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History and Prevalence of Involuntary Emotional Expression Disorder

Published online by Cambridge University Press:  07 November 2014

John E. Duda
John E. Duda*
Affiliation:
Dr. Duda is co-director of the Parkinson's Disease Research, Education and Clinical Center (PADRECC) of the Philadelphia VA Medical Center, and assistant professor of neurology at the, University of Pennsylvania
*
Parkinson's Disease Research, Education and Clinical Center, Philadelphia VA Medical Center, Philadelphia, PA 19104. Tel: 215-823-5934; Fax:, 215-823-5818; Email:, john.duda@med.va.gov
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Abstract

The syndrome now known as involuntary emotional expression disorder (IEED) is a condition characterized by uncontrollable episodes of laughing and/or crying. It has been known for more than a century, but confusing and conflicting terminology may have hampered the progress of physicians in recognizing this condition. IEED is associated with various neurological disorders and neurodegenerative diseases, including amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, Alzheimer's disease and other dementias, and neurological injuries such as stroke and traumatic brain injury. It is hoped that better defined terminology for IEED may help in the future diagnosis of this debilitating condition, the establishment of accurate prevalence rates for IEED in the varying underlying conditions, and also in removing blame and stigma from sufferers by providing reassurance about the nature of their condition.

Type
Research Article
Information
CNS Spectrums , Volume 12 , Issue S5 , 2007 , pp. 6 - 10
Copyright
Copyright © Cambridge University Press 2007

