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Emotion dysregulation and the development of borderline personality disorder

Published online by Cambridge University Press:  12 December 2005

KATHERINE M. PUTNAM  and
KENNETH R. SILK
KATHERINE M. PUTNAM
Affiliation:
National Center for PTSD, Boston Boston University Medical Center
KENNETH R. SILK
Affiliation:
University of Michigan Health System
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Abstract

We review the role of emotion regulation in borderline personality disorder (BPD). We briefly discuss the historical development of BPD as a disorder where emotional regulation plays a key role. We review the concept of emotion regulation in general and explore both one-factor and two-factor models of emotion regulation. We discuss cognitive and attentional aspects of emotion regulation, and explore these regulatory controls as operating as both voluntary as well as automatic processes. We then turn to other neurophysiological models of emotion regulation in general and examine how those models, both neurophysiologically and neuroanatomically, are expressed in individuals with BPD. We examine how neuroimaging, both anatomical and functional, reveals the roles that various neuroanatomical structures play in the regulation of emotion in BPD. We conclude by creating a neurodevelopmental model that describes how a complex matrix involving the interplay of constitutional/biological predispositions with environmental stressors as well as with parental effectiveness in response to the child's emotion expression can impact key aspects of adult cognitive, affective, interpersonal, and behavioral functioning that culminate in a diagnosis of BPD.

Type
Research Article
Information
Development and Psychopathology , Volume 17 , Issue 4 , December 2005 , pp. 899 - 925
Copyright
© 2005 Cambridge University Press

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References

REFERENCES

Ainsworth, M. D., Bell, S. M., & Stayton, D. J. (1971). Individual differences in strange situation behaviour of one-year olds. In H. R. Schaeffer (Ed.), The origins of human social relations (pp. 17–57). London: Academic Press.
Aldwin, C. M., Levenson, M. R., & Spiro, A. (1994). Vulnerability and resilience to combat exposure: Can stress have lifelong effects? Psychology and Aging 9, 34–44.Google Scholar
American Psychiatric Association. (1980). Diagnostic and statistical manual of mental disorders (3rd ed.). Washington, DC: Author.
American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed., text revision). Washington, DC: Author.
Arango, V., Underwood, M. D., Gubbi, A. V., & Mann, J. J. (1995). Localized alterations in pre- and postsynaptic serotonin binding sites in the ventrolateral prefrontal cortex of suicide victims. Brain Research 688, 121–133.CrossRefGoogle Scholar
Arntz, A., Appels, C., & Sieswerda, S. (2000). Hypervigilance in borderline disorder: A test with the emotional Stroop paradigm. Journal of Personality Disorders 14, 366–373.CrossRefGoogle Scholar
Asberg, M. (1997). Neurotransmitters and suicidal behavior. The evidence from cerebrospinal fluid studies. Annals of the New York Academy of Sciences 836, 158–181.CrossRefGoogle Scholar
Auerbach, J., Geller, V., Lezer, S., Shinwell, E., Belmaker, R. H., Levine, J., & Ebstein, R. P. (1999). Dopamine D4 receptor (D4DR) and serotonin transporter (5-HTTLPR) polymorphisms in the determination of temperament in 2-month-old infants. Molecular Biology 4, 369–373.Google Scholar
Barrett, K. C., & Campos, J. J. (1987). Perspectives on emotional development II: A functionalists approach to emotions. In J. D. Osofsky (Ed.), Handbook of infant development (pp. 555–578). Oxford: Wiley.
