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The Distribution of Antibody to Crystalline Egg Albumin in the Serum of Injected Rabbits

Published online by Cambridge University Press:  15 May 2009

Muriel E. Adair  and
G. L. Taylor
Muriel E. Adair
Affiliation:
From the Department of Pathology, University of Cambridge
G. L. Taylor
Affiliation:
From the Department of Pathology, University of Cambridge
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Two batches of pooled antisera obtained from rabbits injected with crystalline egg albumin have been fractionated with ammonium sulphate in order to investigate the distribution of the antibody to this antigen in the serum proteins.

The albumin fractions contained no antibody.

All the globulin fractions examined contained antibody, and flocculated readily when mixed with appropriate dilutions of the antigen.

The distribution of antibody throughout the serum globulin was fairly uniform, the ratio of the antibody content to the protein concentration being the smallest in a fraction with a solubility in ammonium sulphate slightly lower than that of pseudoglobulin.

Type
Research Article
Information
Journal of Hygiene , Volume 36 , Issue 4 , October 1936 , pp. 564 - 569
Copyright
Copyright © Cambridge University Press 1936

References

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