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References

1. Hipocrates. On the Sacred Disease. 4th Century BC.Google Scholar
2.Damasio, AR. Descartes Error: Emotion, Reason and the Human Brain. New York, NY: Putnam; 1994.Google Scholar
3.Dark, FL, McGrath, JJ, Ron, MA. Pathological laughing and crying. Aust N Z J Psychiatry. 1996;30:472–479.CrossRefGoogle ScholarPubMed
4.Green, RL, Bernat, JL. Pathologic crying. In: Joseph, AB, Young, RR, eds. Movement disorders in Neurology and Neuropsychiatry. Oxford: Blackwell Science; 1999.Google Scholar
5.Wild, B, Rodden, FA, Rapp, A, et al.Humor and smiling: cortical regions selective for cognitive, affective, and volitional components. Neurology. 2006;66:887–893.CrossRefGoogle ScholarPubMed
6.Magnus, A. Fall von Aufhebung des Willenseinflusses auf einige Hirnnerven. In: Müllers Archiv für Anatomie, Physiologie und wissenschaftliche Medicin., eds. 1837:258–266.Google Scholar
7.Darwin, C. The Expression of the Emotions in Man and Animals. New York & London: D Appleton and Company; 1872.CrossRefGoogle Scholar
8.Brissaud, E. Lecons sur les Maladies Nerveuses. Paris: Masson; 1895.Google Scholar
9.Féré, C. Le fou rire prodromique. Rev Neurol (Paris). 1903;11:353–358.Google Scholar
10.Giannuli, A. Ann Istit Psich Univ Roma. iv, 213. 1905.Google Scholar
11.Weisenberg, T. Report of three cases with necropsy and of three cases without necropsy. Univ Penn Medical Bull. 1905:1–39.Google Scholar
12.Wilson, SAK. Some problems in neurology.  No. II. - Pathological laughing and crying. J Neurol Psychopathol. 1924;IV:299–333.CrossRefGoogle Scholar
13.Parvizi, J, Anderson, SW, Martin, CO, Damasio, H, Damasio, AR. Pathological laughter and crying. A link to the cerebellum. Brain. 2001;124:1708–1719.CrossRefGoogle ScholarPubMed
14.Cummings, JL, Arciniegas, DB, Brooks, BR, et al.Defining and diagnosing involuntary emotional expression disorder. CNS Spectr. 2006;11:1–7.CrossRefGoogle ScholarPubMed
15.Arciniegas, DB, Lauterbach, EC, Anderson, KE, et al.The differential diagnosis of pseudobulbar affect (PBA). Distinguishing PBA among disorders of mood and affect. Roundtable monograph supplement. CNS Spectr. 2005;10:1–14.CrossRefGoogle Scholar
16.Feinstein, A, Feinstein, K, Gray, T, O'Connor, P. Prevalence and neurobehavioral correlates of pathological laughing and crying in multiple sclerosis. Arch Neurol. 1997;54:1116–1121.CrossRefGoogle ScholarPubMed
17.Poeck, K. Pathophysiology of emotional disorders associated with brain damage. In: Disorders of Emotion, eds. 1969:343–367.Google Scholar
18.House, A, Dennis, M, Molyneux, A, Warlow, C, Hawton, K. Emotionalism after stroke. BMJ. 1989;298:991–994.CrossRefGoogle ScholarPubMed
19.Keller, R, Torta, R, Lagget, M, Crasto, S, Bergamasco, B. Psychiatric symptoms as late onset of Wilson's disease: neuroradiological findings, clinical features and treatment. Ital J Neurol Sci. 1999;20:49–54.CrossRefGoogle ScholarPubMed
20.Robinson, RG, Parikh, RM, Lipsey, JR, Starkstein, SE, Price, TR. Pathological laughing and crying following stroke: validation of a measurement scale and a double-blind treatment study. Am J Psychiatry. 1993;150:286–293.Google Scholar
21.Soueif, MI. Chronic cannabis takers: some temperamental characteristics. Drug Alcohol Depend. 1975;1:125–154.CrossRefGoogle ScholarPubMed
22.Hobi, V, Ladewig, D, Dubach, UC, Miest P-C, Ehrensberger, T. Analgesic abuse and personality characteristics. Int J Clin Pharmacol Biopharm. 1976;13:36–41.Google ScholarPubMed
23.Koufen, H, Dichgans, J. [Similarities and differences after head injuries in children and adults (author's transl)]. Med Klin. 1977;72:739–743.Google ScholarPubMed
24.Lieberman, A, Benson, DF. Control of emotional expression in pseudobulbar palsy. A personal experience. Arch Neurol. 1977;34:717–719.CrossRefGoogle ScholarPubMed
25.Sloan, RL, Brown, KW, Pentland, B. Fluoxetine as a treatment for emotional lability after brain injury. Brain Inj. 1992;6:315–319.CrossRefGoogle ScholarPubMed
