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Optic Neuritis and Myelopathy in Systemic Lupus Erythematosus

Published online by Cambridge University Press:  18 September 2015

Stephen Oppenheimer  and
B.I. Hoffbrand
Stephen Oppenheimer*
Affiliation:
Department of Medicine, Memorial University of Newfoundland, St. John's, Newfoundland
B.I. Hoffbrand
Affiliation:
Department of Medicine, The Whittington Hospital, London, England
*
Department of Clinical Neurological Sciences, University Hospital, 339 Windermere Road, P.O. Box 5339, London, Ontario, Canada N6A 5A5
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Abstract:

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The optic neuritis of systemic lupus erythematosus (S.L.E.) more frequently results in the persistence of a central scotoma or complete blindness after a single attack than demyelinating optic neuritis, although the initial clinical presentations may be identical. A significant number of patients, however, recover normal vision. Optic neuritis may be the presenting symptom of S.L.E. and as myelopathy may also occur in the course of the disease, confusion with multiple sclerosis may result, especially if there are no arthritic, cutaneous nor visceral manifestations. We report a case of lupus optic neuritis associated with anticardiolipin antibodies and a circulating lupus anticoagulant and suggest these may be a marker for vasculitic optic neuritis and play a role in its aetiology.

Type
Original Articles
Information
Canadian Journal of Neurological Sciences , Volume 13 , Issue 2 , May 1986 , pp. 129 - 132
Copyright
Copyright © Canadian Neurological Sciences Federation 1986

References

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