Hostname: page-component-cd9895bd7-7cvxr Total loading time: 0 Render date: 2024-12-26T22:22:03.523Z Has data issue: false hasContentIssue false
  • English
  • Français

Etiological factors in broncho-pneumonia amongst infants in London

Published online by Cambridge University Press:  15 May 2009

G. Payling Wright  and
Helen Payling Wright
G. Payling Wright
Affiliation:
From the Department of Pathology, Guy's Hospital Medical School
Helen Payling Wright
Affiliation:
From the Department of Pathology, Guy's Hospital Medical School
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

1. In the period 1923–39, more than one-fifth of all deaths in the age group 0-2 years in the Administrative County of London are recorded as having been caused by bronchitis or broncho-pneumonia. It is very unlikely that the returns have been exaggerated by more than 10–15% through the inclusion of deaths from secondary broncho-pneumonia following measles, whooping cough or influenza. In the 8 years in which measles epidemics occurred, the peak of the measles mortality was from 2 to 17 weeks after, and never before, that of the mortality from broncho-pneumonia.

2. The winter rise in mortality from broncho-pneumonia is not associated with any comparable increase in the carrier rates for pneumococci and haemolytic streptococci.

3. The broncho-pneumonia mortality of infants in the Metropolitan Boroughs is strongly correlated with sub-standard housing incidence, social index and percentage below the poverty line. The relatively small value found for the coefficient of regression between broncho-pneumonia mortality and sub-standard housing may be due to the less rigorous winter temperatures occurring in the more overcrowded central areas.

4. Low external temperature appears to be the most important predisposing cause of fatal broncho-pneumonia in infants; their weekly death-rate from this disease in mid-winter is about seven times that in the late summer. This great seasonal fluctuation in mortality is also found for persons over 55 years in the Administrative County, and for persons of all ages in both the urban and rural districts of the Home Counties.

5. The weekly mortalities of infants from broncho-pneumonia in the Administrative County are most strongly correlated with low temperatures 2 weeks earlier. The two variables are so associated that the mortality rises sharply when the mean temperature of the coldest day of the week falls below 40° F. There is no indication that low temperatures in the spring are associated with higher death-rates from broncho-pneumonia than the same temperatures in the autumn, so that the data provide no support for the supposition that susceptibility increases during the winter in consequence of the progressive depletion in the body of protective nutrient substances.

6. Possible measures to reduce the mortality of infants from broncho-pneumonia are discussed.

Type
Research Article
Information
Journal of Hygiene , Volume 44 , Issue 1 , January 1945 , pp. 15 - 30
Copyright
Copyright © Cambridge University Press 1945

