Hostname: page-component-cd9895bd7-jn8rn Total loading time: 0 Render date: 2024-12-27T08:34:28.488Z Has data issue: false hasContentIssue false

Problems in the Diagnosis and Treatment of Pseudotumor Cerebri

Published online by Cambridge University Press:  18 September 2015

Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

It is an honor to be asked to deliver the Silversides Lecture. Dr. Silversides’ clear understanding of the need for the collaboration of the basic and clinical sciences is a measure of the good sense for which he is admired. For a clinician, the greatest challenge to his clinical judgment lies in formulation of strategies to deal with vexing and serious conditions. Often we are called upon to treat conditions for which no satisfactory pathophysiologic mechanism has been elucidated. It is said that the clinician must frequently “get on top of the problem before he gets to the bottom of it.” In the spirit of all clinicians who seek better clinical approaches to poorly understood disease, I will devote this discussion to the diagnosis and treatment of pseudotumor cerebri.

Type
Special Features
Copyright
Copyright © Canadian Neurological Sciences Federation 1983

References

Ahlskog, J.E. and O’Neill, B.P., (1982) Pseudotumor cerebri. Ann. Int. Med. 97: 249256.CrossRefGoogle ScholarPubMed
Batnitzky, S., et. al., (1977) Iatrogenic intraspinal epidermoid tumors. J. Am. Med. Asso. 237: 148150.CrossRefGoogle ScholarPubMed
Beatty, R.A., (1982) Cervical-peritoneal shunt in the treatment of pseudotumor cerebri. J. Neurosurg. 57: 853855.CrossRefGoogle ScholarPubMed
Bird, A.C. and Sanders, M.D., (1973) Choroidal folds in association with papilledema. Br. J. Ophthalmol. 57: 8997.CrossRefGoogle Scholar
Bortoluzzi, M., Di Lauro, L. and Marini, G., (1982) Benign intracranial hypertension with spinal and radicular pain. J. Neurosurg. 57: 833836.CrossRefGoogle ScholarPubMed
Buchanan, T. A.S.andHoyt, W.F., (1981) Temporal visual field defects associated with nasal hypoplasia of the disc. Br. J. Ophthalmol. 65: 636640.CrossRefGoogle ScholarPubMed
Buchheit, W.A., et al., (1969) Papilledema and idiopathic intracranial hypertension: Report of familial occurrence. NewEng. J. Med. 280: 938942.Google Scholar
Chutorian, A.M., et. al., (1977) Benign intracranial hypertension and Bell’s palsy. New Eng. J. Med. 296: 12141215.CrossRefGoogle ScholarPubMed
Cooper, P.R., Moody, S., and Sklar, F., (1979) Chronic monitoring of intracranial pressure using an in vivo calibrating sensor: Experience in patients with pseudotumor cerebri. Neurosurg. 5: 666670.Google Scholar
Corbett, J.J., et. al., (1982) Visual loss in pseudotumor cerebri. Arch Neurol. 39: 461: 474.CrossRefGoogle ScholarPubMed
Corbett, J.J. and Mehta, M.P., (1983) Cerebrospinal fluid pressure in normal obese subjects and patients with pseudotumor cerebri. Neurology.CrossRefGoogle Scholar
Couch, J.R. and Weiss, S.A., (1974) Gliomatosis cerebri. Neurology 24: 504511.Google ScholarPubMed
Dersh, J. and Schlezinger, N.S., (1959) Inferior nasal quadrantanopsia in pseudotumor cerebri. Arch. Neurol. I: 695699.CrossRefGoogle ScholarPubMed
DeWecker, L., (1872) On incision of the optic nerve in cases of neuroretinitis. Int. Ophthalmol. Congr. Rep. 4: 1112.Google Scholar
Donat, J. F.,(1980) Acetazolamide-induced improvement in hydrocephalus. Arch. Neurol. 37: 376.Google ScholarPubMed
Eggers, H.M. and Sanders, M.D., (1980) Acquired optociliary shunt vessels in papilledema. Br. J. Ophthalmol. 64: 267271.CrossRefGoogle Scholar
Frisen, L., (1982) Swelling of the optic nerve head: A staging scheme. J. Neurol. Neurosurg. Psychiatr. 45: 1318.CrossRefGoogle ScholarPubMed
