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The Role of L-Methylfolate in Depressive Disorders

Published online by Cambridge University Press:  07 November 2014

Andrew Farah
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Extract

Major depressive disorder (MDD) is a debilitating illness affecting 7% to 12% of men and 20% to 25% of women. It is usually a recurrent illness, with up to 30% of patients experiencing a depressive episode lasting over 2 years. Depression may also increase the morbidity and mortality of numerous medical conditions, such as cardiac disease, myocardial infarction, chronic pain, diabetes, cerebrovascular events, and respiratory illnesses. The goal of antidepressant therapy is to achieve full remission and functional recovery, and continuing treatment beyond the acute phase is usually necessary to maintain remission. In contrast with full remission, individuals who experience residual symptoms, however mild, have a higher chance of experiencing one or more additional episodes.

Type
Expert Review Supplement
Information
CNS Spectrums , Volume 14 , Issue S2: The Role of L-Methylfolate in Depressive Disorders , January 2009 , pp. 2 - 7
Copyright
Copyright © Cambridge University Press 2009

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