Bennett, A. J., Lesch, K. P., Heils, A., Long, J. C., Lorenz, J. G., Shoaf, S. E., et al. (2002). Early experience and serotonin transporter gene variation interact to influence primate CNS function. Molecular Psychiatry 7, 118–122.CrossRefGoogle Scholar
Bishop, S., Duncan, J., Brett, M., & Lawrence, A. D. (2004). Prefrontal cortical function and anxiety: Controlling attention to threat-related stimuli. Nature Neuroscience 7, 184–188.CrossRefGoogle Scholar
Bishop, S. J., Duncan, J., & Lawrence, A. D. (2004). State anxiety modulation of the amygdala response to unattended threat-related stimuli. Journal of Neuroscience 24, 10364–10368.Google Scholar
Bremner, J. D., Narayan, M., Anderson, E. R., Staib, L. H., Miller, H. L., & Charney, D. S. (2000). Hippocampal volume reduction in major depression. American Journal of Psychiatry 157, 115–118.CrossRefGoogle Scholar
Bremner, J. D., Randall, P., Scott, T. M., Bronen, R. A., Seibyl, J. P., Southwick, S. M., et al. (1995). MRI-based measurement of hippocampal volume in patients with combat-related posttraumatic stress disorder. American Journal of Psychiatry 152, 973–981.Google Scholar
Bremner, J. D., Randall, P., Vermetten, E., Staib, L., Bronen, R. A., Mazure, C., et al. (1997). Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse—A preliminary report. Biological Psychiatry 41, 23–32.CrossRefGoogle Scholar
Bremner, J. D., Vermetten, E., Vythilingam, M., Afzal, N., Schmahl, C., Elzinga, B., et al. (2004). Neural correlates of the classic color and emotional Stroop in women with abuse-related posttraumatic stress disorder. Biological Psychiatry 55, 612–620.CrossRefGoogle Scholar
Brown, M. Z., Comtois, K. A., & Linehan, M. M. (2002). Reasons for suicide attempts and non-suicidal self-injury in women with borderline personality disorder. Journal of Abnormal Psychology 111, 198–202.CrossRefGoogle Scholar
Browne, A., & Finkelhor, D. (1986). Impact of child sexual abuse: A review of the literature. Psychological Bulletin 99, 66–77.CrossRefGoogle Scholar
Bush, G., Luu, P., & Posner, M. I. (2000). Cognitive and emotional influences in anterior cingulate cortex. Trends in Cognitive Sciences 4, 215–222.CrossRefGoogle Scholar
Campos, J. J., Campos, R. G., & Barrett, K. C. (1989). Emergent themes in the study of emotional development and emotion regulation. Developmental Psychology 25, 394–402.CrossRefGoogle Scholar
Campos, J. J., Frankel, C. B., & Camras, L. (2004). On the nature of emotion regulation. Child Development 75, 377–394.CrossRefGoogle Scholar
Caspi, A., McClay, J., Moffitt, T. E., Mill, J., Martin, J., Craig, I. W., et al. (2002). Role of the genotype in the cycle of violence in maltreated children. Science 297, 851–854.CrossRefGoogle Scholar
Charney, D. S. (2004). Psychobiological mechanisms of resilience and vulnerability: Implications for successful adaptation to extreme stress. The American Journal of Psychiatry 161, 195–216.CrossRefGoogle Scholar
Cicchetti, D., Ganiban, J., & Barnett, D. (1991). Contributions from the study of high-risk populations to understanding the development of emotion regulation. In J. Garber & K. A. Dodge (Eds.), The development of emotion regulation and dysregulation (pp. 15–48). New York: Cambridge University Press.
Coccaro, E. F., Astill, J. L., Herbert, J. L., & Schut, A. G. (1990). Fluoxetine treatment of impulsive aggression in DSM-III-R personality disorder patients. Journal of Clinical Psychopharmacology 10, 373–375.Google Scholar
Cole, P. M., Martin, S. E., & Dennis, T. A. (2004). Emotion regulation as a scientific construct: Methodological challenges and directions for child development research. Child Development 75, 317–333.CrossRefGoogle Scholar
Cole, P. M., Michel, M. K., & Teti, L. O. (1994). The development of emotion regulation and dysregulation: A clinical perspective. Monographs of the Society for Research in Child Development 59(2–3), 73–100.CrossRefGoogle Scholar
Corrigan, F. M., Davidson, A., & Heard, H. (2000). The role of dysregulated amygdalic emotion in borderline personality disorder. Medical Hypotheses 54, 574–579.CrossRefGoogle Scholar
Davidson, R., & Irwin, W. (1999). The functional neuroanatomy of emotion and affective style. Trends in Cognitive Sciences 3, 11–21.CrossRefGoogle Scholar
Davidson, R. J., Irwin, W., Anderle, M. J., & Kalin, N. H. (2003). The neural substrates of affective processing in depressed patients treated with venlafaxine. American Journal of Psychiatry 160, 64–75.CrossRefGoogle Scholar
Davidson, R. J., Putnam, K. M., & Larson, C. L. (2000). Dysfunction in the neural circuitry of emotion regulation—A possible prelude to violence. Science 289, 591–594.CrossRefGoogle Scholar
De la Fuente, J. M., Goldman, S., Stanus, E., Vizuete, C., Morlan, I., Bobes, J., et al. (1997). Brain glucose metabolism in borderline personality disorder. Journal of Psychiatric Research 31, 531–541.CrossRefGoogle Scholar
Depue, R. A., & Lenzenweger, M. F. (2001). A neurobehavioral dimensional model. In W. J. Livesley (Ed.), Handbook of personality disorders. Theory, research, and treatment (pp. 136–176). New York: Guilford Press.
Depue, R. A., & Lenzenweger, M. F. (2005). A neurobehavioral dimensional model of personality disturbance. In M. F. Lenzenweger & J. F. Clarkin (Eds.). Major theories of personality disorder (2nd ed., pp. 391–453). New York: Guilford Press.
