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Neuroleptic-Induced Tardive Cervical Dystonia: Clinical Series of 20 Patients

Published online by Cambridge University Press:  02 December 2014

Clecio Godeiro-Junior ,
Andre C. Felício ,
Patrícia de Carvalho Aguiar ,
Vanderci Borges ,
Sonia M. A. Silva  and
Henrique B. Ferraz
Clecio Godeiro-Junior*
Affiliation:
Department of Neurology and Neurosurgery, Movement Disorders Unit, Federal University of São Paulo, São Paulo, Brazil
Andre C. Felício
Affiliation:
Department of Neurology and Neurosurgery, Movement Disorders Unit, Federal University of São Paulo, São Paulo, Brazil
Patrícia de Carvalho Aguiar
Affiliation:
Department of Neurology and Neurosurgery, Movement Disorders Unit, Federal University of São Paulo, São Paulo, Brazil
Vanderci Borges
Affiliation:
Department of Neurology and Neurosurgery, Movement Disorders Unit, Federal University of São Paulo, São Paulo, Brazil
Sonia M. A. Silva
Affiliation:
Department of Neurology and Neurosurgery, Movement Disorders Unit, Federal University of São Paulo, São Paulo, Brazil
Henrique B. Ferraz
Affiliation:
Department of Neurology and Neurosurgery, Movement Disorders Unit, Federal University of São Paulo, São Paulo, Brazil
*
Rua Dr Diogo de Faria, 650, ap. 33, Vila Clementino, Postal Code 04037-002, SãPaulo, SãPaulo, Brazil
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Abstract

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Background:

Cervical dystonia (CD) may be classified according to the underlying cause into primary or secondary CD. Previous exposure to neuroleptics is one of the main causes of adult-onset secondary dystonia. There are few reports that characterize the clinical features of primary CD and secondary neuroleptic-induced CD. Herein our aim was to investigate a series of patients with neuroleptic induced tardive CD and to describe their clinical and demographic features.

Patients and Methods:

We retrospectively evaluated 20 patients with neuroleptic-induced tardive CD and compared clinical, demographic and therapeutic characteristics to another 77 patients with primary CD. All patients underwent Botulinum toxin type-A therapy.

Results:

We did not identify any relevant clinical and demographic characteristics in our group of patients that could be used to distinguish tardive and primary CD.

Conclusion:

Patients with tardive CD presented demographic characteristics and disease course similar to those with primary CD.

Type
Original Article
Information
Canadian Journal of Neurological Sciences , Volume 36 , Issue 2 , March 2009 , pp. 222 - 226
Copyright
Copyright © The Canadian Journal of Neurological 2009

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