Hostname: page-component-cd9895bd7-dk4vv Total loading time: 0 Render date: 2024-12-28T01:53:56.378Z Has data issue: false hasContentIssue false
  • English
  • Français

Visual evoked potentials and brain stem auditory potentials in Friedreich's ataxia — A longitudinal study

Published online by Cambridge University Press:  18 September 2015

J. Bogacz ,
C. Chouza ,
S. Romero ,
A. Bogacz ,
H. Correa  and
A. Barbeau
J. Bogacz
Affiliation:
Laboratorio de Electroencefalographia y Neurofisiologia Clinica
C. Chouza
Affiliation:
The Departamento de Investigacion Clinic
S. Romero
Affiliation:
The Departamento de Investigacion Clinic
A. Bogacz
Affiliation:
Laboratorio de Electroencefalographia y Neurofisiologia Clinica
H. Correa
Affiliation:
The Departamento de Investigacion Clinic
A. Barbeau*
Affiliation:
Instituto de Neurologia, Hospital de Clinicas “Dr. Manuel Quintela”, Montevido Uruguay and the Clinical Research Institute of Montreal
*
Clinical Research Institute of Montreal, 110 Pine Avenue West, Montreal, Quebec, Canada, H2W IR7
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Six patients with Friedreich's ataxia, 4 males and 2 females, their ages ranging from 13 to 33 years, were studied. The early manifestations started between age 7 and 13 with an evolution time between 6 and 20 years. Serial visual and brain stem auditory evoked potential recordings were made. A progressive increase in latency, reduction in amplitude and in latency inter-ocular difference of PlOO were observed. The pattern of the reversal checker-board visual evoked potential was preserved. A disorganized BAEP pattern, a well defined potential I, a very small potential V and a delay in the interpeak latency were constant findings. The assumption is made of a progressive involvement of both visual and central auditory pathways. Pathophysiological mechanisms are discussed.

Type
b—Clinical Physiology and Pathology
Information
Canadian Journal of Neurological Sciences , Volume 11 , Issue S4 , November 1984 , pp. 565 - 569
Copyright
Copyright © Canadian Neurological Sciences Federation 1984

References

Barbeau, A, (1976). Friedreich’s ataxia 1976. An overview. Can J Neurol Sci 3: 389–397.CrossRefGoogle ScholarPubMed
Boudin, G, Grossiord, A, Guillard, A, Milol, J, Lacert, P (1972). Maladie de Friedreich avec atteintes systématisées sus-médullaires. Rev Neurol 127: 444–456.Google Scholar
Chacko, LW (1948). Analysis of fibre-size in human optic nerve. Brit J.ofOphthal 32: 457–461.CrossRefGoogle ScholarPubMed
Carrol, WM, Kriss, A, Baraitser, M, Barrett, G, Halliday, AM (1980). The incidence and nature of visual pathway involvement in Friedreich’s ataxia. Brain 103: 413–434. CrossRefGoogle Scholar
Gilroy, J, Lynn, GE (1978). Computerized tomography and auditory evoked potentials. Arch Neurol (Chic) 35: 143–147. CrossRefGoogle ScholarPubMed
Hughes, JT, Brownell, B, Hewer, RL (1968). The peripheral sensory pathway in Friedreich’s ataxia: an examination by light and electron microscopy of the posterior nerve roots, posterior root ganglia and peripheral sensory nerves in cases of Friedreich’s ataxia. Brain 91 : 803–818.CrossRefGoogle ScholarPubMed
Jones, SJ, Baraitser, M, Halliday, AM (1980). Peripheral and central somatosensory nerve conduction defect in Friedreich’s ataxia. J Neurol Neurosurg Psychiat 43: 495–503.CrossRefGoogle ScholarPubMed
Noel, P, Desmedì, JE (1980). Cerebral and far-field somatosensory evoked potentials in neurological disorders involving the cervical spinal cord, brain-stem thalamus and cortex, in: Desmedt, JE, (ed), Clinical Uses of Cerebral, Brain-Stem and Spinal Somatosensory Evoked Potentials, Basel, Karger, Progr Clin Neurophysiol vol 7, pp 205–230.Google Scholar
Oppenheimer, DR (1976). Diseases of the basal ganglia, cerebellum and motor neurones, in: Blackwood, W and Corsallis, JAN (eds), Greenfield’s Neuropathology, 3rd edition, London, Edward Arnold, pp 626–629.Google Scholar
Pedersen, L, Trojaborg, W (1981). Visual, auditory and somatosensory pathway involvement in hereditary cerebellar ataxia, Friedreich’s ataxia and familial spastic paraplegia. Electroencephal and Clin Neurophysiol 52: 283–297.CrossRefGoogle ScholarPubMed
Satya-Murti, S, Cacace, A, Hanson, P (1980). Auditory dysfunction in Friedreich’s ataxia: result of spiral ganglion degeneration. Neurology (Minn) 30: 1047–1053.CrossRefGoogle ScholarPubMed
Urich, H, Norman, RM, Lloyd, OC (1957). Suprasegmental lesions in Friedreich’s ataxia. Confinia Neurologica 17: 360–371.CrossRefGoogle ScholarPubMed