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Narcolepsy

Published online by Cambridge University Press:  07 November 2014

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Jerome M. Siegel, PhD, is professor of psychiatry at the University of California, Los Angeles, former president of the Sleep Research Society, and the recipient of Merit and Javits awards from the National Institutes of Health and the Distinguished Scientist award from the Sleep Research Society. His laboratory has made discoveries concerning the role of hypocretin in human narcolepsy and Parkinson's disease. He has studied the phylogeny of sleep as a clue to sleep function, discovering that the primitive mammal platypus has rapid eye movement sleep and that marine mammals can go without extended periods of sleep for long periods without ill effects.

Type
In Session
Information
CNS Spectrums , Volume 14 , Issue 6 , June 2009 , pp. 295 - 297
Copyright
Copyright © Cambridge University Press 2009

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References

REFERENCES

1.Thannickal, TC, Lai, YY, Siegel, JM. Hypocretin (orexin) cell loss in Parkinson's disease. Brain. 2007;130(Pt 6):1586–1595.Google Scholar
2.Deadwyler, SA, Porrino, L, Siegel, JM, Hampson, RE. Systemic and nasal delivery of orexin-A (Hypocretin-1) reduces the effects of sleep deprivation on cognitive performance in nonhuman primates. J Neurosci. 2007;27(52):14239–14247.Google Scholar