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Pseudotumor Cerebri

Published online by Cambridge University Press:  18 September 2015

F.L. Moffat
F.L. Moffat*
Affiliation:
Division of Neurosurgery, Faculty of Medicine, University of Toronto and the Toronto General Hospital
*
Division of Neurosurgery, Toronto General Hospital, Toronto, M5G 1L7, Canada.
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Summary:

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Pseudotumor cerebri is a clinical syndrome in which signs and, sometimes, symptoms of raised intracranial pressure are present hut in which mental and neurological function are unaffected. Therefore, the diagnosis is reached after mass and other structural causes of raised pressure have been excluded.

Many causes of pseudotumour have been suggested, not all of them well documented. Pathogenesis, however, includes cerebral edema, increased cerebral blood volume, and decreased cerebro spinal fluid (CSF) absorption.

Except for the risk of vision in a minority of cases, the prognosis is excellent.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 5 , Issue 4 , November 1978 , pp. 431 - 436
Copyright
Copyright © Canadian Neurological Sciences Federation 1978

References

REFERENCES

Bass, M.H., Fisch, G. R. (1961). Increased intracranial pressure with bulging fontanelle. A symptom of vitamin A deficiency in infants. Neurology. 11, 1091–1094CrossRefGoogle ScholarPubMed
Beller, A. J. (1964). Benign post-traumatic intracranial hypertension. Journal of Neurology. Neurosurgery and Psychiatry, 27. 149–152CrossRefGoogle ScholarPubMed
Benini, A. (1973). A modified technique for the construction of a lumbo-peritoneal shunt preliminary report and technical note. Acta Neurochirurgica, 28, 189–192CrossRefGoogle ScholarPubMed
Bercaw, B. L, Greer, M. (1970). Transport of intrathecal 1311 RISA in benign intracranial hypertension. Neurology (Minneap.). 20. 787–790CrossRefGoogle Scholar
Bettman, J.W., Daroff, R.B., Sanders, M. D.Hoyt, W. F. (1968). Papilledema and asymptomatic intracranial hypertension in systematic lupus erythematosus. Archives of Ophthalmology, 80, 189–193.CrossRefGoogle Scholar
Boddie, H.G., Banna, H., Bradley, W.G. (1974). “Benign” intracranial hypertension. A survey of the clinical and radiological features and long-term prognosis. Brain. 97, 313–326CrossRefGoogle ScholarPubMed
Boe, R., Conner, C.S. (1973). Letter: Pseudotumor cerebri. Journal of the American Medical Association. 226, 567.CrossRefGoogle ScholarPubMed
Bradshaw, P. (1956). Benign intracranial hypertension. Journal of Neurology. Neurosurgery and Psychiatry. 19. 28–41CrossRefGoogle ScholarPubMed
Bray, P.F., Herbst, J.J. (1973). Pseudotumor cerebri as a sign of “catch up” growth in cystic fibrosis. American Journal of Disease in Childhood. 126. 78–79Google ScholarPubMed
BRITISH MEDICAL JOURNAL. Editorial (1970). 3. 536–537Google Scholar
Buchheit, W.A., Burton, C.Haag, B., Shaw, D. (1969). Papilledema and idiopathic intracranial hypertension. New England Journal of Medicine. 280, 938–942CrossRefGoogle ScholarPubMed
Burde, R.M., Karp, J.S., Miller, R.N. (1974). Letter: Reversal of visual defect with optic nerve decompression in longstanding pseudotumor cerebri. American Journal of Ophthalmology, 77 (5). 770–772CrossRefGoogle ScholarPubMed
Capitanio, M.A., Kirkpatrick, J.A. (1969). Widening of the cranial sutures. Radiology, 92. 53–59CrossRefGoogle ScholarPubMed