Derryberry, D., & Rothbart, M. K. (1997). Reactive and effortful processes in the organization of temperament. Development and Psychopathology 9, 633–652.Google Scholar
Deutsch, H. (1943). Some forms of emotional disturbance and their relationship to schizophrenia. Psychoanalytic Quarterly 11, 301–321.Google Scholar
Diamond, D., & Doane, J. A. (1994). Disturbed attachment and negative affective style: An intergenerational spiral. British Journal of Psychiatry 164, 770–781.CrossRefGoogle Scholar
Dodge, K. A. (1991). Emotion and social information processing. In J. Garber & K. A. Dodge (Eds.), Development of emotion regulation and dysregulation. New York: Cambridge University Press.
Donegan, N. H., Sanislow, C. A., Blumberg, H. P., Fulbright, R. K., Lacadie, C., Skudlarski, P., et al. (2003). Amygdala hyperreactivity in borderline personality disorder: Implications for emotional dysregulation. Biological Psychiatry 54, 1284–1293.CrossRefGoogle Scholar
Driessen, M., Herrmann, J., Stahl, K., Zwaan, M., Meier, S., Hill, A., et al. (2000). Magnetic resonance imaging volumes of the hippocampus and the amygdala in women with borderline personality disorder and early traumatization. Archives of General Psychiatry 57, 1115–1122.CrossRefGoogle Scholar
Dunn, J., & Brown, J. (1991). Relationships, talk about feelings, and the development of affect regulations in early childhood. In J. Garber & K. A. Dodge (Eds.), Development of emotion regulation and dysregulation (pp. 89–108). New York: Cambridge University Press.
Fan, J., McCandliss, B. D., Sommer, T., Raz, A., & Posner, M. I. (2002). Testing the efficiency and independence of attentional networks. Journal of Cognitive Neuroscience 14, 340–347.CrossRefGoogle Scholar
Frankel, C. B. (1999). Such order from confusion sprung: Adaptive competence and affect regulation (emotion, self-regulation, and coping). Dissertation Abstracts International: Section B: The Sciences & Engineering, 60, 3000.Google Scholar
Frankel, J. (2002). Exploring Ferenczi's concept of identification with the aggressor: It's role is trauma, everyday life, and the therapeutic relationship. Psychoanalytic Dialogues 12, 101–139.CrossRefGoogle Scholar
Frijda, N. H. (1986). The emotions. New York: Cambridge University Press.
Frosch, J. (1964). The psychotic character: Clinical psychiatric considerations. Psychiatric Quarterly 38, 81–96.CrossRefGoogle Scholar
Gabbard, G. O., & Wilkinson, S. M. (1994). Management of countertransference with borderline patients. Washington, DC: American Psychiatric Press.
Gekoski, M. J., Rovee–Collier, C. K., & Carulli–Rabinowitz, V. (Jul 1983). A longitudinal analysis of inhibition and infant distress: The origins of social expectations? Infant Behavior and Development 6, 339–351.Google Scholar
Gerardi–Caulton, G. (2000). Sensitivity to spatial conflict and the development of self-regulation in children 24–36 months of age. Developmental Science 3, 397–404.CrossRefGoogle Scholar
Gross, J. J. (1998a). The emerging field of emotion regulation: An integrative review. Review of General Psychology 2, 271–299.Google Scholar
Gross, J. J. (1998b). Antecedent and response-focused emotion regulation: divergent consequences for experience, expression, and physiology. Journal of Personality and Social Psychology 74, 224–237.Google Scholar
Gross, J. J. (1999). Emotion regulation: Past, present, future. Cognition and Emotion 13, 551–573.CrossRefGoogle Scholar
Gross, J. J., & Levenson, R. W. (1993). Emotional suppression: Physiology, self-report, and expressive behavior. Journal of Personality and Social Psychology 64, 970–986.CrossRefGoogle Scholar
Gross, J. J., & Levenson, R. W. (1997). Hiding feelings: The acute effects of inhibiting negative and positive emotion. Journal of Abnormal Psychology 106, 95–103.CrossRefGoogle Scholar
Gunderson, J. G. (1984). Borderline personality disorder. Washington, DC: American Psychiatric Press.
