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Prefrontal and Parietal Deficits in ADHD Suggested by Brain Electrical Activity Mapping During Children's Performance of the AX CPT

Published online by Cambridge University Press:  29 October 2015

Maree Farrow ,
Richard B. Silberstein ,
Florence Levy ,
Andrew Pipingas ,
Katie Wood ,
David A. Hay  and
Frederick C. Jarman
Maree Farrow*
Affiliation:
Brain Sciences Institute, Swinburne University of Technology, Melbourne
Richard B. Silberstein
Affiliation:
Brain Sciences Institute, Swinburne University of Technology, Melbourne
Florence Levy
Affiliation:
Avoca Clinic, Prince of Wales Children’s Hospital, Sydney
Andrew Pipingas
Affiliation:
Brain Sciences Institute, Swinburne University of Technology, Melbourne
Katie Wood
Affiliation:
School of Psychology, La Trobe University, Melbourne
David A. Hay
Affiliation:
School of Psychology, Curtin University, Perth
Frederick C. Jarman
Affiliation:
Centre for Community Child Health, Royal Children’s Hospital, Melbourne
*
Brain Sciences Institute, Swinbume University of Technology, PO Box 218, Hawthorn Victoria 3 122 Australia, Phone: (03) 92 14 52 15, Email: maf@mind.scan.swin.edu.au
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Abstract

Nine children meeting DSM-III-R criteria for Attention Deficit Hyperactivity Disorder (ADHD) and eighteen normal children participated in this study. A screening assessment revealed significantly more behavioural and academic problems in the ADHD group. Subjects performed a low demand visual vigilance task (the reference task) and the AX version of the continuous perfonnance task (CPT), while the steady-state visually evoked potential (SSVEP) was continuously recorded from 64 scalp electrode sites. The topography of the SSVEP amplitude difference between the reference and AX tasks was examined. In the 3.5 second interval between the appearances of the “A” and the “X” normal children showed transient reductions in right prefrontal SSVEP amplitude and a sustained reduction in right parieto-occipital SSVEP amplitude. These reductions in SSVEP amplitude were not seen in ADHD subjects. These results suggest that the presentation of a priming stimulus is associated with increased activation of right prefrontal and parieto-occipital regions in normal children, whereas the absence of this pattern of activation suggests a deficit in these processes in ADHD.

Keywords

ADHDContinuous Performance TaskRight PrefrontalParieto-occipital
Type
Research Article
Information
The Educational and Developmental Psychologist , Volume 13 , Issue 1: Special Double Issue: Attention Deficit Hyperactivity Disorder , May 1996 , pp. 59 - 68
Copyright
Copyright © Australian Psychological Society 1996