Carlow, T.J., Glaser, J.S. (1974). Pseudotumor cerebri syndrome in systemic lupus erythematosis. Journal of the American Medical Association. 228. 197–200CrossRefGoogle Scholar
Chun, R.W.N., Smith, N.J., Forster, F.M. (1961). Papilledema in Sydenham’s chorea. American Diseases of Childhood. 101, 641–644Google ScholarPubMed
Cohen, D.N. (1973). Intracranial hypertension and papilledema associated with nalidixic acid therapy. American Journal of Ophthalmology. 76. 680–682CrossRefGoogle ScholarPubMed
Cornfield, D., Cooke, R.E. (1952). Vitamin A deficiency: case report. Unusual manifestations in a 5½ month old baby. Pediatrics. 10. 33–39Google Scholar
Delaney, P., Schellinger, D. (1976). Computerized tomography and benign intracranial hypertension. Journal of the American Medical Association. 238. 951–952CrossRefGoogle Scholar
Diliberti, J., O’brien, M.I., (1975). Pseudotumor following patent ductus arteriosus ligation. Journal of Pediatrics. 87(3). 489.CrossRefGoogle Scholar
Edmunds, C., Behrens, M., Lewis, I., Lennon, R. (1973). Letter: Pseudotumor cerebri and low vitamin A intake. Journal of the American Medical Association, 226, 674.CrossRefGoogle ScholarPubMed
Feldman, M.H., Schlezinger, N.S. (1970). Benign intracranial hypertension associated with hypervitaminosis A. Archives of Neurology. 22. 1–7CrossRefGoogle ScholarPubMed
Foley, K.M., Posner, J.B. (1975). Does pseudotumor cerebri cause the empty sella syndrome? Neurology (Minneap.), 25. 565–569CrossRefGoogle ScholarPubMed
Foley, J. (1955). Benign forms of intracranial hypertension “toxic” and “otitic” hydrocephalus. Brain. 78. 1–41CrossRefGoogle ScholarPubMed
Galbraith, J.E.K., Sullivan, J.H. (1973). Decompression of the perioptic meninges for relief of papilledema. American Journal of Ophthalmology. 76. 687–692CrossRefGoogle ScholarPubMed
Gerber, A.M., Mullan, S. (1974). Intracranial hypertension. Postgraduate Medicine. 55. 83–88CrossRefGoogle ScholarPubMed
Giles, C.L., Soble, A.R. (1971). Intracranial hypertension and tetracycline therapy. American Journal of Ophthalmology, 72, 981–892CrossRefGoogle ScholarPubMed
Grant, D.N. (1971). Benign intracranial hypertension. A review of 79 cases in infancy and childhood. Archives of Disease in Childhood. 46. 651–655CrossRefGoogle ScholarPubMed
Greer, M. (1968). Management of benign intracranial hypertension (pseudotumor cerebri). In: Clinical Neurosurgery. Williams & Wilkins Co.. Baltimore. 15, 161–174Google Scholar
Greer, M. (1962). Benign intracranial hypertension 1. Mastoiditis and lateral sinus obstruction. Neurology. 12. 472–476CrossRefGoogle Scholar
Greer, M. (1963). Benign intracranial hypertension III. Pregnancy. Neurology. 13. 670–672CrossRefGoogle ScholarPubMed
Greer, M. (1964). Benign intracranial hypertension IV. Menarche. Neurology. 14. 569–573CrossRefGoogle Scholar
Greer, M. (1964). Benign intracranial hypertension V. Menstrual dysfunction. Neurology, 14. 668–673CrossRefGoogle ScholarPubMed
Greer, M. (1965). Benign intracranial hypertension VI. Obesity. Neurology. 15, 382–388CrossRefGoogle ScholarPubMed
Greer, M. (1967). Benign intracranial hypertension (pseudotumor cerebri). In: Pediatric Clinics of North American. 14. 819–830CrossRefGoogle Scholar
Guidetti, B., Giuffrie, R., Gamba CORTA, D. (1968). Follow-up studies of 100 cases of pseudotumor cerebri. Acta Neurochirurgica, 18, 259–267CrossRefGoogle ScholarPubMed
