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Non Ruptured MCA Aneurysms Presenting with Insular Related Symptoms

Published online by Cambridge University Press:  02 December 2014

Ramez Malak
Affiliation:
Division of Neurosurgery, Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada
Dank Khoa Nguyen
Affiliation:
Division of Neurology, Notre- Dame Hospital, Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada
Michel W. Bojanowski*
Affiliation:
Division of Neurosurgery, Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada
*
Department of Neurosurgery, Notre-Dame Hospital, Centre Hospitalier de l'Universitée Montré, 1560 Sherbrooke Street East, Montreal, Quebec, H2L 4M1, Canada.
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Abstract

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Objective:

To present a new semiological description of unruptured middle cerebral artery (MCA) aneurysms.

Methods:

We present a series of three MCA aneurysms presenting with progressive or paroxystic somatosensory symptoms in combination with visceral, motor, language or autonomic symptoms.

Results:

A surgical approach was proposed for two aneurysms, and both patients experienced complete resolution of their symptoms. The third aneurysm was successfully excluded by endovascular coiling but the symptoms persisted.

Conclusions:

To our knowledge this is the first description of unruptured aneurysms presenting with insular-related symptoms.

Type
Research Article
Copyright
Copyright © The Canadian Journal of Neurological 2010

References

1. Türe, U, Yasargil, DCH, Al-Mefty, O, Yasargil, MG. Topographic anatomy of the insular region. J Neurosurg. 1999;90:72033.CrossRefGoogle ScholarPubMed
2. Augustine, J. Circuitry and functional aspects of the insular lobe in primates including humans. Brain Res Rev. 1996;22:22944.CrossRefGoogle ScholarPubMed
3. Aziz, Q, Anderson, JLR, Valind, S, Sundin, A, Hamdy, S, Jones, AKP, et al. Identification of human brain loci processing oesophageal sensation using PET. Gastrenterology. 1997;113(1):509.CrossRefGoogle Scholar
4. Buchel, C, Morris, J, Dolan, RJ, Friston, KJ. Brain systems mediating aversive conditioning: an event related fMRI study Neuron. 1998;20(5):94757.CrossRefGoogle ScholarPubMed
5. Bucher, SF, Dieterich, M, Seelos, KC, Brandt, T. Sensorimotor cerebral activation during optokinetic nystagmus: a functional MRI study. Neurology. 1997;49:13707.CrossRefGoogle ScholarPubMed
6. Burton, H, Videen, TO, Raichle, ME. Tactile-vibration-activated foci in insular and parietal-opercular cortex studied with PET: mapping the second somatosensory area in humans. Somatosens Mot Res. 1993;10(3):297308.CrossRefGoogle Scholar
7. Cheung, RT, Hachinski, V. The insula and cerebrogenic sudden death. Arch Neur. 2000;57(12):16858.CrossRefGoogle ScholarPubMed
8. Chollet, F, Dipiero, V, Wise, RJS, Brooks, DJ, Dolan, RJ, Frackowiak, RSJ. The functional anatomy of motor recovery after stroke in humans: a study with PET. Ann Neurol. 1991;29:6371.CrossRefGoogle Scholar
9. Colebatch, JG, Deiber, MP, Passingham, RE, Friston, KJ, Frackowiak, RS. Regional cerebral blood flow during voluntary arm and hand movements in human subjects. J Neurophysiology. 1991;65:1392401.CrossRefGoogle ScholarPubMed
10. Dupont, S, Bouilleret, V, Hasboun, D, Semah, F, Baulac, M. Functional anatomy of the insula: new insights from imaging. Surg Radiol Anat. 2003;25:S1139.CrossRefGoogle ScholarPubMed
11. Ghaem, O, Mellet, E, Crivello, F, Tzourio, N, Mazoyer, B, Berthoz, A, et al. Mental navigation along memorized routes activates the hippocampus precuneus and insula. Neuroreport. 1997;8(3): 73944.CrossRefGoogle ScholarPubMed
12. Mesulam, MM, Mufson, EJ. The insula of Reil in man and monkey. Architectonics, connectivity, and function. In: Peters, A, Jones, EG, editors. Cerebral Cortex. Vol 4: Association and Auditory Cortices. New York: Plenum Press; 1985. p. 179226 CrossRefGoogle Scholar
