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Treatment-Refractory Schizoaffective Disorder in a Patient with Dyke-Davidoff-Masson Syndrome

Published online by Cambridge University Press:  07 November 2014

Benedikt Amann ,
Celia García de la Iglesia ,
Peter McKenna ,
Edith Pomarol-Clotet ,
Marisa Sanchez-Guerra  and
Michael Orth
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Abstract

Dyke-Davidoff-Masson syndrome, or cerebral hemiatrophy, is a pre- or perinatally acquired entity characterized by predominantly neurologic symptoms, such as seizures, facial asymmetry, contralateral hemiplegia, and mental retardation. Psychiatric symptoms are rarely reported. We report the first case of left cerebral hemiatrophy and a late onset of treatment-resistant schizoaffective disorder after a stressful life event. The patient finally responded well to clozapine. The clinical history and results from structural neuroimaging are highlighted to discuss the possible developmental bias for psychotic disorders.

Type
Case Report
Information
CNS Spectrums , Volume 14 , Issue 1 , January 2009 , pp. 36 - 40
Copyright
Copyright © Cambridge University Press 2009

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