Hawkins, T.E., Burlon, D.F. (1974). Vitamin A intoxication. Journal of the American Osteopathic Association, 73. 371–375Google ScholarPubMed
Hayes, K.C., McCombs, H.L., Faherty, T.P. (1971). The fine structure of vitamin A deficiency II. Arachnoid granulations and CSF pressure. Brain, 94. 213–224CrossRefGoogle ScholarPubMed
Hochman, H.I., Mejlszenkier, J.D. (1977). Cataracts and pseudotumor cerebri in an infant with vitamin D-deficient rickets. Journal of Pediatrics. 90, 252–254CrossRefGoogle Scholar
Howe, J.G., Saunders, M., Clarke, P.R.R. (1973). Familial benign intracranial hypertension. Acta Neurochirurgica, 29, 173–175CrossRefGoogle Scholar
Huckman, M.S., Fox, J.S., Ramsey, R.G., Penn, R.D. (1976). Computed tomography in the diagnosis of pseudotumor cerebri. Radiology, 119, 593–597CrossRefGoogle ScholarPubMed
Jackson, A.H., Griffith, J.F. (1975). Histiocytosis X with benign intracranial hypertension. Developmental Medicine and Child Neurology, 17, 783–787CrossRefGoogle ScholarPubMed
Janeway, R., Kelly, D.L. (1966). Papilledema and hydrocephalus associated with recurrent polyneuritis, Guiltlain-Barré type. Archives of Neurology, 15, 507–514CrossRefGoogle ScholarPubMed
Johnston, I. (1973). Reduced CSF absorption syndrome. Reappraisal of benign intracranial hypertension and related conditions. The Lancet, 2. 418–421CrossRefGoogle ScholarPubMed
Johnston, I. (1975). The definition of a reduced CSF absorption syndrome: a reappraisal of benign intracranial hypertension and related conditions. Medical Hypotheses. 1, 10–14CrossRefGoogle Scholar
Johnston, I., Paterson, A. (1974). Benign intracranial hypertension I. Diagnosis and prognosis. Brain. 97, 289–300CrossRefGoogle ScholarPubMed
Johnston, I., Paterson, A. (1974). Benign intracranial hypertension II. CSF pressure and circulation. Brain, 97, 301–312CrossRefGoogle ScholarPubMed
Kirkham, T.H., Sanders, M.D., Sapp, G.A. (1973). Unilateral papilledema in benign intracranial hypertension. Canadian Journal of Ophthalmology. 8, 533–538Google ScholarPubMed
Lipton, H.I., Michelson, P.E. (1972). Pseudotumor cerebri syndrome without papilledema. Journal of the American Medical Association. 220. 1591–1592CrossRefGoogle ScholarPubMed
Litman, N., Kanter, A.I., Finberg, L. (1975). Galactokinasc deficiency presenting as pseudotumor cerebri. Journal of Pediatrics. 86. 410–412CrossRefGoogle ScholarPubMed
Lombaert, A., Carton, H. (1976). Benign intracranial hypertension due to hypervita-minosis A in adults and adolescents. European Neurology, 14, 340–350CrossRefGoogle ScholarPubMed
Mathew, N.T., Meyer, J.S., Ott, E.O. (1975). Increased cerebral blood volume in benign intracranial hypertension. Neurology (Minneap.), 25(7). 646–649CrossRefGoogle ScholarPubMed
Mushet, G.R. (1977). Letter: Pseudotumor and nitrofurantoin therapy. Archives of Neurology, 34(4), 257CrossRefGoogle ScholarPubMed
Neville, B.G.R., Wilson, J. (1970). Benign intracranial hypertension following corticosteroid withdrawal in childhood. British Medical Journal, 3, 554–556CrossRefGoogle ScholarPubMed
Newborg, B. (1974). Pseudotumor cerebri treated by rice/reduction diet. Archives of Internal Medicine, 133, 802–807CrossRefGoogle ScholarPubMed
Oldstone, M.B.A. (1966). Disturbance of pituitary-adrenal interrelationships in benign intracranial hypertension. Journal of Clinical Endocrinology, 26, 1366–1369CrossRefGoogle ScholarPubMed
Olson, C.A., Riley, H.D. (1966). Complications of tetracycline therapy. Journal of Pediatrics, 68, 783–791CrossRefGoogle ScholarPubMed