26.Levinson, B, Wright, P, Barklem, S. Effect of buflomedil on behaviour, memory, and intellectual capacity in patients with dementia. A placebo-controlled study. S Afr Med J. 1985;68:302–307.Google ScholarPubMed
27.Schiffer, RB, Cash, J, Herndon, RM. Treatment of emotional lability with low-dosage tricyclic antidepressants. Psychosomatics. 1983;24:1094–1096.CrossRefGoogle ScholarPubMed
28.Seliger, GM, Hornstein, A, Flax, J, Herbert, J, Schroeder, K. Fluoxetine improves emotional incontinence. Brain Inj. 1992;6:267–270.CrossRefGoogle ScholarPubMed
29.Wolf, JK, Santana, HB, Thorpy, M. Treatment of “emotional incontinence” with levodopa. Neurology. 1979;29:1435–1436.CrossRefGoogle ScholarPubMed
30.Sandyk, R. Nomifensine for “emotional incontinence” of the pseudobulbar type. J Am Geriatr Soc. 1985;33:375.CrossRefGoogle ScholarPubMed
31.Arciniegas, DB, Topkoff, J. The neuropsychiatry of pathologic affect: an approach to evaluation and treatment. Semin Clin Neuropsychiatry. 2000;5:290–306.CrossRefGoogle ScholarPubMed
32.Brooks, BR, Thisted, RA, Appel, SH, et al.Treatment of pseudobulbar affect in ALS with dextromethorphan/quinidine: a randomized trial. Neurology. 2004;63:1364–1370.CrossRefGoogle ScholarPubMed
33.Okun, MS, Riestra, AR, Nadeau, SE. Treatment of ballism and pseudobulbar affect with sertraline. Arch Neurol. 2001;58:1682–1684.CrossRefGoogle ScholarPubMed
34.Okuda, DT, Chyung, AS, Chin, CT, Waubant, E. Acute pathological laughter. Mov Disord. 2005;20:1389–1390.CrossRefGoogle ScholarPubMed
35.Schiffer, R, Pope, LE. Review of pseudobulbar affect including a novel and potential therapy. J Neuropsychiatry Clin Neurosci. 2005;17:447–454.CrossRefGoogle ScholarPubMed
36.Starkstein, SE, Migliorelli, R, Tesón, A, et al.Prevalence and clinical correlates of pathological affective display in Alzheimer's disease. J Neurol Neurosurg Psychiatry. 1995;59:55–60.CrossRefGoogle ScholarPubMed
37.Gubbay, SS, Kahana, E, Zilber, N, Cooper, G, Pintov, S, Leibowitz, Y. Amyotrophic lateral sclerosis. A study of its presentation and prognosis. J Neurol. 1985;232:295–300.CrossRefGoogle ScholarPubMed
38.Caroscio, JT, Mulvihill, MN, Sterling, R, Abrams, B. Amyotrophic lateral sclerosis. Its natural history. Neurol Clin. 1987;5:1–8.CrossRefGoogle ScholarPubMed
39.Minden, SL, Schiffer, RB. Affective disorders in multiple sclerosis. Review and recommendations for clinical research. Arch Neurol. 1990;47:98–104.CrossRefGoogle ScholarPubMed
40.Zeilig, G, Drubach, DA, Katz-Zeilig, M, Karatinos, J. Pathological laughter and crying in patients with closed traumatic brain injury. Brain Inj. 1996;10:591–597.CrossRefGoogle ScholarPubMed
41.Tateno, A, Jorge, RE, Robinson, RG. Pathological laughing and crying following traumatic brain injury. J Neuropsychiatry Clin Neurosci. 2004;16:426–434.CrossRefGoogle ScholarPubMed
42.Tang, WK, Chan, SSM, Chiu, HFK, et al.Emotional incontinence in Chinese stroke patients. Diagnosis, frequency, and clinical and radiological correlates. J Neurol. 2004;251:865–869.CrossRefGoogle ScholarPubMed
43.Kim, JS, Choi, S, Kwon, SU, Seo, YS. Inability to control anger or aggression after stroke. Neurology. 2002;58:1106–1108.CrossRefGoogle ScholarPubMed
44.Gallagher, JP. Pathologic laughter and crying in ALS: a search for their origin. Acta Neurol Scand. 1989;80:114–117.CrossRefGoogle Scholar
45.Shaibani, AT, Sabbagh, MN, Doody, R. Laughter and crying in neurologic disorders. Neuropsychiatry Neuropsychol Behav Neurol. 1994;7:243–250.Google Scholar
46.Morris, PL, Robinson, RG, Raphael, B. Emotional lability after stroke. Aust N Z J Psychiatry. 1993;27:601–605.CrossRefGoogle ScholarPubMed
47.Houeto, JL, Mesnage, V, Mallet, L, et al.Behavioural disorders, Parkinson's disease and subthalamic stimulation. J Neurol Neurosurg Psychiatry. 2002;72:701–707.CrossRefGoogle ScholarPubMed
48.Kaschka, WP, Meyer, A, Schier, KR, Froscher, W. Treatment of pathological crying with citalopram. Pharmacopsychiatry. 2001;34:254–258.CrossRefGoogle ScholarPubMed
49.Lader, M, Pétursson, H. Psychiatric disorders. In: Girdwood, RH, Petrie, JC, eds. Textbook of Medical Treatment. Edinburgh: Churchill Livingstone; 1987:285–301.Google Scholar