Hostname: page-component-78c5997874-4rdpn Total loading time: 0 Render date: 2024-11-14T04:26:21.788Z Has data issue: false hasContentIssue false

Complement-fixation by the Interaction of Normal Serum and Bacterial Suspensions—a Contribution to the Study of Natural Immunity Phenomena

Published online by Cambridge University Press:  15 May 2009

T. J. Mackie
Affiliation:
(Bacteriology Department, Edinburgh University.)
M. H. Finkelstein
Affiliation:
(Bacteriology Department, Edinburgh University.)
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

In a previous communication the authors drew attention to the occurrence of complement-fixation by normal serum along with various non-antigenic substances, and recorded the results of a study of this phenomenon with particular reference to the serum principle or principles concerned in the reaction (Mackie and Finkelstein, 1928). Though no conclusive interpretation of the results could be offered, a close analogy was established between the reacting agent of the serum and a natural antibody, e.g. a natural haemolysin, and the observations appeared to be of significance in relation to natural immunity phenomena.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1930

References

REFERENCES

Arkwright, J. A. (1927). J. Pathol. and Bacteriol. 30, 345.CrossRefGoogle Scholar
Bordet, J. (1899). Ann. Inst. Pasteur, 13, 225.Google Scholar
Braun, H. (1909). Archiv f. Hygiene, 68, 116.Google Scholar
Browning, C. H. (1927). Brit. Med. J. 2, 978.CrossRefGoogle Scholar
Dunlop, E. M. (1928). J. Pathol. and Bacteriol. 31, 769.CrossRefGoogle Scholar
Ehrlich, P. (1900). Proc. Boy. Soc. B, 66, 424.Google Scholar
Gengou, O. (1899). Ann. Inst. Pasteur, 13, 642.Google Scholar
Goldberg, S. J. (1901). Centralbl.f. Bakteriol. Abt. I, Orig. 30, 605.Google Scholar
Kolmer, J. A. and Trist, M. E. (1916). J. Infect. Diseases, 18, 20.CrossRefGoogle Scholar
Kolmer, J. A., Trist, M. E. and Heist, G. D. (1916). J. Infect. Diseases, 18, 27.CrossRefGoogle Scholar
Kratts, R. and Low, L. (1899). Wien. Klin. Wochenschr. 12, 95.Google Scholar
Landsteiner, K. and Reich, M. (1908). Zeitschr. f. Hygiene, 58, 213.CrossRefGoogle Scholar
Lüdke, H. (1904). Centralbl. f. Bakteriol. Abt. I, Orig. 37, 418.Google Scholar
Mackie, T. J. and Finkelstein, M. H. (1928). J. Hygiene, 28, 172.CrossRefGoogle Scholar
Mackie, T. J. and Watson, H. F. (1926). J. Hygiene, 25, 176.CrossRefGoogle Scholar
Rissling, P. (1907). Centralbl. f. Bakteriol. Abt. I, Orig. 44, 363.Google Scholar
Takenomata, N. (1924). Zeitschr. f. Immunitäts. 41, 508.Google Scholar
Thiele, F. H. and Embleton, D. (1914). Zeitschr. f. Immunitäts. 20, 1.Google Scholar