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Visual Loss Secondary to a Giant Aneurysm in a Patient with Tuberous Sclerosis

Published online by Cambridge University Press:  18 September 2015

Mark Guttman
Affiliation:
Department of Neurology, St. Michael’s Hospital, Toronto, Ontario
S. Mark Tanen
Affiliation:
Department of Neurology, St. Michael’s Hospital, Toronto, Ontario
Colin D. Lambert*
Affiliation:
Department of Neurology, St. Michael’s Hospital, Toronto, Ontario
*
St. Michael’s Hospital30 Bond Street, Toronto, Ontario, Canada M5B 1W8
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Abstract

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We report a fifty three year old man who presented with progressive visual loss. Investigation disclosed a giant aneurysm with optic nerve compression, which was successfully treated surgically. The patient had typical skin lesions of tuberous sclerosis, but did not suffer from a seizure disorder or mental retardation. In the past he had had an enucleation for glaucoma secondary to a retinal phakoma.

Cerebral aneurysms are discussed in relation to the tuberous sclerosis disease process. After review of the literature, we propose that the aneurysms are secondary to dysplastic change in the vessel walls, this is in keeping with the abnormal tissue proliferations in this disease.

Type
Original Articles
Copyright
Copyright © Canadian Neurological Sciences Federation 1984

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