Gunderson, J. G., & Singer, M. T. (1975). Defining borderline patients: An overview. American Journal of Psychiatry 132, 1–10.Google Scholar
Gurvits, T. V., Shenton, M. E., Hokama, H., Ohta, H., Lasko, N. B., Gilbertson, M. W., et al. (1996). Magnetic resonance imaging study of hippocampal volume in chronic, combat-related posttraumatic stress disorder. Biological Psychiatry 40, 1091–1099.CrossRefGoogle Scholar
Herpertz, S. C., Dietrich, T. M., Wenning, B., Krings, T., Erberich, S. G., Willmes, K., et al. (2001). Evidence of abnormal amygdala functioning in borderline personality disorder: A functional MRI study. Biological Psychiatry 50, 292–298.CrossRefGoogle Scholar
Herpertz, S. C., Kunert, H. J., Schwenger, U. B., & Sass, H. (1999). Affective responsiveness in borderline personality disorder: A psychophysiological approach. American Journal of Psychiatry 156, 1550–1556.CrossRefGoogle Scholar
Hoch, P., & Polatin, P. (1949). Pseudoneurotic forms of schizophrenia. Psychiatric Quarterly 23, 248–276.CrossRefGoogle Scholar
Jackson, D. C., Malmstadt, J. R., Larson, C. L., & Davidson, R. J. (2000). Suppression and enhancement of emotional responses to unpleasant pictures. Psychophysiology 37, 515–522.CrossRefGoogle Scholar
Juengling, F. D., Schmahl, C., Hesslinger, B., Ebert, D., Bremner, J. D., Gostomzyk, J., et al. (2003). Positron emission tomography in female patients with borderline personality disorder. Journal of Psychiatric Research 37, 109–115.CrossRefGoogle Scholar
Kernberg, P. F., Weiner, A. S., & Bardenstein, K. K. (2000). Personality disorders in children and adolescents. New York: Basic Books.
Knight, R. (1953). Borderline states. Bulletin of the Menninger Clinic 17, 1–12.CrossRefGoogle Scholar
Koenigsberg, H. W., Harvey, P. D., Mitropoulou, V., Schmeidler, J., New, A. S., Goodman, M., Silverman, J. M., et al. (2002). Characterizing affective instability in borderline personality disorder. American Journal of Psychiatry 159, 784–788.CrossRefGoogle Scholar
Kopp, C. B. (1989). Regulation of distress and negative emotions: A developmental view. Developmental Psychology 25, 343–354.CrossRefGoogle Scholar
Korfine, L., & Hooley, J. M. (2000). Directed forgetting of emotional stimuli in borderline personality disorder. Journal of Abnormal Psychology 109, 214–221.CrossRefGoogle Scholar
Kurtz, J. E., & Morey, L. C. (1998). Negativism in evaluative judgments of words among depressed outpatients with borderline personality disorder. Journal of Personality Disorders 12, 351–361.CrossRefGoogle Scholar
Lamb, M. E., & Malkin, C. M. (1986). The development of social expectations in distress-relieve sequences: A longitudinal study. International Journal of Behavioral Development 9, 235–249.CrossRefGoogle Scholar
Lang, P. J., Bradley, M. M., & Cuthbert, B. N. (1995). International affective picture system (IAPS): Technical manual and affective ratings (Tech. Rep. A-4). Gainesville, FL: University of Florida, The Center for Research in Psychophysiology.
Lazarus, R. S. (1991). Cognition and motivation in emotion. American Psychologist 46, 352–367.CrossRefGoogle Scholar
Lazarus, R. S. (2003). Does the positive psychology movement have legs? Psychological Inquiry 14, 93–109.Google Scholar
Lenzenweger, M. F., Clarkin, J. F., Fertuck, E. A., & Kernberg, O. F. (2004). Executive neurocognitive functioning and neurobehavioral systems indicators in borderline personality disorder: A preliminary study. Journal of Personality Disorders 18, 421–438.CrossRefGoogle Scholar
Levesque, J., Eugene, F., Joanette, Y., Paquette, V., Mensour, B., Beaudoin, G., et al. (2003). Neural circuitry underlying voluntary suppression of sadness. Biological Psychiatry 53, 502–510.CrossRefGoogle Scholar
Levine, D., Marziali, E., & Hood, J. (1997). Emotion processing in borderline personality disorders. Journal of Nervous and Mental Disease 185, 240–246.CrossRefGoogle Scholar
Lieb, K., Rexhausen, J. E., Kahl, K. G., Schweiger, U., Philipsen, A., Hellhammer, D. H., et al. (2004). Increased diurnal salivary cortisol in women with borderline personality disorder. Journal of Psychiatric Research 38, 559–565.CrossRefGoogle Scholar
Lindauer, R. J., Booij, J., Habraken, J. B., Uylings, H. B., Olff, M., Carlier, I. V., et al. (2004). Cerebral blood flow changes during script-driven imagery in police officers with posttraumatic stress disorder. Biological Psychiatry 56, 853–861.CrossRefGoogle Scholar
Linehan, M. M. (1987). Dialectical behavior therapy: A cognitive behavioral approach to parasuicide. Journal of Personality Disorders 1, 328–333.CrossRefGoogle Scholar
Linehan, M. M. (1993). Cognitive–behavioral treatment of borderline personality disorder. New York: Guilford Press.