Otuama, L.A., Kirkman, H.N., James, P.M. (1973). Raised intracranial pressure after hyperalimentation. The Lancet, 2, 1101CrossRefGoogle ScholarPubMed
Paterson, R., Depasquale, N., Mann, S. (1961). Pseudotumor cerebri. Medicine, 40, 85–99CrossRefGoogle ScholarPubMed
Powell, J.L. (1972). Pseudotumor cerebri and pregnancy. Obstetrics and Gynecology, 40(5), 713–718Google ScholarPubMed
Raichle, M.E., Gado, M.H., Eichling, J.O., Phelps, M.E., Grubb, R.L., Hoffman, E.J. (1974). Abstr.: Cerebral haemodynamics and metabolism in pseudotumor cerebri. Neurology (Minneap.) 24, 397.Google Scholar
Rao, K.G. (1974). Pseudotumor associated with nalidixic acid. Urology, 4, 204–207Google ScholarPubMed
Rothner, A.D., Brust, J.C.M. (1974). Pseudotumor cerebri. A report of a familial occurrence. Archives of Neurology, 30, 110–111CrossRefGoogle ScholarPubMed
Roussounis, S.H. (1976). Benign intracranial hypertension after withdrawal of topical steroids in an infant. British Medical Journal, 2(6035), 564.CrossRefGoogle ScholarPubMed
Sahs, A.L., Joynt, R.I. (1956). Brain swelling of unknown cause. Neurology (Minneap.). 6. 791–803CrossRefGoogle Scholar
Saxena, V.K., Heilpern, R.J., Murphy, S.F. (1976). Pseudotumor cerebri – a complication of parenteral hyperalimentation. Journal of the American Medical Association. 235(19), 2124.CrossRefGoogle ScholarPubMed
Sharma, D.B., James, A. (1974). Letter: Benign intracranial hypertension associated with nitrofurantoin therapy. British Medical Journal, 4(5947), 771.CrossRefGoogle ScholarPubMed
Sondheimer, F.K., Grossman, H., Winchester, P. (1970). Suture diastasis following rapid weight gain. Archives of Neurology. 23, 314–318CrossRefGoogle ScholarPubMed
Traviesa, D.C., Schwartzman, R.I., Glaser, J.S., Savino, P. (1976). Familial benign intracranial hypertension. Journal of Neurology. Neurosurgery and Psychiatry, 39, 420–423CrossRefGoogle ScholarPubMed
Vanderark, G.D., Kempe, L.G., Smith, D.R. (1971). Pseudotumor cerebri treated with lumboperitoneal shunt. Journal of the American Medical Association, 217. 1832–1834.CrossRefGoogle Scholar
Vollbracht, R., Gilroy, J. (1976). Vitamin A-induced benign intracranial hypertension. Canadian Journal of Neurological Sciences. 3(1). 59–61CrossRefGoogle ScholarPubMed
Weisberg, L.A., Housepian, E.M., Saur, D.P. (1975). Empty sella syndrome as a complication of benign intracranial hypertension. Journal of Neurosurgery, 43, 177–180CrossRefGoogle ScholarPubMed
Weisberg, L.A. (1975). The syndrome of increased intracranial pressure without localizing signs: a reappraisal. Neurology (Minneap.), 25(1), 85–88CrossRefGoogle ScholarPubMed
Weisberg, L.A. (1975). Benign intracranial hypertension. Medicine (Bait.), 54(3), 197–207CrossRefGoogle ScholarPubMed
Weisberg, L.A. (1977). Letter: Computerized tomography and benign intracranial hypertension. Journal of the American Medical Association. 239. 871.CrossRefGoogle Scholar
Wilson, D.H., Gardner, W.J. (1966). Benign intracranial hypertension with particular reference to its occurrence in fat young women. Canadian Medical Association Journal, 95, 102–105Google ScholarPubMed
Zial, M. (ED.), Abassioum, K. (1973). Intracranial hypertension.’papilledema and normal neurological investigations. Clinical Pediatrics. 12. 30A-31A.Google Scholar
Zuidema, G.D., Cohen, S.J. (1954). Pseudotumor cerebri. Journal of Neurosurgery, 11. 433–441CrossRefGoogle ScholarPubMed