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Restricted and repetitive behaviors in autism spectrum disorders: The relationship of attention and motor deficits

Published online by Cambridge University Press:  23 July 2013

Susan M. Ravizza ,
Marjorie Solomon ,
Richard B. Ivry  and
Cameron S. Carter
Susan M. Ravizza*
Affiliation:
Michigan State University
Marjorie Solomon
Affiliation:
University of California, Davis
Richard B. Ivry
Affiliation:
University of California, Berkeley
Cameron S. Carter
Affiliation:
University of California, Davis
*
Address correspondence and reprint requests to: Susan Ravizza, Department of Psychology, Michigan State University, East Lansing, MI 48824; E-mail: ravizzas@msu.edu.
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Abstract

Restricted and repetitive behaviors (RRBs) are hallmark symptoms of autism spectrum disorders (ASDs); however, it has proven difficult to understand the mechanisms underlying these behaviors. One hypothesis suggests that RRBs are the result of a core deficit in attention. Alternatively, abnormalities of the motor system may constitute the central mechanism underlying RRBs, given motor deficits observed in ASDs. In this experiment, we investigated the etiology of RRBs and the relationship between attention and motor deficits. Movement impairments (a) may be indirectly related to attention deficits, (b) may result from a shared compromised process, or (c) may be independent. Twenty-two adolescents with ASD and 20 typically developing participants performed a spatial attention task. Movement impairments were assessed with a rhythmic tapping task. Attentional orienting and motor control were found to be related and supported the hypothesis that these impairments in ASD arise from a shared process. In contrast, measures of attention switching and motor control were found to be independent. Stereotyped behaviors, as assessed by parental ratings, were related more to the degree of motor impairment than to deficits of attention. These results suggest that both attentional orienting deficits and stereotyped RRBs are related to a compromised motor system.

Type
Regular Articles
Information
Development and Psychopathology , Volume 25 , Issue 3 , August 2013 , pp. 773 - 784
Copyright
Copyright © Cambridge University Press 2013 

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References

Agam, Y., Joseph, R. M., Barton, J. J., & Manoach, D. S. (2010). Reduced cognitive control of response inhibition by the anterior cingulate cortex in autism spectrum disorders. NeuroImage, 52, 336–347.Google Scholar
Akshoomoff, N. (2000). Neurological underpinnings of autism. In Prizant, B., Wetherby, A., Dynlap, G., Mirenda, P., Rydell, P., & Williamson, G. (Eds.), Autism spectrum disorders: A transactional developmental perspective (pp. 167–190). Baltimore, MD: Paul H. Brookes.Google Scholar
Allen, G., & Courchesne, E. (2003). Differential effects of developmental cerebellar abnormality on cognitive and motor functions in the cerebellum: An fMRI study of autism. American Journal of Psychiatry, 160, 262–273.Google Scholar
Allman, M. J. (2011). Deficits in temporal processing associated with autistic disorder. Frontiers in Integrative Neuroscience, 5, 2.Google Scholar
Amaral, D. G., Schumann, C. M., & Nordahl, C. W. (2008). Neuroanatomy of autism. Trends in Neuroscience, 31, 137–145.CrossRefGoogle ScholarPubMed
American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: Author.Google Scholar
American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Washington DC: Author.Google Scholar
Barnes, K. A., Howard, J. H. Jr., Howard, D. V., Gilotty, L., Kenworthy, L., Gaillard, W. D., et al. (2008). Intact implicit learning of spatial context and temporal sequences in childhood autism spectrum disorder. Neuropsychology, 22, 563–570.Google Scholar