Links, P. S., Steiner, M., Offord, D. R., & Eppel, A. (1988). Characteristics of borderline personality disorder: A Canadian study. Canadian Journal of Psychiatry 33, 336–340.CrossRefGoogle Scholar
Logan, G. D., & Zbrodoff, N. J. (1979). When it helps to be mislead: Facilitative effects of increasing the frequency of conflicting stimuli in a Stroop-like task. Memory and Cognition 7, 166–174.CrossRefGoogle Scholar
Lyoo, I. K., Han, M. H., & Cho, D. Y. (1998). A brain MRI study in subjects with borderline personality disorder. Journal of Affective Disorders 50, 235–243.CrossRefGoogle Scholar
MacCoon, D. G., & Newman, J. P. (2005). Restricted gating in borderline personality disorder: Evidence from a picture–word Stroop. Unpublished manuscript.
MacCoon, D. G., Wallace, J. F., & Newman, J. P. (2004). Self-regulation: Context-appropriate balanced attention. In R. F. Baumeister & K. D. Vohs (Eds.), Handbook of self-regulation: Research, theory, and applications. New York: Guilford Press.
Mahler, M. S. (1972). On the first three subphases of the separation-individuation process. International Journal of Psycho-Analysis 53, 333–338.Google Scholar
Malatesta, C. Z. (1990). The role of emotions in the development and organization of personality. In R. A. Thompson (Ed.), Nebraska symposium on motivation, 1988: Socioemotional development (pp. 1–56). Lincoln, NE: University of Nebraska Press.
Malatesta–Magai, C. (1991). Development of emotion expression during infancy: General course and patterns of individual difference. In J. Garber & K. A. Dodge (Eds.), Development of emotion regulation and dysregulation (pp. 49–68). New York: Cambridge University Press.
Malinovsky–Rummell, R., & Hansen, D. J. (1993). Long-term consequences of physical abuse. Psychological Bulletin 114, 68–79.CrossRefGoogle Scholar
Matsuoka, Y., Yamawaki, S., Inagaki, M., Akechi, T., & Uchitomi, Y. (2003). A volumetric study of amygdala in cancer survivors with intrusive recollections. Biological Psychiatry 54, 736–743.CrossRefGoogle Scholar
Miller, E. K., & Cohen, J. D. (2001). An integrative theory of prefrontal cortex function. Annual Review of Neuroscience 24, 167–202.CrossRefGoogle Scholar
Miller, P., & Sperry, L. L. (1987). The socialization of anger and aggression. Merrill–Palmer Quarterly 33, 1–31.Google Scholar
Monarch, E. S., Saykin, A. J., & Flashman, L. A. (2004). Neuropsychological impairment in borderline personality disorder. Psychiatric Clinics of North America 27, 67–82.CrossRefGoogle Scholar
Morris, J. S., Friston, K. J., Buchel, C., Frith, C. D., Young, A. W., Calder, A. J., et al. (1998). A neuromodulatory role for the human amygdala in processing emotional facial expressions. Brain, 121(Pt. 1), 47–57.CrossRefGoogle Scholar
New, A. S., Buchsbaum, M. S., Hazlett, E. A., Goodman, M., Koenigsberg, H. W., Lo, J., et al. (2004). Fluoxetine increases relative metabolic rate in prefrontal cortex in impulsive aggression. Psychopharmacology (Berlin) 176, 451–458.CrossRefGoogle Scholar
New, A. S., Hazlett, E. A., Buchsbaum, M.., Goodman, M., Reynolds, D., Mitropoulou, V., et al. (2002). Blunted prefrontal cortical 18fluorodeoxyglucose positron emission tomography response to meta-chlorophenylpiperazine in impulsive aggression. Archives of General Psychiatry 59, 621–629.CrossRefGoogle Scholar
Newman, J. P., & Wallace, J. F. (1993). Diverse pathways to deficient self-regulation: Implications for disinhibitory psychopathology in children. Clinical Psychology Review 13, 699–720.CrossRefGoogle Scholar
Nigg, J. T., Lohr, N. E., Westen, D., Gold, L. J., & Silk, K. R. (1992). Malevolent object representations in borderline personality disorder and major depression. Journal of Abnormal Psychology 101, 61–67.CrossRefGoogle Scholar
Nigg, J. T., Silk, K. R., Stavro, G., & Miller, T. (2005). Disinhibition and borderline personality disorder. Development and Psychopathology 17, 1129–1149.CrossRefGoogle Scholar
Nigg, J. T., Silk, K. R., Westen, D., Lohr, N. E., Gold, L. J., Ogata, S. J., et al. (1991). Object representations in the early memories of sexually abused borderline subjects. American Journal of Psychiatry 148, 864–869.Google Scholar
Noy, S. (1982). Division-based psychiatry in intensive war situations: Suggestions for improvement. Journal of the Royal Army Medical Corps 128, 105–116.CrossRefGoogle Scholar
Ochsner, K. N., & Barrett, L. F. (2001). A multiprocess perspective on the science of emotion. In T. J. Mayne & G. A. Bonanno (Eds.), Emotions: Current issues and future directions (pp. 38–81). New York: Guilford Press.
