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A Syndrome of Brain, Inner Ear and Retinal Microangiopathy

Published online by Cambridge University Press:  18 September 2015

D.J. MacFadyen ,
R.J. Schneider  and
I.A. Chisholm
D.J. MacFadyen*
Affiliation:
Departments of Clinical Neurological Sciences, University Hospital, Saskatoon
R.J. Schneider
Affiliation:
Departments of Ophthalmology, University Hospital, Saskatoon
I.A. Chisholm
Affiliation:
Departments of Ophthalmology, University Hospital, Saskatoon
*
Department of Clinical Neurological Science, University Hospital, Saskatoon, Saskatchewan, Canada S7N 0X0
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Abstract:

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We report the seventh case of a self-limiting syndrome of brain, inner ear and retinal microangiopathy which affects adult women producing mild to moderate mental status and personality changes, mild pyramidal and cerebellar dysfunction, patchy and asymmetrical visual loss secondary to non-inflammatory retinal infarctions, and asymmetrical neurosensory hearing loss. There is no clinical or laboratory evidence of involvement beyond the brain, the eyes and the ears. Magnetic resonance imaging or brain biopsy in previously reported cases best outline the brain pathology: multiple microinfarcts. All cases have been treated with steroids or cyclophosphamide. The etiology is unknown but may be related to systemic lupus erythematosus.

Type
Original Articles
Information
Canadian Journal of Neurological Sciences , Volume 14 , Issue 3 , August 1987 , pp. 315 - 318
Copyright
Copyright © Canadian Neurological Sciences Federation 1987

References

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