Frisen, L. and Holm, M., (1977) Visual field defects associated with choroidal folds. In: Neuro-opthalmology. C.V. Mosky Co., St. Louis (Glaser, J.S., ed) Vol. XI, Chapter 19.Google Scholar
Galbraith, J.E.K. and Sullivan, J.H., (1973) Decompression of the perioptic meninges for relief of papilledema. Am. J. Ophthalmol. 75: 687692.Google Scholar
Galvin, R. and Sanders, M.D., (1980) Peripheral retinal haemorrhages with papilledema. Br. J. Ophthalmol. 64: 262266.CrossRefGoogle Scholar
Gilland, O., Tourtellotte, W.W., O’Tauma, L. and Henderson, W.G., (1974) Normal spinal fluid pressure. J. Neurosurg. 40: 587593.CrossRefGoogle Scholar
Gowers, W.R., (1882) A Manual and Atlas of Medical Ophthalmology. 2nd Edition, Philadelphia, Blakiston.Google Scholar
Green, G.J., et al., (1980) Ischemic optic neuropathy in chronic papilledema. Arch. Opthalmol. 98: 502504.CrossRefGoogle ScholarPubMed
Griberg, T.R. and Grove, A.S., (1980) Subretinal neovascularization and choroidal folds. Ann. Ophthalmol. 3: 245250.Google Scholar
Gucer, G. and Viernstein, L., (1978) Long-term intracranial pressure recording in the management of pseudotumor cerebri. J. Neurosurg. 49: 256263.CrossRefGoogle ScholarPubMed
Guisado, R., et. al., (1975) Rebound phenomenon complicating cerebral dehydration with glycerol. J. Neurosurg. 42: 226228.CrossRefGoogle ScholarPubMed
Halpern, J.I. and Gordon, W.H. Jr., (1981) Trochlear nerve palsy as a false localizing sign. Ann. Ophthalmol. 9: 5356.Google Scholar
Hart, R.G. and Carter, J.E., (1982) Pseudotumor cerebri and facial pain. Arch. Nerol. 39: 440441.CrossRefGoogle ScholarPubMed
Hayreh, S.S., (1968) Pathogenesis of oedema of th optic disc. Doc. Opthalmol. 24: 289411.CrossRefGoogle Scholar
Hitchings, R.W., et. al., (1976) Hemorrhages with optic nerve drusen. Archo. Neurol. 33: 675677.CrossRefGoogle ScholarPubMed
Huber, A., (1971) Eye Symptoms in Brain Tumors. C.V. Mosby Co., St Louis, p. 104.Google Scholar
Jamison, R.R., (1978) Subretinal neovascularization and papilledema associated with pseudotumor cerebri. Am. J. Opthalmol. 85: 7881.Google ScholarPubMed
Jefferson, A. and Clark, J., (1976) Treatment of benign intracranial hypertension by dehydrating agents with particular reference to the measurement of the blind spot area as a means of recording improvement. J. Neurol. Neurosurg. Psychiatr. 39: 627639.CrossRefGoogle Scholar
Johnston, I.H. and Paterson, A., (1972) Benign intracranial hypertension: Aspects of diagnosis and treatment. In: The Optic Nerve. Cant, J.S., (ed), London: Henry Kingston, pp. 155165.Google Scholar
Johnston, I. and Paterson, A., (1974) Benign intracranial hypertension II. CSF pressure and circulation. Brain. 97: 301312.Google ScholarPubMed
Kaye, A.H., Galbraith, J.E.K. and King, J., (1981) Intracranial pressure following optic nerve decompression for benign intracranial hypertension. Case Report. J. Neurosurg. 55: 453457.Google ScholarPubMed
Keane, J.R. (1981) Papilledema with unusual hemorrhages. Arch Opthalmol. 99: 262263.Google ScholarPubMed
Keltner, J.L., et. al., (1977) Optic nerve decompression. A clinical pathologic study. Arch. Opthalmol. 95: 97104.CrossRefGoogle ScholarPubMed
Kirkham, T.H., et. al., (1973) Unilateral papilledema in benign intracranial hypertension. Canad. J. Opthalmol. 8: 533538.Google ScholarPubMed
Lorentzen, S.E., (1966) Drusen of the Optic Disc: A clinical & genetic study. Acta Ophthalmol. Supp. 90.Google ScholarPubMed
Manno, N.J. et al., (1962) Intraspinal epidermoids. J. Neurosurg. 19: 754756.CrossRefGoogle ScholarPubMed
McCammon, A., et al., (1981) Transient oculomotor paresis in pseudotumor cerebri. Neurology. 31: 182184.Google Scholar
McCarthy, K.D. and Reed, D.J., (1974) The effect of acetazolamide and furosemide on CSF production and choroid plexus carbonic anhydrase activity. J. Pharmacol. Exp. Therapy 189: 194201.Google Scholar