Behrmann, M., Thomas, C., & Humphreys, K. (2006). Seeing it differently: Visual processing in autism. Trends in Cognitive Science, 10, 258–264.Google Scholar
Bishop, S. L., Richler, J., & Lord, C. (2006). Association between restricted and repetitive behaviors and nonverbal IQ in children with autism spectrum disorders. Child Neuropsychology, 12, 247–267.Google Scholar
Bodfish, J. W., Symons, F. J., & Lewis, M. H. (1999). The Repetitive Behavior Scale. Western Carolina Center Research Reports. Cullowhee, NC: Western Carolina University.Google Scholar
Carcani-Rathwell, I., Rabe-Hasketh, S., & Santosh, P. J. (2006). Repetitive and stereotyped behaviours in pervasive developmental disorders. Journal of Child Psychology and Psychiatry, 47, 573–581.Google Scholar
Carter, C. S., Braver, T. S., Barch, D. M., Botvinick, M. M., Noll, D., & Cohen, J. D. (1998). Anterior cingulate cortex, error detection, and the online monitoring of performance. Science, 280, 747–749.CrossRefGoogle ScholarPubMed
Cohen, J. (1992). Statistical power analysis. Current Directions in Psychological Science, 1, 98–101.Google Scholar
Courchesne, E., & Allen, G. (1997). Prediction and preparation, fundamental functions of the cerebellum. Learning & Memory, 4, 1–35.CrossRefGoogle ScholarPubMed
Courchesne, E., Townsend, J., Akshoomoff, N. A., Saitoh, O., Yeung-Courchesne, R., Lincoln, A. J., et al. (1994). Impairment in shifting attention in autistic and cerebellar patients. Behavior Neuroscience, 108, 848–865.CrossRefGoogle ScholarPubMed
Denckla, M. B. (1985). Revised neurological examination for subtle signs. Psychopharmacology Bulletin, 21, 773–800.Google ScholarPubMed
Dowell, L. R., Mahone, E. M., & Mostofsky, S. H. (2009). Associations of postural knowledge and basic motor skill with dyspraxia in autism: Implication for abnormalities in distributed connectivity and motor learning. Neuropsychology, 23, 563–570.Google Scholar
Freitag, C. M., Kleser, C., Schneider, M., & von Gontard, A. (2007). Quantitative assessment of neuromotor function in adolescents with high functioning autism and Asperger syndrome. Journal of Autism and Developmental Disorders, 37, 948–959.Google Scholar
Ghajar, J., & Ivry, R. B. (2009). The predictive brain state: Asynchrony in disorders of attention? Neuroscientist, 15, 232–242.Google Scholar
Gidley Larson, J. C., & Mostofsky, S. H. (2008). Evidence that the pattern of visuomotor sequence learning is altered in children with autism. Autism Research, 1, 341–353.Google Scholar
Haas, R. H., Townsend, J., Courchesne, E., Lincoln, A. J., Schreibman, L., & Yeung-Courchesne, R. (1996). Neurologic abnormalities in infantile autism. Journal of Child Neurology, 11, 84–92.Google Scholar
Hallett, M., Lebiedowska, M. K., Thomas, S. L., Stanhope, S. J., Denckla, M. B., & Rumsey, J. (1993). Locomotion of autistic adults. Archives of Neurology, 50, 1304–1308.CrossRefGoogle ScholarPubMed
Harris, N. S., Courchesne, E., Townsend, J., Carper, R. A., & Lord, C. (1999). Neuroanatomic contributions to slowed orienting of attention in children with autism. Cognitive Brain Research, 8, 61–71.Google Scholar
Helmuth, L. L., Ivry, R. B., & Shimuzu, N. (1997). Preserved performance by cerebellar patients on tests of word generation, discrimination learning, and attention. Learning & Memory, 3, 456–474.CrossRefGoogle ScholarPubMed
Howlin, P. (2003). Outcome in high-functioning adults with autism with and without early language delays: Implications for the differentiation between autism and Asperger syndrome. Journal of Autism and Developmental Disorders, 33, 3–13.Google Scholar
Ivry, R. B., & Keele, S. W. (1989). Timing functions of the cerebellum. Journal of Cognitive Neuroscience, 1, 136–152.CrossRefGoogle ScholarPubMed
Kerns, J. G., Cohen, J. D., MacDonald, A. W. III, Cho, R. Y., Stenger, V. A., & Carter, C. S. (2004). Anterior cingulate conflict monitoring and adjustments in control. Science, 303, 1023–1026.CrossRefGoogle ScholarPubMed
