171: 368–79.CrossRefGoogle ScholarPubMed