Merikangas, J.R., (1978) Skew deviation in pseudotumor cerebri. Ann. Neurol. 4: 583.CrossRefGoogle ScholarPubMed
Morse, P.H., et. al., (1981) Bilateral juxtapapillary subretinal neovascularization associated with pseudotumor cerebri. Am. J. Ophthalmol. 91: 312317.CrossRefGoogle ScholarPubMed
Morris, A.T. and Sanders, M.D., (1980) Macular changes resulting from papilleodema. Br. J. Ophthalmol. 64: 211216.Google Scholar
Neblett, C.R., et al., (1972) Effect of cardiac glycosides on human CSF production. Lancet 2: 10081009.CrossRefGoogle Scholar
Newborg, B., (1974) Pseudotumor cerebri treated by rice reduction diet. Arch. Int. Med. 133: 802808.CrossRefGoogle ScholarPubMed
Oakley, D. E. and Ellis, P. P., (1976) Glycerol and hyperosmolar nonketotic coma. Am. J. Ophthalmol. 81: 469472.CrossRefGoogle ScholarPubMed
Perlmutter, J.C., et al., (1980) Disappearing opticociliary shunt vessels and pseudotumor cerebri. Am. J. Opthalmol. 89: 703707.Google ScholarPubMed
Perret, G.E. and Graf, C.J., (1977) Subgaleal shunt for temporary ventricular decompression and subdural drainage. J. Neurosurg. 47: 590595.CrossRefGoogle Scholar
Quigley, H.A., Addicks, E.M. and Green, W.R. (1982) Optic nerve damage in human glaucoma 111. Quantitative correlation of nerve fiber layer loss and visual field defect in glaucoma, ischemic neuropathy, papilledema and toxic neuropathy. Arch. Opthalmol. 100: 135146.CrossRefGoogle Scholar
Reid, A.C. and Thomson, J. A., (1981) Absence of significant endocrine deficiencies in benign intracranial hypertension. J. Neurol. Neurosurg. Pshychiatr. 44: 731734.CrossRefGoogle ScholarPubMed
Ridsdale, L. and Moseley, I., (1978) Thoracolumbar intraspinal tumors presenting features of raised intracranial pressure. J. Neurol. Neurosurg. Pshychiatr. 41: 737742.CrossRefGoogle ScholarPubMed
Rottenberg, D. A., et. al., (1977) The effect of oral glycerol on intraventricular pressure in man. Neurology 27: 600608.Google ScholarPubMed
Rush, J.A., (1980) Pseudotumor cerebri. Clinical profile and visual outcome in 63 patients. Mayo Clin. Proc. 55: 541546.Google ScholarPubMed
Savino, P. and Glaser, J., (1977) Pseudopapilledema versus papilledema. International Opthalmology Clinics. In: Clinical Neurooph-thalmology: The Afferent Visual System. Vol. 17, No. I.Google Scholar
Shapiro, J.M., (1979) Optic topography in experimental glaucoma. Invest. Ophthalmol. 18: suppl. 166.Google Scholar
Snyder, D.A. and Frenkel, M., (1972) An unusual presentation of pseudotumor cerebri. Ann. Ophthalmol. 11: 18231827.Google Scholar
Spallone, A., (1981) Benign intracranial hypertension versus intracranial arteriovenous malformation. A possible CT dilemma. Acta Neurochir. (Wein) 58: 7584.CrossRefGoogle Scholar
Spence, J.D., et al., (1980) Benign intracranial hypertension without papilledema: Role of 24 hour CSF pressure monitoring in diagnosis and management. Neurosurg. 7: 326332.Google ScholarPubMed
Troost, B.T., et. al., (1979) Sudden monocular visual loss in pseudotumor cerebri. Arch. Neurol. 36: 440442.CrossRefGoogle ScholarPubMed
Vander Ark, G.D., et. al., (1971) Pseudotumor cerebri treated with lumbar-peritoneal shunt. J. Am. Med. Asso. 217: 18321834.Google ScholarPubMed
Vassilouthis, J., (1979) Cerebral arteriovenous malformation with intracranial hypertension. Surg. Neurol. 41: 402404.Google Scholar
Weisberg, L.A.,(1975) Benign intracranial hypertension. Medicine 54: 197207.CrossRefGoogle ScholarPubMed
Wilson, D.H. and Gardner, W.J., (1966) Benign intracranial hypertension with particular reference to its occurrence in fat young women. Canad. Med. Assn. H. 95: 102105.Google ScholarPubMed