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3D Simulations of Blood Flow Dynamics in Compliant Vessels: Normal, Aneurysmal, and Stenotic Arteries

Part of: Incompressible viscous fluids Physiological, cellular and medical topics

Published online by Cambridge University Press:  17 May 2016

Yongsam Kim ,
Yunyoung Park  and
Sookkyung Lim
Yongsam Kim*
Affiliation:
Department of Mathematics, Chung-Ang University, Dongjakgu Heukseokdong, Seoul 156-756, Korea
Yunyoung Park*
Affiliation:
Department of Mathematics, Chung-Ang University, Dongjakgu Heukseokdong, Seoul 156-756, Korea
Sookkyung Lim*
Affiliation:
Department of Mathematical Sciences, University of Cincinnati, Cincinnati, Ohio, 45242, USA
*
*Corresponding author. Email addresses:kimy@cau.ac.kr (Y. Kim), yunypark@cau.ac.kr (Y. Park), sookkyung.lim@uc.edu (S. Lim)
*Corresponding author. Email addresses:kimy@cau.ac.kr (Y. Kim), yunypark@cau.ac.kr (Y. Park), sookkyung.lim@uc.edu (S. Lim)
*Corresponding author. Email addresses:kimy@cau.ac.kr (Y. Kim), yunypark@cau.ac.kr (Y. Park), sookkyung.lim@uc.edu (S. Lim)
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Abstract

Arterial diseases such as aneurysm and stenosis may result from the mechanical and/or morphological change of an arterial wall structure and correspondingly altered hemodynamics. The development of a 3D computational model of blood flow can be useful to study the hemodynamics in major blood vessels and may provide an insight into the noninvasive technique to detect arterial diseases in early stage. In this paper, we present a three-dimensional model of blood flow in the aorta, which is based on the immersed boundary method to describe the interaction of blood flow with the aortic wall. Our simulation results show that the hysteresis loop is evident in the pressure-diameter relationship of the normal aorta when the arterial wall is considered to be viscoelastic. In addition, it is shown that flow patterns and pressure distributions are altered in response to the change of aortic morphology.

Keywords

Blood flowimmersed boundary methodcompliant vesselaortic aneurysmaortic stenosis

MSC classification

Secondary: 76D05: Navier-Stokes equations 92C35: Physiological flow
Type
Research Article
Information
Communications in Computational Physics , Volume 19 , Issue 5 , May 2016 , pp. 1167 - 1190
Copyright
Copyright © Global-Science Press 2016 

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