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The carcinogenic activity of some petroleum fractions and extracts. Comparative results in tests on mice repeated after an interval of eighteen months

Published online by Cambridge University Press:  15 May 2009

D. L. Woodhouse  and
J. O. Irwin
D. L. Woodhouse
Affiliation:
From the Cancer Research Laboratory, The Medical School, The University of Birmingham
J. O. Irwin
Affiliation:
From the Medical Research Council's Statistical Research Unit, London School of Hygiene and Tropical Medicine, The University of London
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Woodhouse's experiments on the carcinogenicity of ten different fractions for the skin of mice have been analysed statistically. Two experiments separated by a considerable period of time were performed on each fraction.

A number of different measures of carcinogenicity were used. All agree in showing that

(1) The apparent carcinogenicity was greater in the 2nd series of experiments.

(2) There were significant differences in carcinogenicity. The fractions can be divided into three groups within which the carcinogenicities were about the same, viz. F H I K, B D G L E, M.

Type
Research Article
Information
Journal of Hygiene , Volume 48 , Issue 1 , March 1950 , pp. 121 - 134
Copyright
Copyright © Cambridge University Press 1950

References

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