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Age-specific incidence of neutralization antibodies of Herpes simplex virus

Published online by Cambridge University Press:  15 May 2009

Alexander L. Terzin  and
Milan G. Mašic`
Alexander L. Terzin
Affiliation:
Medical Faculty and Institute of Public Health, Novi Sad, Yugoslavia
Milan G. Mašic`
Affiliation:
Medical Faculty and Institute of Public Health, Novi Sad, Yugoslavia
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Summary

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Sera of 1255 individuals from Novi Sad, varying in age from <1 month to 69 years, have been tested for neutralization antibodies to Herpes simplex virus type 1.

The eight newborns tested and 97% of the 507 adults were positive, with titres ranging from 1/4 to 1/256. The titres in newborns were significantly lower than the titres in adults.

After birth the maternal antibodies declined rapidly and 94% of infants at the age of >6 months and <2 years were negative.

After the first year infants in Novi Sad start to acquire herpes-neutralizing antibodies actively, reaching a 50% incidence of positives between the 2nd and 3rd year of age.

Age-specific incidence rates of herpes positives found in Novi Sad have been compared with those reported from Edinburgh, Freiburg i. Br. and Louisiana. Possible influences of several circumstances upon the incidence rate of positives detected by the neutralization test are discussed.

Type
Research Article
Information
Journal of Hygiene , Volume 77 , Issue 2 , October 1976 , pp. 155 - 160
Copyright
Copyright © Cambridge University Press 1976

References

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