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Multiple Sclerosis Treated with Antithymocyte Globulin — A Five Year Follow-Up

Published online by Cambridge University Press:  18 September 2015

L.F. Kastrukoff ,
D.R. McLean  and
T.A. McPherson
L.F. Kastrukoff
Affiliation:
Department of Medicine, Division of Neurology of the University of Alberta, Edmonton
D.R. McLean*
Affiliation:
Department of Medicine, Division of Neurology of the University of Alberta, Edmonton
T.A. McPherson
Affiliation:
Division of Oncology of the University of Alberta, Edmonton
*
Division of Neurology, Department of Medicine, 9-101 Clinical Sciences Building, University of Alberta, Edmonton, Alberta, Canada T6G 2G3.
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Multiple sclerosis patients treated with antithymocyte globulin (ATG) were re-evaluated after five years. No long term benefit was found. Notably, the group of patients with an elevated gamma globulin to total protein ration in their C.S.F. and who did particularly well after treatment with ATG also failed to show any long term benefit. Few long term detrimental effects of ATG immunosuppression were identified. The implications of the results are discussed as they relate to the use of immunosuppression in multiple sclerosis.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 5 , Issue 2 , May 1978 , pp. 175 - 178
Copyright
Copyright © Canadian Neurological Sciences Federation 1978

References

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