13. Rumsey, JM, Horwitz, B, Donohue, BC, Nace, K, Maisog, JM, Andreason, P. Phonological and orthographic components of word recognition: a PET-rCBF study. Brain. 1997;120(5): 73959.CrossRefGoogle ScholarPubMed
14. Seeck, M, Zaim, S, Chaves-Vischer, V, Blanke, O, Maeder-Ingvar, M, Weissert, M, et al. Ictal bradycardia in a young child with focal cortical dysplasia in the right insular cortex. Eur J Ped Neur. 2003;7(4):17781.CrossRefGoogle Scholar
15. Xu, X, Fukuyama, H, Yazawa, S, Mima, T, Hanakawa, T, Magata, Y, et al. Functional localization of pain perception in the human brain studied by PET. Neuroreport. 1997;8(2):5559.CrossRefGoogle ScholarPubMed
16. Bertalanffy, H, Gilsbach, JM, Eggert, HR, Seeger, W. Microsurgery of deep-seated cavernous angiomas: report of 26 cases. Acta Neurochir. 1991;108:919.CrossRefGoogle ScholarPubMed
17. Duffau, H, Capelle, L, Lopes, M, Bitar, A, Sichez, JP, Van Effenterre, R. Medically intractable epilepsy from insular low-grade gliomas: improvement after an extended lesionectomy. Acta Neurochir. 2002;144(6):56372.CrossRefGoogle ScholarPubMed
18. Heffez, DS. Stereotactic transsylvian, transinsular approach for deep-seated lesions. Surg Neurol. 1997;48:11324.CrossRefGoogle ScholarPubMed
19. Lang, FF, Olansen, NE, DeMonte, F, Gokaslan, ZL, Holland, EC, Kalhorn, C, et al. Surgical resection of intrinsic insular tumors: complication avoidance. J Neurosurg. 2001;95(4):63850.CrossRefGoogle ScholarPubMed
20. Meyer, FB, Bates, LM, Goerss, SJ, Friedman, JA, Windschitl, WL, Duffy, JR, et al. Awake craniotomy for aggressive resection of primary gliomas located in eloquent brain. Mayo Clinic Proc. 76 (7):67787.CrossRefGoogle Scholar
21. Tirakotai, W, Sure, U, Benes, L, Krischek, B, Bien, S, Bertalanffy, H. Image-guided transsylvian, transinsular approach for insular cavernous angiomas. Neurosurg. 2003; 53(6):1299304.CrossRefGoogle ScholarPubMed
22. Vanaclocha, V, Saiz-Sapena, N, Garcia-Casasola, C. Surgical treatment of insular gliomas. Acta Neurochir. 1997;139(12): 112634.CrossRefGoogle ScholarPubMed
23. Yasargil, MG, von Ammon, K, Cavazos, E, Doczi, T, Reeves, JD, Roth, P. Tumors of the limbic and paralimbic systems. Acta Neurochir. 1992;118:4052.CrossRefGoogle ScholarPubMed
24. Zentner, J, Meyer, B, Stangl, A, Schramm, J. Intrinsic tumors of the insula: a prospective surgical study of 30 patients. J Neurosurg. 1996;85 (2):26371.CrossRefGoogle ScholarPubMed
25. Zimmerman, G, Lewis, AI, Tew, JM. Pure sylvian fissure arteriovenous malformations. JNS. 2000;92(1):3944.CrossRefGoogle ScholarPubMed
26. Nguyen, DK, Nguyen, DB, Malak, R, Leroux, JM, Carmant, L, Saint- Hilaire, JM, et al. Revisiting the role of the insula in refractory partial epilepsy. Epilepsia. 2009;50(3):51020.CrossRefGoogle ScholarPubMed
27. Penfield, W, Faulk, MJ. The insula: further observations on its functions. Brain. 1955;78:44570.CrossRefGoogle Scholar
28. Penfield, W, Jasper, H. Epilepsy and the functional anatomy of the human brain. Boston: Little Brown; 1954.CrossRefGoogle Scholar
29. Isnard, J, Guenot, M, Sindou, M, Mauguiere, F. Clinical manifestations of insular lobe seizures: a stereoelectroencephalographic study. Epilepsia 2004;45(9):107990.CrossRefGoogle Scholar
30. Ostrowsky, K, Isnard, J, Ryvlin, P, Guénot, M, Fischer, C, Mauguière, F. Functional mapping of the insular cortex: clinical implication in temporal lobe epilepsy. Epilepsia. 2000;41:6816.CrossRefGoogle ScholarPubMed
31. Malak, R, Bouthillier, A, Carmant, L, Cossette, P, Giard, N, Saint-Hilaire, JM, et al. Microsurgery of epileptic foci in the insular region. JNS. 2009;110:115363.CrossRefGoogle ScholarPubMed
32. Greenspan, JD, Winfield, JA. Reversible pain and tactile deficits associated with a cerebral tumor compressing the posterior insula and parietal operculum. Pain. 1992;50(1):2939.CrossRefGoogle ScholarPubMed