Hostname: page-component-cd9895bd7-7cvxr Total loading time: 0 Render date: 2024-12-25T19:32:19.448Z Has data issue: false hasContentIssue false

Zinc Sulfate Could be a Potential Agent for the Treatment of Huntington's Disease Through Activating Central TrkB Signaling

Published online by Cambridge University Press:  07 November 2014

Rights & Permissions [Opens in a new window]

Abstract

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Letter to the Editor
Copyright
Copyright © Cambridge University Press 2010

References

REFERENCES

1.Zuccato, C, Cattaneo, E. Role of brain-derived neurotrophic factor in Huntington's disease. Prog Neurobiol. 2007; 81: 294330.CrossRefGoogle ScholarPubMed
2.Ferrer, I, Goutan, E, Marín, C, Rey, MJ, Ribalta, T. Brain-derived neurotrophic factor in Huntington disease. Brain Res. 2000; 866: 257261.Google Scholar
3.Ginés, S, Bosch, M, Marco, S, et al. Reduced expression of the TrkB receptor in Huntington's disease mouse models and in human brain. Eur J Neurosci. 2006; 23: 649658.Google Scholar
4.Borrell-Pagès, M, Canals, JM, Cordelières, FP, et al. Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase. J Clin Invest. 2006; 116: 14101424.Google Scholar
5.Kells, AP, Fong, DM, Dragunow, M, et al. AAV-mediated gene delivery of BDNF or GDNF is neuroprotective in a model of Huntington disease. Mol Ther. 2004; 9: 682688.Google Scholar
6.Bilici, M, Yildirim, F, Kandil, S, et al. Double-blind, placebo-controlled study of zinc sulfate in the treatment of attention deficit hyperactivity disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2004; 28: 181190.Google Scholar
7.Siwek, M, Dudek, D, Paul, IA, et al. Zinc supplementation augments efficacy of imipramine in treatment resistant patients: A double blind, placebo-controlled study. J Affect Disord. In press.Google Scholar
8.Nowak, G, Legutko, B, Szewczyk, B, et al. Zinc treatment induces cortical brain-derived neurotrophic factor gene expression. Eur J Pharmacol. 2004; 492: 5759.Google Scholar
9.Hwang, JJ, Park, MH, Choi, SY, Koh, JY. Activation of the Trk signaling pathway by extracellular zinc. Role of metalloproteinases. J Biol Chem. 2005; 280: 1199512001.Google Scholar
10.Sowa-Kuma, M, Legutko, B, Szewczyk, B, et al. Antidepressant-like activity of zinc: further behavioral and molecular evidence. J Neural Transm. 2008; 115: 16211628.Google Scholar
11.Franco, JL, Posser, T, Brocardo, PS, et al. Involvement of glutathione, ERK1/2 phosphorylation and BDNF expression in the antidepressant-like effect of zinc in rats. Behav Brain Res. 2008; 188: 316323.Google Scholar