Hostname: page-component-cd9895bd7-hc48f Total loading time: 0 Render date: 2024-12-28T05:56:25.640Z Has data issue: false hasContentIssue false
  • English
  • Français

An Experimental Investigation on the Influence of Emulsions of Oils and Fats on the Lethal Effects of Bacterial Toxins

Published online by Cambridge University Press:  15 May 2009

G. Norman Myers
G. Norman Myers
Affiliation:
From the Pharmacological Laboratory, Cambridge
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

It is now generally accepted that certain bacterial toxins are able to give rise to fatty degeneration in tissues and may bring about marked changes of this nature in the heart, liver, kidneys and other organs. When a cell is damaged a state of cloudy swelling or of parenchymatous degeneration generally occurs. The fat is distributed throughout the cell as fine globules and the condition is known as fatty degeneration. Numerous workers (see References) are agreed that many toxins, particularly diphtheria toxin, may cause a widespread damage to cells of the body in this way. The processes involved in the deposition of this fat have led to much discussion and speculation, but do not concern us here.

Type
Research Article
Information
Journal of Hygiene , Volume 34 , Issue 2 , June 1934 , pp. 250 - 264
Copyright
Copyright © Cambridge University Press 1934

References

REFERENCES

Abramow, S. (1912). Ztschr. f. Immunitätsforsch. u. exp. Therap. 15, 12.Google Scholar
Avigagnet, E. C., Lutenbacher, R. and Le, Soudier (1918). Arch. de Malad. du Coeur, 2, 241.Google Scholar
Coghlan, E. F. (1912). Brit. Med. J. 1, 534.CrossRefGoogle Scholar
Councilman, W. T., Mallory, F. B. and Pearce, R. M. (1901). J. Boston Med. Soc. 1, 137.Google Scholar
Farr, C. B. (1920). Pernn. Med. J. 23, 633.Google Scholar
Fleming, G. B. and Kennedy, A. M. (1910). Heart, 2, 77.Google Scholar
Gunn, J. A. (1920). J. Physiol. 54, 89P.Google Scholar
Hecht, A. F. (1913). Ergeb. d. inn. Med. u. Kinderh. 2, 324, 413.Google Scholar
Holt, L. E. (1920). Diseases of Infancy and Childhood. New York: Appleton and Co. pp. 835, 1038.Google Scholar
Hume, W. E. and Clegg, S. J. (1914). Quart. J. Med. 8, 1.CrossRefGoogle Scholar
Loth, M. (1923). Arch. Int. Med. 31, 637.CrossRefGoogle Scholar
Myers, G. N. (1932). J. Pharm. Exp. Therap. 44, 191.Google Scholar
Myers, G. N. (1932). Further Experimental Investigations on the Action of Digitalis and some other Drugs in Toxaemia. Thesis for the Ph.D. Degree Cantab.Google Scholar
Myers, G. N. (1932). Abstracts of Dissertations for the Ph.D. Degree in the Univ. of Cambridge. Camb. Univ. Press.Google Scholar
Myers, G. N. (1933). J. Pharm. Exp. Therap. 49, 483.Google Scholar
Myers, G. N. (1934). Brit. Med. J. 1, 504.CrossRefGoogle Scholar
Walsh, V. G. and Frazer, A. C. (1934). Brit. Med. J. 1, 557.CrossRefGoogle Scholar