Hostname: page-component-cd9895bd7-mkpzs Total loading time: 0 Render date: 2024-12-27T09:26:05.656Z Has data issue: false hasContentIssue false
  • English
  • Français

Neuropathic Pain: Redundant Pathways, Inadequate Therapy

Published online by Cambridge University Press:  02 December 2014

Douglas Zochodne
Douglas Zochodne*
Affiliation:
Department of Clinical Neurosciences and the Hotchkiss Brain Institute University of Calgary, Calgary, Alberta, Canada
Rights & Permissions [Opens in a new window]

Abstract

An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Editorial
Information
Canadian Journal of Neurological Sciences , Volume 39 , Issue 4 , July 2012 , pp. 409 - 410
Copyright
Copyright © The Canadian Journal of Neurological 2012

References

1.Stemkowski, PL, Smith, PA.Sensory neurons, ion channels, inflammation and the onset of neuropathic pain. Can J Neurol Sci. 2012;39(4):416–35.CrossRefGoogle ScholarPubMed
2.Willis, DE, Twiss, JL.The evolving roles of axonally synthesized proteins in regeneration. Curr Opin Neurobiol. 2006 Feb;16:111–18.CrossRefGoogle ScholarPubMed
3.Zhang, X, Meister, B, Elde, R, Verge, VMK, Hokfelt, T.Large calibre primary afferent neurons projecting to the gracile nucleus express neuropeptide Y after sciatic nerve lesions: an immunohistochemical and in situ hybridization study in rats. Eur J Neurosci. 1993;5:1510–19.CrossRefGoogle Scholar
4.Verge, VMK, Gratto, KA, Karchewski, LA, Richardson, PM.Neurotrophins and nerve injury in the adult. Philos Trans R Soc Lond B Biol Sci. 1996;351:423–30.Google ScholarPubMed
5Coull, JA, Beggs, S, Boudreau, D, et al.BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain. Nature. 2005 Dec 15;438:1017–21.Google Scholar
6Tsuda, M, Inoue, K, Salter, MW.Neuropathic pain and spinal microglia: a big problem from molecules in “small” glia. Trends Neurosci. 2005 Feb;28:101–7.Google Scholar
7Beggs, S, Salter, MW.Microglia-neuronal signalling in neuropathic pain hypersensitivity 2.0. Curr Opin Neurobiol. 2010 Aug;20:474–80.CrossRefGoogle ScholarPubMed
8Zhuo, M.Canadian Association of Neuroscience review: cellular and synaptic insights into physiological and pathological pain. EJLB-CIHR Michael Smith Chair in Neurosciences and Mental Health lecture. Can J Neurol Sci. 2005 Feb;32:27–36.CrossRefGoogle Scholar
9Hudson, AJ.Pain perception and response: central nervous system mechanisms. Can J Neurol Sci. 2000 Feb;27:2–16.CrossRefGoogle ScholarPubMed
10Treede, RD, Jensen, TS, Campbell, JN, et al.Neuropathic pain: redefinition and a grading system for clinical and research purposes. Neurology. 2008 Apr 29;70:1630–5.CrossRefGoogle Scholar
11Sommers, CJ, Zochodne, DW.Case studies in neurological pain. Cambridge Press, 2012 [in press].Google Scholar
12Bril, V, England, J, Franklin, GM, et al.Evidence-based guideline: treatment of painful diabetic neuropathy: report of the American Academy of Neurology, the American Association of Neuromuscular and Electrodiagnostic Medicine, and the American Academy of Physical Medicine and Rehabilitation. Neurology. 2011 May 17;76:1758–65.Google Scholar
13Dworkin, RH, O’Connor, AB, Audette, J, et al.Recommendations for the pharmacological management of neuropathic pain: an overview and literature update. Mayo Clin Proc. 2010 Mar;85:S3–14.CrossRefGoogle ScholarPubMed
14Attal, N, Cruccu, G, Haanpaa, M, et al.EFNS guidelines on pharmacological treatment of neuropathic pain. Eur J Neurol. 2006 Nov;13:1153–69.Google Scholar
15Toth, C, Lander, J, Wiebe, S.The prevalence and impact of chronic pain with neuropathic pain symptoms in the general population. Pain Med. 2009 Jul;10:918–29.CrossRefGoogle ScholarPubMed