References

REFERENCES

Brownlee, J. (1924-1925). J. Hyg., Camb., 23, 437.Google Scholar
Bullowa, J. G. M. & Greenbaum, E. (1937). Amer. J. Dis. Child. 53, 22.Google Scholar
Butler, C. D., Shaw, N. G., Hoffman, S. J., Ditkowski, S. & McVey, E. (1941). J. Amer. Med. Ass. 117, 1840.CrossRefGoogle Scholar
Cralley, L. J. (1942). Amer. J. Hyg. 36, 303.Google Scholar
Cruickshank, B. (1942). Control of the Common Fevers. London.Google Scholar
Dunlop, J. C. (1916). J. Roy. Stat. Soc. 79, 309.CrossRefGoogle Scholar
Farr, W. (1885a). Vital Statistics. London, p. 206.Google Scholar
Farr, W. (1885b). Vital Statistics. London, p. 175.Google Scholar
Farr, W. (1885c). Vital Statistics. London, p. 219.Google Scholar
Fisher, R. A. (1941). Statistical Methods for Research Workers, 8th ed. London.Google Scholar
Greenwood, M. (1920). Min. of Hlth Rep. on Publ. Hlth Med. Subjects, Lond., No. 4.Google Scholar
Greenwood, M. (1928). See Wood, H. M.Google Scholar
Gundel, M. & Schwarz, F. K. T. (1931). Z. Hyg. u. InfektKr. 113, 411.CrossRefGoogle Scholar
Hart, P. D'A. & Wright, G. Payling (1939). Tuberculosis and Social Conditions. London.Google Scholar
Heberden, W., Jr. (1796). Philos. Trans. Pt 2, 279.Google Scholar
Hendry, E. (1942). Arch. Dis. Child. 17, 111.CrossRefGoogle Scholar
Hooker, R. H. (1905). J. Roy. Stat. Soc. 68, 696.CrossRefGoogle Scholar
Hooker, R. H. (1907). J. Roy. Stat. Soc. 70, 1.CrossRefGoogle Scholar
Huntington, E. (1924). Civilization and Climate, 3rd ed. New Haven, Conn.Google Scholar
Kaufmann, E. (1929). Pathology. vol. 1, London.Google Scholar
Kneeland, Y. Jr (1930). J. Exp. Med. 51, 617.CrossRefGoogle Scholar
Lieber, K. (1931). Zbl. Bakt. 122, 476.Google Scholar
Long, A. P., McKhann, C. F. & Cheney, L. L. (1939). Amer. J. Dis. Child. 57, 1363.CrossRefGoogle Scholar
Madsen, T. (1930). Publ. Hlth, Lond., 43, 309.Google Scholar
Mudd, S., Goldman, A. & Grant, S. B. (1921). J. Exp. Med. 34, 11.CrossRefGoogle Scholar
Nedzel, A. J. (1935). Illinois Med. J. 68, 340.Google Scholar
Nemir, R. L., Andrews, E. T. & Vinograd, J. (1936). Amer. J. Dis. Child. 51, 1277.CrossRefGoogle Scholar
Neufeld, F. & Etinger-Tulczynska, R. (1932). Contrib. to Med. Sci. in honour of E. Libman, vol. 2. New York.Google Scholar
New Survey of London Life and Labour (1930), 3, 6. London.Google Scholar
Nungester, W. J. & Klepser, R. G. (1938). J. Infect. Dis. 63, 94.CrossRefGoogle Scholar
Powell, J. P., Atwater, R. N. & Felton, L. D. (1926). Amer. J. Hyg. 6, 570.Google Scholar
Rosher, A. B. (1939). Min. of Hlth Rep. on Publ. Hlth Med. Subjects, Lond., No. 90.Google Scholar
Russell, W. T. (1924). Lancet, 207, 335.CrossRefGoogle Scholar
Russell, W. T. (1926). Lancet, 209, 1128.CrossRefGoogle Scholar
Smith, C. M. (1928). J. Hyg., Camb., 27, 328.CrossRefGoogle Scholar
Straker, E., Hill, A. B. & Lovell, R. (1939). Min. of Hlth Rep. on Publ. Hlth Med. Subjects, Lond., No. 90.Google Scholar
Trask, J. D. (1942). Brennemann's Practice of Pediatrics. vol. 2. Hagerstown, Md.Google Scholar
Wells, W. F. & Stone, W. R. (1934). Amer. J. Hyg. 20, 619.Google Scholar
Wilson, G. S. (1930). J. Hyg., Camb., 30, 196.CrossRefGoogle Scholar
Woods, H. M. (1927). J. Hyg., Camb., 26, 36.CrossRefGoogle Scholar
Woods, H. M. (1928). Lancet, 214, 559.Google Scholar
Worringer, P. (1928). J. Méd. de Lyon, 9, 707.Google Scholar
Wright, G. Payling & Wright, H. Payling (1942). J. Hyg., Camb., 42, 451.Google Scholar
Young, M. (1924). J. Hyg., Camb., 23, 151.CrossRefGoogle Scholar
Yule, G. U. & Kendall, M. G. (1940). An Introduction to the Theory of Statistics. London.Google Scholar