Ochsner, K. N., Bunge, S. A., Gross, J. J., & Gabrieli, J. D. (2002). Rethinking feelings: An FMRI study of the cognitive regulation of emotion. Journal of Cognitive Neuroscience 14, 1215–1229.CrossRefGoogle Scholar
Ochsner, K. N., & Gross, J. J. (2004). Thinking makes it so: A social cognitive neuroscience approach to emotion regulation.. In R. F. Baumeister & K. D. Vohs (Eds.), Handbook of self-regulation: Research, theory, and applications. New York: Guilford Press.
Ochsner, K. N., Ray, R. D., Cooper, J. C., Robertson, E. R., Chopra, S., Gabrieli, J. D., et al. (2004). For better or for worse: Neural systems supporting the cognitive down- and up-regulation of negative emotion. NeuroImage 23, 483–499.CrossRefGoogle Scholar
Oquendo, M. A., & Mann, J. J. (2000). The biology of impulsivity and suicidality. Psychiatric Clinics of North America 23, 11–25.CrossRefGoogle Scholar
Pardo, J. V., Pardo, P. J., Janer, K. W., & Raichle, M. E. (1990). The anterior cingulate cortex mediates processing selection in the Stroop attentional conflict paradigm. Proceedings of the National Academy of Sciences of the United States of America 87, 256–259.CrossRefGoogle Scholar
Paris, J. (1999). Nature and nurture in psychiatry: A predisposition-stress model of mental disorders. Washington, DC: American Psychiatric Press.
Patterson, C. M., & Newman, J. P. (1993). Reflectivity and learning from aversive events: Toward a psychological mechanism for the syndromes of disinhibition. Psychological Review 100, 716–736.CrossRefGoogle Scholar
Pessoa, L., Kastner, S., & Ungerleider, L. G. (2002). Attentional control of the processing of neural and emotional stimuli. Cognitive Brain Research 15, 31–45.CrossRefGoogle Scholar
Posner, M. I., Rothbart, M. K., Vizueta, N., Levy, K. N., Evans, D. E., Thomas, K. M., et al. (2002). Attentional mechanisms of borderline personality disorder. Proceedings of the National Academy of Sciences of the United States of America 99, 16366–70163.CrossRefGoogle Scholar
Rolls, E. T. (1996). The orbitofrontal cortex. Philosophical Transactions of the Royal Society of London, Series B: Biological Sciences, 351, 1433–43; discussion 1443–1444.Google Scholar
Rothbart, M. K., & Bates, J. E. (1998). Temperament. In W. Damon & N. Eisenberg (Eds.), Handbook of child psychology: Vol. 3. Social, emotional, and personality development (5th ed., pp. 105–176). New York: Wiley.
Rothbart, M. K., Posner, M. I., & Boylan, A. (1990). Regulatory mechanisms in infant development. In J. T. Enns (Ed.), The development of attention: Research and theory (pp. 47–66). New York: Elsevier Science.
