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The effect of tuberculin on sensitized and normal leucocytes

Published online by Cambridge University Press:  15 May 2009

J. Marks
Affiliation:
Central Tuberculosis Laboratory, Cardiff
Dinah M. James
Affiliation:
Department of Pharmacology, Welsh National School of Medicine
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It has been shown that the cells in exudates produced by the injection of tuberculin into the serous cavities of sensitized animals are alive and not dead as claimed previously. Such cells consumed oxygen and glucose at the same rate as cells obtained similarly from normal animals but moved somewhat less actively. Purified tuberculin had no specific effect on the respiration in vitro of macrophages or neutrophil leucocytes derived from sensitized animals.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1953

References

Baldridge, G. D. & Kligman, A. M. (1951). Amer. Rev. Tuberc. 63, 674.Google Scholar
Cruickshank, C. N. D. (1951). Nature, Lond., 168, 206.CrossRefGoogle Scholar
Holst, P. M. (1922). Tubercle, Lond., 3, 337.CrossRefGoogle Scholar
Keller, W. (1927). Klin. Wschr. 6, 2460.CrossRefGoogle Scholar
Martin, S. P., Pierce, Cynthia H., Middlebrook, G. & Dubos, R. J. (1950). J. exp. Med. 91, 381.CrossRefGoogle Scholar
Rich, A. R. & Lewis, M. R. (1932). Johns Hopk. Hosp. Bull. 50, 115.Google Scholar
Stewart, F. W., Long, P. H. & Bradley, J. I. (1926). Amer. J. Path. 2, 47.Google Scholar