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Review of Clay-Drug Hybrid Materials for Biomedical Applications: Administration Routes

Published online by Cambridge University Press:  01 January 2024

Myung Hun Kim ,
Goeun Choi ,
Ahmed Elzatahry ,
Ajayan Vinu ,
Young Bin Choy  and
Jin-Ho Choy
Myung Hun Kim
Affiliation:
Center for Intelligent Nano-Bio Materials (CINBM), Department of Chemistry and Nano Science, Ewha Womans University, Seoul, 03760, Republic of Korea Interdisciplinary Program in Bioengineering, College of Engineering, Seoul National University, Seoul, 08826, Republic of Korea
Goeun Choi
Affiliation:
Center for Intelligent Nano-Bio Materials (CINBM), Department of Chemistry and Nano Science, Ewha Womans University, Seoul, 03760, Republic of Korea
Ahmed Elzatahry
Affiliation:
Department of Chemistry, King Saud University, 2455 Riyadh 11451, Kingdom of Saudi Arabia Materials Science and Technology Program, College of Arts and Science, Qatar University, 2713, Doha, Qatar
Ajayan Vinu
Affiliation:
Future Industries Institute, University of South Australia, Mawson Lakes, SA, Australia
Young Bin Choy
Affiliation:
Interdisciplinary Program in Bioengineering, College of Engineering, Seoul National University, Seoul, 08826, Republic of Korea Department of Biomedical Engineering, College of Medicine and Institute of Medical & Biological Engineering, Medical Research Center, Seoul National University, Seoul, 03080, Republic of Korea
Jin-Ho Choy*
Affiliation:
Center for Intelligent Nano-Bio Materials (CINBM), Department of Chemistry and Nano Science, Ewha Womans University, Seoul, 03760, Republic of Korea Future Industries Institute, University of South Australia, Mawson Lakes, SA, Australia
*
*E-mail address of corresponding author: jhchoy@ewha.ac.kr
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Abstract

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Focus here is placed on the pharmaceutical and biomedical applications of novel clay-drug hybrid materials categorized by methods of administration. Clay minerals have been used for many years as pharmaceutical and medicinal ingredients for therapeutic purposes. A number of studies have attempted to explore clay-drug hybrid materials for biomedical applications with desired functions, such as sustained release, increased solubility, enhanced adsorption, mucoadhesion, biocompatibility, targeting, etc. The present review attempts not only to summarize the state-of-the-art of clay-drug hybrid materials and their advantages, depending on the methods of administration, but also to deal with challenges and future perspectives of clay mineral-based hybrids for biomedical applications.

Keywords

Administration MethodsBiocompatibilityBiomedical ApplicationsClay-drug HybridMucoadhesionPharmaceutical ApplicationsSustained ReleaseTargeting
Type
Article
Information
Clays and Clay Minerals , Volume 64 , Issue 2 , April 2016 , pp. 115 - 130
Copyright
Copyright © The Clay Minerals Society 2016

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