Lam, K. S., & Aman, M. G. (2007). The Repetitive Behavior Scale—Revised: Independent validation in individuals with autism spectrum disorders. Journal of Autism and Developmental Disorders, 37, 855–866.Google Scholar
Landa, R., & Garrett-Mayer, E. (2006). Development in infants with autism spectrum disorders: A prospective study. Journal of Child Psychology and Psychiatry, 47, 629–638.Google Scholar
Langen, M., Durston, S., Kas, M. J. H., van Engeland, H., & Staal, W. G. (2011). The neurobiology of repetitive behavior: … and men. Neuroscience & Biobehavioral Reviews, 35, 356–365.Google Scholar
Lopez, B. R., Lincoln, A. J., Ozonoff, S., & Lai, Z. (2005). Examining the relationship between executive functions and restricted, repetitive symptoms of autistic disorder. Journal of Autism and Developmental Disorders, 35, 445–460.Google Scholar
Lord, C., Risi, S., Lambrecht, L., Cook, E. H. Jr., Leventhal, B. L., DiLavore, P. C., et al. (2000). The Autism Diagnostic Observation Schedule—Generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30, 205–223.CrossRefGoogle ScholarPubMed
Lord, C., Rutter, M., & Le Couteur, A. (1994). Autism Diagnostic Interview—Revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Journal of Autism and Developmental Disorders, 24, 659–685.CrossRefGoogle ScholarPubMed
Lundy-Ekman, L., Ivry, R., Keele, S., & Woollacott, M. (1991). Timing and force control in clumsy children. Journal of Cognitive Neuroscience, 3, 367–376.Google Scholar
Martin, L. A., Goldowitz, D., & Mittleman, G. (2010). Repetitive behavior and increased activity in mice with Purkinje cell loss: A model for understanding the role of cerebellar pathology in autism. European Journal of Neuroscience, 31, 544–555.CrossRefGoogle Scholar
Miller, E. K., & Cohen, J. D. (2001). An integrative theory of prefrontal cortex function. Annual Review of Neuroscience, 24, 167–202.Google Scholar
Ming, X., Brimacombe, M., & Wagner, G. C. (2007). Prevalence of motor impairment in autism spectrum disorders. Brain and Development, 29, 565–570.CrossRefGoogle ScholarPubMed
Minshew, N. J., Goldstein, G., & Siegel, D. J. (1997). Neuropsychologic functioning in autism: Profile of a complex information processing disorder. Journal of the International Neuropsychology Society, 3, 303–316.Google Scholar
Moruzzi, S., Ogliari, A., Ronald, A., Happe, F., & Battaglia, M. (2011). The nature of covariation between autistic traits and clumsiness: A twin study in a general population sample. Journal of Autism and Developmental Disorders, 41, 1665–1674.CrossRefGoogle Scholar
Mosconi, M. W., Kay, M., D'Cruz, A. M., Seidenfeld, A., Guter, S., Stanford, L. D., et al. (2009). Impaired inhibitory control is associated with higher-order repetitive behaviors in autism spectrum disorders. Psychological Medicine, 39, 1559–1566.CrossRefGoogle ScholarPubMed
Mostofsky, S. H., Burgess, M. P., & Gidley Larson, J. C. (2007). Increased motor cortex white matter volume predicts motor impairment in autism. Brain, 130, 2117–2122.Google Scholar
Mostofsky, S. H., Powell, S. K., Simmonds, D. J., Goldberg, M. C., Caffo, B., & Pekar, J. J. (2009). Decreased connectivity and cerebellar activity in autism during motor task performance. Brain, 132, 2413–2425.Google Scholar
Ozonoff, S., Cook, I., Coon, H., Dawson, G., Joseph, R. M., Klin, A., et al. (2004). Performance on Cambridge Neuropsychological Test Automated Battery subtests sensitive to frontal lobe function in people with autistic disorder: Evidence from the Collaborative Programs of Excellence in Autism Network. Journal of Autism and Developmental Disorders, 34, 139–150.CrossRefGoogle Scholar
Ozonoff, S., & Griffith, E. M. (2000). Neuropsychological function and the external validity of Asperger syndrome. In Klin, A., Volkmar, F. R., & Sparrow, S. S. (Eds.), Asperger syndrome (pp. 72–96). New York: Guilford Press.Google Scholar