Rueda, M. R., Fan, J., McCandliss, B. D., Halparin, J. D., Gruber, D. B., Lercari, L. P., et al. (2004). Development of attentional networks in childhood. Neuropsychologia 42, 1029–1040.CrossRefGoogle Scholar
Rutter, M. (2002). The interplay of nature, nurture, and developmental influences: the challenge ahead for mental health. Archives of General Psychiatry 59, 996–1000.CrossRefGoogle Scholar
Sanislow, C. A., Grilo, C. M., Morey, L. C., Bender, D. S., Skodol, A. E., & Gunderson, J. G. (2002). Confirmatory factor analysis of DSM-IV borderline personality criteria: Findings from the Collaborative Longitudinal Personality Disorders Study. American Journal of Psychiatry 159, 276–283.Google Scholar
Schaefer, S. M., Jackson, D. C., Davidson, R. J., Aguirre, G. K., Kimberg, D. Y., & Thompson–Schill, S. L. (2002). Modulation of amygdala activity by the conscious regulation of negative emotion. Journal of Cognitive Neuroscience 14, 913–921.CrossRefGoogle Scholar
Schmahl, C. G., Elzinga, B. M., Vermetten, E., Sanislow, C., McGlashan, T. H., & Bremner, J. D. (2003). Neural correlates of memories of abandonment in women with and without borderline personality disorder. Biological Psychiatry 54, 142–151.CrossRefGoogle Scholar
Schmahl, C. G., McGlashan, T. H., & Bremner, J. D. (2002). Neurobiological correlates of borderline personality disorder. Psychopharmacological Bulletin 36, 69–87.Google Scholar
Schmideberg, M. (1947). The treatment of psychopaths and borderline patients. American Journal of Psychotherapy 1, 45–70.Google Scholar
Shearin, E. N., & Linehan, M. M. (1994). Dialectical behavior therapy for borderline personality disorder: theoretical and empirical foundations. Acta Psychiatrica Scandanavica Supplementum 379, 61–68.CrossRefGoogle Scholar
Sheline, Y. I., Wang, P. W., Gado, M. H., Csernansky, J. G., & Vannier, M. W. (1996). Hippocampal atrophy in recurrent major depression. Proceedings of the National Academy of Sciences of the United States of America 93, 3908–3913.CrossRefGoogle Scholar
Siever, L. J., Buchsbaum, M. S., New, A. S., Spiegel–Cohen, J., Wei, T., Hazlett, E. A., et al. (1999). d,l-Fenfluramine response in impulsive personality disorder assessed with. Neuropsychopharmacology 20, 413–423.CrossRefGoogle Scholar
Siever, L. J., & Davis, K. L. (1991). Psychobiological perspectives on the personality disorders. American Journal of Psychiatry 148, 1647–1658.Google Scholar
Siever, L. J., Torgersen, S., Gunderson, J. G., Livesley, W. J., & Kendler, K. S. (2002). The borderline diagnosis III: Identifying endophenotypes for genetic studies. Biological Psychiatry 51, 964–968.Google Scholar
Silk, K. R. (2000). Overview of biological factors in borderline personality disorder. Psychiatric Clinics of North America 23, 61–75.Google Scholar
Silk, K. R., Lee, S., Hill, E. M., & Lohr, N. E. (1995). Borderline personality disorder and severity of sexual abuse. American Journal of Psychiatry 152, 1059–1064.Google Scholar
Silk, K. R., Nigg, J. T., Westen, D., & Lohr, N. E. (1997). Severity of childhood sexual abuse, borderline symptoms, and familial environment. In M. Zanarini (Ed.), The role of sexual abuse in the etiology of borderline personality disorder (pp. 131–163). Washington, DC: American Psychiatric Press.
Soloff, P. H., Meltzer, C. C., Becker, C., Greer, P. J., Kelly, T. M., & Constantine, D. (2003). Impulsivity and prefrontal hypometabolism in borderline personality disorder. Psychiatry Research 123, 153–163.Google Scholar
Soloff, P. H., Meltzer, C. C., Greer, P. J., Constantine, D., & Kelly, T. M. (2000). A fenfluramine-activated FDG-PET study of borderline personality disorder. Biological Psychiatry 47, 540–547.Google Scholar
Spitzer, R. L., Endicott, J., & Gibbon, M. (1979). Crossing the border into borderline personality and borderline schizophrenia. The development of criteria. Archives of General Psychiatry 36, 17–24.Google Scholar
Stanley, M., & Mann, J. (1984). Suicide and serotonin receptors. Lancet 1, 349.Google Scholar
Stein, K. F. (1996). Affect instability in adults with a borderline personality disorder. Archives of Psychiatric Nursing 10, 32–40.Google Scholar
Stein, M. B., Koverola, C., Hanna, C., Torchia, M. G., & McClarty, B. (1997). Hippocampal volume in women victimized by childhood sexual abuse. Psychological Medicine 27, 951–959.Google Scholar
Stern, A. (1938). Psychoanalytic investigation and therapy in the borderline group of neuroses. Psychoanalytic Quarterly 7, 467–489.Google Scholar
Stiglmayr, C. E., Shapiro, D. A., Stieglitz, R. D., Limberger, M. F., & Bohus, M. (2001). Experience of aversive tension and dissociation in female patients with borderline personality disorder—A controlled study. Journal of Psychiatric Research 35, 111–118.Google Scholar
Sutton, S. K., Davidson, R. J., & Donzella, B. (1997). Manipulating affective state using extended picture presentations. Psychophysiology 34, 217–226.Google Scholar
