Hostname: page-component-78c5997874-4rdpn Total loading time: 0 Render date: 2024-11-14T04:43:09.576Z Has data issue: false hasContentIssue false
  • English
  • Français

Somnambulism Induced by Quetiapine: Two Case Reports and a Review of the Literature

Published online by Cambridge University Press:  07 November 2014

Zeba Hasan Hafeez  and
Constance M. Kalinowski
Get access Rights & Permissions [Opens in a new window]

Abstract

Somnambulism, a previously unreported side effect of quetiapine, is described in two cases. Both cases involved individuals who had no prior or family history of somnambulism and had attention-deficit/hyperactivity disorder. The possible significance of this will also be discussed. Somnambulism is a common parasomnia that reflects an impairment in the normal mechanisms of arousal from sleep in which motor behaviors are activated without full consciousness. Motor behaviors are initiated during deep non-rapid eye movement or slow-wave sleep (stages 3-4), and may be limited to relatively simple manifestations, such as sitting up, fumbling with objects or bedclothes, or mumbling.

Type
Case Report
Information
CNS Spectrums , Volume 12 , Issue 12 , December 2007 , pp. 910 - 912
Copyright
Copyright © Cambridge University Press 2007

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1.Bassetti, C, Velia, S, Donati, F, Wielepp, P, Weder, B. SPECT during sleepwalking. Lancet. 2000;356:484–485.CrossRefGoogle ScholarPubMed
2.Huapaya, LV. Seven cases of somnambulism induced by drugs. Am J Psychiatry. 1979;136:985–986.Google ScholarPubMed
3.Kolivakis, TT, Margolese, HC, Beauclair, L, Chouinard, G. Olanzapine-induced somnambulism. Am J Psychiatry. 2001:158:1158.CrossRefGoogle ScholarPubMed
4.Salin-Pascual, RJ, Herrera-Estrella, M, Galicia-Polo, L, Laurrabaqulo, MR. Olanzapine acute administration in schizophrenic patients increases delta sleep and sleep efficiency. Biol Psychiatry. 1999:46:141–143.CrossRefGoogle ScholarPubMed
5.Sharpley, AL, Vassallo, CM, Cowen, PJ. Olanzapine increases slow-wave sleep: evidence for blockade of central 5-HT2C receptors in vivo. Biol Psychiatry. 2000;47:468–470.CrossRefGoogle Scholar
6.Khazaal, Y, Krenz, S, Zullino, DF. Bupropion-induced somnambulism. Addict Biol. 2003;8:359–362.CrossRefGoogle ScholarPubMed
7.Yang, W, Dollear, M, Muthukrishnan, SR. One rare side effect of zolpidem-sleep-walking: a case report. Arch Phys Med Rehabil. 2005:86:1265–1266.CrossRefGoogle ScholarPubMed
8.Yanes Baonza, M, Ferrer García-Barras, JM, Cabrera Majada, A, Sánchez González, R. Sleep-walking linked to Zolpidem. Aten Primaria. 2003:32:438.CrossRefGoogle ScholarPubMed
9.Sharma, A, Dewan, VK. A case report of zolpidem-induced somnambulism. J Clin Psychiatry. 2005:7:74.Google ScholarPubMed
10.Harazin, J, Berigan, TR. Zolpidem tartrate and somnambulism. Mil Med. 1999;164:669–670.CrossRefGoogle ScholarPubMed
11.Sattar, SP, Ramaswamy, S, Bhatia, SC. Petty, F. Somnambulism due to probable Interaction of valproic acid and Zolpidem. Ann Pharmacother. 2003:37:1429–1433.CrossRefGoogle ScholarPubMed
12.Varkey, BM, Varkey, LM. Topiramate induced somnabulism and automatic behavior. Indian J Med Sci. 2003;57:508–510.Google Scholar
13.Landry, P, Montplaisir, J. Lithium-induced somnambulism. Can J Psychiatry. 1998;43:957–958.Google ScholarPubMed
14.Trulson, ME, Jacobs, BL, Morrison, AR. Raphe unit activity during REM sleep in normal cats and in pontine lesioned cats displaying REM sleep without atonia. Brain Res. 1981;226:75–91.CrossRefGoogle ScholarPubMed
15.Steinfels, GF, Heym, J, Strecker, RE, Jacobs, BL. Raphe unit activity in freely moving cats is altered by manipulation of central but not peripheral motor systems. Brain Res. 1983;279:77–84.CrossRefGoogle Scholar
16.Juszczak, GR, Swiergiel, AH. Serotonergic hypothesis of sleepwalking. Med Hypotheses. 2005;64:28–32.CrossRefGoogle ScholarPubMed
17.Wang, W, Bradley, SR, Richerson, GB. Quantification of the response of rat medullary raphe neurons to independent changes in pH(0) and P(C02). J Physiol. 2002;540:951–970.CrossRefGoogle Scholar
18.Kales, JD, Kales, A, Soldates, CR, Chamberlin, K, Martin, ED. Sleepwalking and night terrors related to febrile illness. Am J Psychiatry. 1979;136:1214–1215.Google ScholarPubMed
19.Wegener, G, Bandpey, Z, Heiberg, IL, Mork, A, Rosenberg, R. Increased extracellular serotonin level in rat hippocampus induced by chronic Citalopram is augmented by subchronic lithium: neurochemical and behavioural studies in the rat. Psychopharmacol. 2003;166:188–194.CrossRefGoogle ScholarPubMed
20.Price, LH, Charney, DS, Delgado, PL, Heninger, GR. Lithium and serotonin function: implications for the serotonin hypothesis of depression. Psychopharmacology (Berl). 1990;100:3–12.CrossRefGoogle ScholarPubMed
21.Tharoor, H, Lobos, EA, Todd, RD, Reiersen, AM. Association of dopamine, serotonin, and nicotinic gene polymorphisms with methylphenidate response In ADHD. Am J Med Genet B Neuropsychiatr Genet. 2007 Oct 19; [Epub ahead of print].Google Scholar
22.Sheehan, K, Lowe, N, Kirley, A, et al.Tryptophan hydroxylase 2 (TPH2) gene variants associated with ADHD. Mol Psychiatry. 2005;10:944–949.CrossRefGoogle ScholarPubMed
23.Li, J, Wang, Y, Zhou, R, et al.Association between tryptophan hydroxylase gene polymorphisms and attention deficit hyperactivity disorder in Chinese Han population. Am J Med Genet B Neuropsychiatr Genet. 2006;141:126–129.CrossRefGoogle Scholar