Hostname: page-component-745bb68f8f-l4dxg Total loading time: 0 Render date: 2025-01-13T00:54:50.108Z Has data issue: false hasContentIssue false
  • English
  • Français

Paroxysmal Dyskinesia Associated with Hypoglycemia

Published online by Cambridge University Press:  18 September 2015

Brian J. Schmidt  and
Neelan Pillay
Brian J. Schmidt*
Affiliation:
Section of Neurology, Department of Internal Medicine, Faculty of Medicine, University of Manitoba, Winnipeg
Neelan Pillay
Affiliation:
Section of Neurology, Department of Internal Medicine, Faculty of Medicine, University of Manitoba, Winnipeg
*
Section of Neurology, Health Sciences Centre, 820 Sherbrook Street, Winnipeg Manitoba, Canada R3A 1R9
Rights & Permissions [Opens in a new window]

Abstract:

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The association of movement disorders with hypoglycemia has been rarely noted in the past. We recently observed 2 patients with documented hypoglycemia and paroxysmal dyskinesias. One patient had evidence of an insulin-secreting tumor. The other patient had insulin-dependent diabetes, and also experienced recurrent episodes of hypoglycemic hemiparesis. Classical adrenergic symptoms of hypoglycemia were absent in both patients. Our observations support the concept that the development of neuroglycopenic symptoms cannot be predicted from blood glucose measurements alone, but must depend on other factors controlling the availability or metabolism of glucose in the brain.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 20 , Issue 2 , May 1993 , pp. 151 - 153
Copyright
Copyright © Canadian Neurological Sciences Federation 1993

References

1.Golden, LA. Neurological manifestations in “hypoglycemic shock” (Sakel). Ann Intern Med 1937; II: 819–822.CrossRefGoogle Scholar
2.Newman, RP. Kinkel, WR. Paroxysmal choreoathetosis due to hypoglycemia. Arch Neurol 1984: 41: 341–342.CrossRefGoogle ScholarPubMed
3.Haan, J, Kremer, HPH, Padberg, G. Paroxysmal choreoathetosis as presenting symptom of diabetes mellitus. J Neurol Neurosurg Psychiatry 1989; 52: 133.CrossRefGoogle ScholarPubMed
4.Parajua, JL, Gallo, J, Goni, M, Locutura, J. Coreoatetosis paroxislica en el curso de coma hipoglucemico. Med Clin (Barcelona) 1986; 87: 521.Google Scholar
5.Sudhakar, S, Uitti, RJ, Ashenhurst, EM, Munoz-Garcia, D, Desai, HB. Paroxysmal dystonia from hypoglycemia. Can J Neurol Sei. 1987; 14: 215.Google Scholar
6.Padberg, GW, Bruyn, GW. Chorea - differential diagnosis. In: Vinken, PJ, Bruyn, GW, Klawans, HL, eds. Handbook of Clinical Neurology. Amsterdam: Elsevier 1986: 5(49): 549–564.Google Scholar
7.Buruma, OJS, Roos, RAC. Paroxysmal choreoathetosis. In: Vinken, PJ, Bruyn, GW, Klawans, HL, eds. Handbook of Clinical Neurology. Amsterdam: Elsevier, 1986: 5(49): 349–358.Google Scholar
8.Adams, RD, Victor, M. Principles of Neurology 4th ed. McGraw-Hill 1989; 852–853.Google Scholar
9.Malouf, R, Brust, JCM. Hypoglycemia: causes, neurological mani-festations, and outcome. Ann Neurol 1985; 17: 421–430.CrossRefGoogle Scholar
10.Morres, CA, Dire, DJ. Movement disorders as a manifestation of nonketotic hyperglycemia. J Emerg Med 1989; 7: 359–364.CrossRefGoogle ScholarPubMed
11.Bedwell, SF. Some observations on hemiballismus. Neurology 1960; 10: 619–622.CrossRefGoogle ScholarPubMed
12.Rector, WG, Herlong, HF, Moses, H. Nonketotic hyperglycemia appearing as choreoathetosis or ballismus. Arch Intern Med 1982; 142: 154–155.CrossRefGoogle ScholarPubMed
13.Tortoritis, M, Cornish, D, Thompson, F. Nonketotic hyperglycemia. Arch Intern Med 1982; 142: 1405.CrossRefGoogle Scholar
14.Vincent, FM. Hyperglycemia-induced hemichoreoathetosis: the presenting manifestation of a vascular malformation of the lenticular nucleus. Neurosurgery 1986; 18: 787–790.CrossRefGoogle ScholarPubMed
15.Foster, JW, Hart, RG. Hypoglycemic hemiplegia: two cases and a clinical review. Stroke 1987; 18: 944–946.CrossRefGoogle Scholar
16.Daggett, P, Nabarro, J. Neurological aspects of insulinomas. Postgrad Med J 1984; 60: 577–581.CrossRefGoogle ScholarPubMed
17.Boyle, PJ, Schwartz, NS, Shah, SD, Clutter, WE, Cryer, P. Plasma glucose concentrations at the onset of hypoglycemic symptoms in patients with poorly-controlled diabetes and in nondiabetics. N Engl J Med 1988; 318: 1487–1492.CrossRefGoogle ScholarPubMed
18.Portnoy, HD. Transient “ischemic” attacks produced by carotid stenosis and hypoglycemia. Neurology 1965; 15: 830–832.CrossRefGoogle ScholarPubMed
19.Wallis, WE, Donaldson, I, Scott, RS, Wilson, J. Hypoglycemia mas-querading as cerebrovascular disease (hypoglycemic hemiplegia). Ann Neurol 1985; 18: 510–512.CrossRefGoogle ScholarPubMed
20.Auer, RN, Siesjo, BK. Biological differences between ischemia. hypoglycemia, and epilepsy. Ann Neurol 1988; 24: 699–707.CrossRefGoogle ScholarPubMed