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Clearance of antibiotics from the intestines after termination of antibiotic decontamination

Published online by Cambridge University Press:  15 May 2009

D. van der Waaij
Affiliation:
Radiobiological Institute TNO, 151 Lange Kleiweg, Rijswijk (Z.H.), The Netherlands
J. E. C. Lekkerkerk-van der Wees
Affiliation:
Radiobiological Institute TNO, 151 Lange Kleiweg, Rijswijk (Z.H.), The Netherlands
P. J. Heidt
Affiliation:
Radiobiological Institute TNO, 151 Lange Kleiweg, Rijswijk (Z.H.), The Netherlands
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Summary

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The clearance of neomycin and kanamycin from the intestines after stopping oral supply has been determined in mice. Both antibiotics, although given in different doses, were excreted in essentially the same way; the clearance being a little faster than logarithmically in both cases. The importance of this observation with regard to isolation and the moment of reconventionalization is discussed.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1974

References

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