Ozonoff, S., Young, G. S., Goldring, S., Greiss-Hess, L., Herrera, A. M., Steele, J., et al. (2008). Gross motor development, movement abnormalities, and early identification of autism. Journal of Autism and Developmental Disorders, 38, 644–656.Google Scholar
Pierce, K., & Courchesne, E. (2001). Evidence for a cerebellar role in reduced exploration and stereotyped behavior in autism. Biological Psychiatry, 49, 655–664.Google Scholar
Posner, M. I. (1980). Orienting of attention. Quarterly Journal of Experimental Psychology, 32, 3–25.Google Scholar
Ravizza, S. M., & Ivry, R. B. (2001). Comparison of the basal ganglia and cerebellum in shifting attention. Journal of Cognitive Neuroscience, 13, 285–297.CrossRefGoogle ScholarPubMed
Rogers, S. J., Bennetto, L., McEvoy, R., & Pennington, B. F. (1996). Imitation and pantomime in high-functioning adolescents with autism spectrum disorders. Child Development, 67, 2060–2073.Google Scholar
Shafritz, K. M., Dichter, G. S., Baranek, G. T., & Belger, A. (2008). The neural circuitry mediating shifts in behavioral response and cognitive set in autism. Biological Psychiatry, 63, 974–980.Google Scholar
Sheridan, J., & McAuley, J. D. (1997). Rhythm as a cognitive skill: Temporal processing deficits in autism. Paper presented at the 4th Australasian Cognitive Science Conference.Google Scholar
South, M., Ozonoff, S., & McMahon, W. M. (2005). Repetitive behavior profiles in Asperger syndrome and high-functioning autism. Journal of Autism and Developmental Disorders, 35, 145–158.CrossRefGoogle ScholarPubMed
Thakkar, K. N., Polli, F. E., Joseph, R. M., Tuch, D. S., Hadjikhani, N., Barton, J. J., et al. (2008). Response monitoring, repetitive behaviour and anterior cingulate abnormalities in autism spectrum disorders (ASD). Brain, 131, 2464–2478.Google Scholar
Townsend, J., Courchesne, E., Covington, J., Westerfield, M., Harris, N. S., Lyden, P., et al. (1999). Spatial attention deficits in patients with acquired or developmental cerebellar abnormality. Journal of Neuroscience, 19, 5632–5643.CrossRefGoogle ScholarPubMed
Townsend, J., Courchesne, E., & Egaas, B. (1996). Slowed orienting of covert visual–spatial attention in autism: Specific deficits associated with cerebellar and parietal abnormality. Development and Psychopathology, 8, 563–584.Google Scholar
Townsend, J., Westerfield, M., Leaver, E., Makeig, S., Jung, T., Pierce, K., et al. (2001). Event-related brain response abnormalities in autism: Evidence for impaired cerebello-frontal spatial attention networks. Cognitive Brain Research, 11, 127–145.Google Scholar
Travers, B. G., Klinger, M. R., Mussey, J. L., & Klinger, L. G. (2010). Motor-linked implicit learning in persons with autism spectrum disorders. Autism Research, 3, 68–77.CrossRefGoogle ScholarPubMed
Turner, M. A. (1999). Generating novel ideas: Fluency performance in high-functioning and learning disabled individuals with autism. Journal of Child Psychology and Psychiatry, 40, 189–201.Google Scholar
Wainwright-Sharp, J. A., & Bryson, S. E. (1993). Visual orienting deficits in high-functioning people with autism. Journal of Autism and Developmental Disorders, 23, 1–13.Google Scholar
Williams, H. G., Woollacott, M. H., & Ivry, R. (1992). Timing and motor control in clumsy children. Journal of Motor Behavior, 24, 165–172.CrossRefGoogle ScholarPubMed
Wing, A. M., & Kristofferson, A. B. (1973). Response delays and the timing of discrete motor responses. Perception & Psychophysics, 14, 5–12.Google Scholar
Yerys, B. E., Wallace, G. L., Harrison, B., Celano, M. J., Giedd, J. N., & Kenworthy, L. E. (2009). Set-shifting in children with autism spectrum disorders: Reversal shifting deficits on the Intradimensional/Extradimensional Shift Test correlate with repetitive behaviors. Autism, 13, 523–538.Google Scholar