Hostname: page-component-78c5997874-lj6df Total loading time: 0 Render date: 2024-11-13T01:30:03.711Z Has data issue: false hasContentIssue false

Stereotactic Radiosurgery for Acoustic Neuroma: A Canadian Perspective

Published online by Cambridge University Press:  18 September 2015

Ian B. Ross*
Affiliation:
Section of Neurosurgery, University of Manitoba, Winnipeg
Charles H. Tator
Affiliation:
Division of Neurosurgery, University of Toronto, Toronto
*
Section of Neurosurgery, University of Manitoba, Z3017-409 Tache Ave, Winnipeg, MB, Canada R2H 2A6
Rights & Permissions [Opens in a new window]

Abstract:

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Stereotactically delivered radiation is now an accepted treatment for patients with acoustic neuroma. In some cases, patient preference may be the reason for its selection, while in others neurosurgeons may select it for patients who are elderly or have significant risk factors for conventional surgery. The majority of patients with acoustic neuroma treatment with stereotactic radiosurgery have been treated with the Gamma Knife, with follow ups of over 25 years in some instances. Other radiosurgical modalities utilizing the linear accelerator have been developed and appear promising, but there is no long-term follow up. Canada does not possess a Gamma Knife facility, and its government-funded hospital and medical insurance agencies have made it difficult for patients to obtain reimbursement for Gamma Knife treatments in other countries. We review the literature to date on the various forms of radiation treatment for acoustic neuroma and discuss the current issues facing physicians and patients in Canada who wish to obtain their treatment of choice.

Résumé:

RÉSUMÉ:

L'irradiation stéréotaxique est maintenant un traitement reconnu chez les patients qui ont un neurinome acoustique. Dans certains cas, la préférence du patient peut être la raison de ce choix, alors dans d'autres cas le neurochirurgien peut choisir ce traitement pour les patients qui sont âgés ou chez qui la chirurgie conventionnelle présente des facteurs de risque importants. La majorité des patients qui sont traités par radiochirurgie stéréotaxique pour un neurinome acoustique ont été traités au moyen du scalpel gamma, avec un suivi de plus de 25 ans dans certains cas. D'autres modalités radiochirurgicales utilisant l'accélérateur linéaire ont été développées et semblent prometteuses, mais un suivi à long terme n'est pas disponible. Le Canada n'a pas d'institution qui possède de scalpel gamma et le fait que ses hôpitaux sont subventionnés par des fonds publiques et les limites établies par les compagnies d'assurance médicale font qu'il est difficile pour les patients d'obtenir un remboursement pour le traitement par le scalpel gamma dans d'autres pays. Nous revoyons la littérature sur les différentes formes d'irradiation pour le traitement du neurinome acoustique et nous discutons des problèmes auxquels font face au Canada les médecins et les patients qui désirent obtenir le traitement de leur choix.

Type
Original Articles
Copyright
Copyright © Canadian Neurological Sciences Federation 1998

References

REFERENCES

1. Leksell, L. The stereotactic method and radiosurgery of the brain. Acta Chir Scand 1951; 102: 316319.Google Scholar
2. Leksell, L. A note on the treatment of acoustic tumors. Acta Chir Scand 1971; 137: 763765.Google Scholar
3. Laperriere, NJ, Bernstein, M. Stereotactic radiosurgery. Can J Neurol Sci 1997; 24: 9394.Google Scholar
4. Verhey, LH, Smith, V, Serago, CF. Comparison of radiosurgery treatment modalities based on physical dose distributions. Int J Radiat Oncol Biol Phys 1998; 40: 497505.Google Scholar
5. Noren, G, Arndt, J, Hindmarsh, T. Stereotactic radiosurgery in cases of an acoustic neuroma: further experiences. Neurosurgery 1983; 13: 1222.Google Scholar
6. Noren, G, Greitz, D, Hirsch, A, Lax, I. Gamma knife surgery in acoustic tumors. Acta Neurochir Suppl Wien 1993; 58: 104107.Google Scholar
7. Noren, G. Gamma knife radiosurgery for acoustic neuromas. In: Gildenberg, PL, Tasker, RR, eds. Textbook of Stereotactic and Functional Neurosurgery. New York: McGraw Hill, 1998: 835844.Google Scholar
8. Pollock, BE, Lunsford, LD, Kondziolka, D, Flickinger, JC, Bissonette, DJ, et al. Outcome analysis of acoustic neuroma management: comparison of microsurgery and stereotactic radiosurgery. Neurosurgery 1995; 36: 215229.CrossRefGoogle ScholarPubMed
9. Kondziolka, D, Lunsford, LD, Flickinger, JC. Stereotactic radiosurgery for acoustic tumors: technique and results. Tech Neurosurg 1997; 3: 154161.Google Scholar
10. Foote, RL, Coffey, RJ, Swanson, JW, Harner, SG, Beatty, CW, et al. Stereotactic radiosurgery using the gamma knife for acoustic neuromas. Int J Radiat Oncol Biol Phys 1995; 32: 11521160.Google Scholar
11. Flickinger, JC, Kondziolka, D, Pollock, BE, Lunsford, LD. Evolution in technique for vestibular schwannoma radiosurgery and effect on outcome. Int J Radiat Oncol Biol Phys 1996; 36: 275280.Google Scholar
12. Mendenhall, WM, Friedman, WA, Buatti, JM, Bova, FJ. Preliminary results of linear accelerator radiosurgery for acoustic schwannomas. J Neurosurg 1996; 85: 10131019.Google Scholar
13. Mendenhall, WM, Friedman, WA, Bova, FJ. Linear accelerator-based stereotactic radiosurgery for acoustic schwannomas. Int J Radiat Oncol Biol Phys 1994; 28 803810.Google Scholar
14. Valentino, V, Raimondi, AJ. Tumor response and morphological changes of acoustic neuromas after radiosurgery. Acta Neurochir Wien 1995; 133: 157163.CrossRefGoogle ScholarPubMed
15. Andrews, DW, Silverman, CL, Glass, J, et al. Preservation of cranial nerve function after treatment of acoustic neuronomas with fractionated stereotactic radiotherapy, preliminary observations in 26 patients. Stereotact Funct Neurosurg 1995; 64: 165182.Google Scholar
16. Varlotto, JM, Schrieve, DC, Alexander, E 3rd, et al. Fractionated stereotactic radiotherapy for the treatment of acoustic neuromas: preliminary results. Int J Radiat Oncol Biol Phys 1996; 36: 141145.Google Scholar
17. Clark, BG, Souhami, L, Pla, C, et al. The integral biologically effective dose to predict brain stemtoxicity of hypofractionated stereotactic radiotherapy. Int J Radiat Oncol Biol Phys 1998; 40: 667675.Google Scholar
18. Schwartz, M. Stereotactic radiosurgery: comparing different technologies. Can Med Assoc J 1998; 158: 625628.Google Scholar
19. Young, C, Summerfield, R, Schwartz, M, O’Brien, P, Ramani, R. Radiosurgery for arteriovenous malformations: the University of Toronto Experience. Can J Neurol Sci 1997; 24: 99105.Google Scholar
20. Schwartz, ML, Young, C, O’Brien, P, Ramaini, R. Radiosurgery for acoustic neuromas: the Toronto experience. Can J Neurol Sci 1994; 21(Suppl 2): S15-S16.Google Scholar