P.129 Bi-insular Responsive Neurostimulation Artifact on Scalp Electroencephalogram

Abstract

Background: Background: Responsive Neurostimulation (RNS) has proven efficacy in treating medically resistant epilepsy as an intracranial system detecting, recording and treating seizures automatically. No information exists pertaining to artifact characteristics of RNS findings in scalp EEG. Methods: A 30 year-old female was diagnosed using intracranial electroencephalography(iEEG), with bi-insular epilepsy, of unknown cause. She presented large number of focal unaware non-motor seizures and seizures with progression to bilateral tonic-clonic. She was implanted with bi-insular RNS. Results: During scalp EEG recordings, a prominent artifact was seen corresponding to an automatized discharge suspectedly evoked by the RNS trying to minimize the frequent epileptiform activity in her case. Figure 1 and 2 depict these findings. Conclusions: Artifact seen by the RNS in scalp EEG has not been previously described in scientific literature. These findings must be identified to better characterize the role of the RNS in EEG and treatment of seizure activity visible on scalp recordings.