Tebartz van Elst, L., Hesslinger, B., Thiel, T., Geiger, E., Haegele, K., Lemieux, L., et al. (2003). Frontolimbic brain abnormalities in patients with borderline personality disorder: A volumetric magnetic resonance imaging study. Biological Psychiatry 54, 163–171.Google Scholar
Thompson, R. A. (1987). Development of children's inferences of the emotions and others. Developmental Psychology 23, 124–131.Google Scholar
Thompson, R. A. (1994). Emotion regulation: A theme in search of definition. Monographs of the Society for Research in Child Development 59(2–3), 25–52.Google Scholar
Trull, T. J. (2001). Relationships of borderline features to parental mental illness, childhood abuse, Axis I disorder, and current functioning. Journal of Personality Disorders 15, 19–32.Google Scholar
Tzelgov, J., Henik, A., & Berger, J. (1992). Controlling Stroop effects by manipulating expectations for color words. Memory and Cognition 20, 727–735.Google Scholar
van Veen, V., Cohen, J. D., Botvinick, M. M., Stenger, V. A., & Carter, C. S. (2001). Anterior cingulate cortex, conflict monitoring, and levels of processing. NeuroImage 14, 1302–1308.Google Scholar
Vrana, S. R., Spence, E. L., & Lang, P. J. (1988). The startle probe response: A new measure of emotion. Journal of Abnormal Psychology 97, 487–491.Google Scholar
Vuilleumier, P., Armony, J. L., Driver, J., & Dolan, R. J. (2001). Effects of attention and emotion on face processing in the human brain: An event-related fMRI study. Neuron 30, 829–841.Google Scholar
Whalen, P. J., Bush, G., McNally, R. J., Wilhelm, S., McInerney, S. C., Jenike, M. A., et al. (1998). The emotional counting Stroop paradigm: A functional magnetic resonance imaging probe of the anterior cingulate affective division. Biological Psychiatry 44, 1219–1228.Google Scholar
Whalen, P. J., Kagan, J., Cook, R. G., Davis, F. C., Kim, H., Polis, S., et al. (2004). Human amygdala responsivity to masked fearful eye whites. Science, 306, 2061.Google Scholar
Whalen, P. J., Rauch, S. L., Etcoff, N. L., McInerney, S. C., Lee, M. B., & Jenike, M. A. (1998). Masked presentations of emotional facial expressions modulate amygdala activity without explicit knowledge. Journal of Neuroscience 18, 411–418.Google Scholar
Winnicott, D. W. (1960). The theory of the parent–infant relationship. International Journal of Psycho-Analysis 41, 585–595.Google Scholar
Yamasaki, H., LaBar, K. S., & McCarthy, G. (2002). Dissociable prefrontal brain systems for attention and emotion. Proceedings of the National Academy of Sciences of the United States of America 99, 11447–11451.Google Scholar
Yen, S., Shea, M. T., Battle, C. L., Johnson, D. M., Zlotnick, C., Dolan–Sewell, R., Skodol, A. E., et al. (2002). Traumatic exposure and posttraumatic stress disorder in borderline, schizotypal, avoidant, and obsessive–compulsive personality disorders: Findings from the collaborative longitudinal personality disorders study. Journal of Nervous and Mental Disease 190, 510–518.Google Scholar
Zanarini, M. C., & Frankenburg, F. R. (1994). Emotional hypochondrias, hyperbole, and the borderline patient. Journal of Psychotherapy and Research 3, 25–36.Google Scholar
Zanarini, M. C., Frankenburg, F. R., Hennen, J., & Silk, K. R. (2003). The longitudinal course of borderline psychopathology: A six-year prospective follow-up of the phenomenology of borderline personality disorder. American Journal of Psychiatry 160, 274–283.Google Scholar
Zanarini, M. C., Frankenburg, F. R., Reich, D. B., Marino, M. F., Lewis, R. E., Williams, A. A., et al. (2000). Biparental failure in the childhood experiences of borderline patients. Journal of Personality Disorders 14, 264–273.Google Scholar
Zanarini, M. C., Ruser, T. F., Frankenburg, F. R., Hennen, J., & Gunderson, J. G. (2000). Risk factors associated with the dissociative experiences of borderline patients. Journal of Nervous and Mental Disease 188, 26–30.Google Scholar
Zanarini, M. C., Williams, A. A., Lewis, R. E., Reich, R. B., Vera, S. C., Marino, M. F., et al. (1997). Reported pathological childhood experiences associated with the development of borderline personality disorder. American Journal of Psychiatry 154, 1101–1106.Google Scholar
Zanarini, M. C., Yong, L., Frankenburg, F. R., Hennen, J., Reich, D. B., Marino, M. F., et al. (2002). Severity of reported childhood sexual abuse and its relationship to severity of borderline psychopathology and psychosocial impairment among borderline patients. Journal of Nervous and Mental Disease 190, 381–387.Google Scholar
Zilboorg, G. (1941). Ambulatory schizophrenia. Psychiatry 4, 149–155.Google Scholar
Zubieta, J. K., Smith, Y. R., Bueller, J. A., Xu, Y., Kilbourn, M. R., Jewett, D. M., et al. (2002). Mu-opioid receptor-mediated antinociceptive responses differ in men and women. Journal of Neuroscience 22, 5100–5107.Google Scholar