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References

REFERENCES

American Psychiatric Association (1994). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: Author.Google Scholar
American Psychiatrie Association (1987). Diagnostic and statistical manual of mental disorders (3rd ed., Rev.). Washington, DC: Author.Google Scholar
Barkley, R.A. (1995). Workshop manual: Attention deficit hyperactivity disorder in children and adolescents. University of Massachusetts Medical Centre, Worcester: Author.Google Scholar
Barkley, R.A. (1990). Attention deficit hyperactivity disorder: A handbook for diagnosis and treatment. New York: The Guilford Press.Google Scholar
Boder, E., & Jarrico, S. (1982). The Boder test of reading-spelling patterns. San Antonio: The Psychological Corporation.Google Scholar
Boucugnani, L.L., & Jones, R.W. (1989). Behaviours analogous to frontal lobe dysfunction in children with attention deficit hyperactivity disorder. Archives of Clinical Neuropsychology,4(2), 161–173.CrossRefGoogle Scholar
Chelune, G.J., Ferguson, W., Koon, R., & Dickey, T.O. (1986). Frontal lobe disinhibition in attention deficit disorder. Child Psychiatry and Human Development, 76(4), 221–234.CrossRefGoogle Scholar
Conners, C.K. (1973). Rating scales for use in drug studies with children. Psychopharmacology Bulletin (special issue), 9, 24–84.Google Scholar
Corkum, P.V., & Siegel, L.S. (1995). Debate and argument: Reply to Dr. Koelega: Is the continuous performance task a valuable research tool for use with children with attention deficit hyperactivity disorder? Comments on a review. Journal of Child Psychology and Psychiatry, 56(8), 1487–1493.CrossRefGoogle Scholar
Corkum, P.V., & Siegel, L.S. (1993). Is the continuous performance task a valuable research tool for use with children with attention deficit hyperactivity disorder? Journal of Child Psychology and Psychiatry, 34, 1217–1239.CrossRefGoogle ScholarPubMed
DuPaul, G.J. (1990). The ADHD rating scale: Normative data, reliability and validity. University of Massachusetts Medical Centre, Department of Psychiatry, Worcester: Author.Google Scholar
Edelbrock, C.S., & Achenbach, T.M. (1984). Child behaviour checklist – Teacher report form. Department of Psychiatry, University of Vermont, Burlington: Authors.Google Scholar
Emory University Division of Child and Adolescent Psychiatry. (1993). User’s manual for NIMH PC-DISC version 2.0. Atlanta: Author.Google Scholar
Holcomb, P.J., Ackerman, P.T., & Dykman, R.A. (1985). Cognitive event-related brain potentials in children with attention and reading deficits. Psychophysiology, 22(6), 656–667.CrossRefGoogle ScholarPubMed
Kaufman, A.S. (1979). Intelligent testing with the WISC-R. New York: John Wiley and Sons.Google Scholar
Klorman, R. (1991). Cognitive event-related potentials in attention deficit disorder. Journal of Learning Disabilities, 24(3), 130–140.CrossRefGoogle ScholarPubMed
Koelega, H.S. (1995). Is the continuous performance task a valuable research tool for use with children with attention deficit hyperactivity disorder? Comments on a review. Journal of Child Psychology and Psychiatry, 56(8), 1477–1485.CrossRefGoogle Scholar
Levy, F., & Hay, D.A. (1991). The Australian twin behaviour rating scale. Melbourne: La Trobe Twin Study, La Trobe University.Google Scholar
Levy, F., Hay, D.A., McLaughlin, M., Wood, K.E., & Waldman, I. (in press). Twin sibling differences in parental reports of ADHD, speech, reading and behaviour problems. Journal of Child Psychology and Psychiatry.Google Scholar
Lou, H.C., Henriksen, L., & Brunn, P. (1984). Focal cerebral hypoperfusion in children with dysphasia and/or attention deficit disorder. Archives of Neurology, 41, 825–829.CrossRefGoogle ScholarPubMed
Mazziota, J.C., & Phelps, M.E. (1984). Human sensory stimulation and deprivation: Positron emission tomographic results and strategies. Annals of Neurology (Suppl.), 75, 50–60.CrossRefGoogle Scholar
Michael, R.L., Klorman, R., Salzman, L.F., Borgstedt, A.D., & Dainer, K.B. (1981). Normalising effects of methylphenidate on hyperactive children’s vigilance performance and evoked potentials. Psychophysiology, 75(6), 665–677.CrossRefGoogle Scholar
Nunez, P.L., Silberstein, R.B., Cadusch, P.J., & Wijesinghe, R. (1993). Comparison of high resolution EEG methods having different theoretical bases. Brain Topography, 5, 361–364.CrossRefGoogle ScholarPubMed
Papanicolaou, A.C., & Johnstone, J. (1984). Probe evoked potentials: Theory, method and applications. International Journal of Neurosciences, 24, 107–131.CrossRefGoogle ScholarPubMed
Posner, M.I. (1988). Structures and functions of selective attention. In Boll, T. & Bryant, D.K. (Eds.), Clinical neuropsychology and brain function: Research, assessment and practice (pp. 173–202). Washington, DC: APA.CrossRefGoogle Scholar
Regan, D. (1989). Human brain electrophysiology: Evoked potentials and evoked magnetic fields in science and medicine. New York: Elsevier.Google Scholar
Roland, P.E. (1984). Metabolic measurements of the working frontal cortex in man. Trends in Neurosciences, 7, 430–435.CrossRefGoogle Scholar
Satterfield, J.H., Schell, A.M., & Nicholas, T. (1994). Preferential neural processing of attended stimuli in attention deficit hyperactivity disorder and normal boys. Psychophysiology, 31, 1–10.CrossRefGoogle ScholarPubMed
Sattler, J.M. (1992). Assessment of children (Rev. and updated 3rd ed.). California: Jerome M. Sattler Publisher Inc.Google Scholar
Shue, K.L., & Douglas, V.I. (1992). Attention deficit hyperactivity disorder and the frontal lobe syndrome. Brain and Cognition, 20, 104–124.CrossRefGoogle ScholarPubMed
Silberstein, R.B. (1995). Steady state visually evoked potentials, brain resonances and cognitive processes. In Nunez, P.L. (Ed.), Neocortical dynamics and human EEG rhythms (pp. 272–303). Oxford: Oxford University Press.Google Scholar
Silberstein, R.B., Cadusch, P.J., Nield, G., Pipingas, A., & Simpson, D.G. (in press). Steady state visually evoked potential topography dynamics and cognition. XIth international conference on event-related potentials of the brain. Exerpta Medica International Congress Series.Google Scholar
Silberstein, R.B., Ciorciari, J., & Pipingas, A. (1995). Steady state visually evoked potential topography during the Wisconsin card sorting test. Electroencephalography and Clinical Neurophysiology, 96, 24–35.CrossRefGoogle ScholarPubMed
Silberstein, R.B., Schier, M.A., Pipingas, A., Ciorciari, J., Wood, S.R., & Simpson, D.G. (1990). Steady-state visually evoked potential topography associated with a visual vigilance task. Brain Topography, 3(2), 337–347.CrossRefGoogle ScholarPubMed
Swanson, J.M., Shea, C., McBurnett, K., Potkin, S.G., Fiore, C., & Crinella, F. (1990). Attention and hyperactivity. In Enns, J.T. (Ed.), The development of attention: Research and theory (pp. 383–403). Amsterdam: Elsevier (North-Holland).CrossRefGoogle Scholar
Tucker, D.M., & Williamson, P.A. (1984). Asymmetric neural control systems in human self-regulation. Psychological Review, 91, 185–215.CrossRefGoogle ScholarPubMed
Whalen, C.K. (1989). Attention deficit and hyperactivity disorders. In Ollendick, T.H. & Hersen, M. (Eds.), Handbook of child psychopathology (2nd ed, pp. 131–169). New York: Plenum Press.CrossRefGoogle Scholar
Wechsler, D. (1992). Wechsler intelligence scale for children (3rd ed.). San Antonio: The Psychological Corporation.Google Scholar
Zametkin, A.J., Nordahl, T.E., Gross, M., King, A.C., Semple, W.E., Rumsey, J., Hamburger, S., & Cohen, R.M. (1990). Cerebral glucose metabolism in adults with hyperactivity of childhood onset. New England Journal of Medicine, 323, 1361–1366.CrossRefGoogle ScholarPubMed