Hostname: page-component-78c5997874-g7gxr Total loading time: 0 Render date: 2024-11-15T01:57:40.796Z Has data issue: false hasContentIssue false
  • English
  • Français

The excretion of two virulent strains of African swine fever virus by domestic pigs

Published online by Cambridge University Press:  15 May 2009

A. Greig  and
W. Plowright
A. Greig
Affiliation:
East African Veterinary Research Organization, Muguga, P.O. Kabete, Kenya
W. Plowright
Affiliation:
East African Veterinary Research Organization, Muguga, P.O. Kabete, Kenya
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Daily observations were made on the excretion of African swine fever (ASF) virus by pigs infected intranasally or by contact. Two strains of virus having mean death times of approximately 3 and 6 days were used, the latter being recently isolated from a warthog.

First excretion usually occurred by the nasopharyngeal route, as early as 1 or 2 days before the onset of fever in many cases. The titres of pharyngeal and nasal swabs rose rapidly to reach mean levels of about 104–106 HAD 50 at 48–72 hr. following the onset of pyrexia. Virus in the secretions of the conjunctiva or lower urogenital tract appeared later and did not attain such high levels. Faecal and urinary excretion was of relatively little significance, except in slower infections caused by the recent warthog virus.

These results are discussed in relation to the known failure of infected pigs to transmit the disease to stallmates during the first 12–24 hr. of pyrexia and also in relation to recent work on the pathogenesis of ASF in domestic swine.

Type
Research Article
Information
Journal of Hygiene , Volume 68 , Issue 4 , December 1970 , pp. 673 - 682
Copyright
Copyright © Cambridge University Press 1970

References

REFERENCES

Colgrove, G. S., Haeltermast, E. O. & Coggins, L. (1969). Pathogenesis of African swine fever in young pigs. American Journal of Veterinary Research 30, 1343–59.Google Scholar
Cox, B. F. & Hess, W. R. (1962). Note on an African swine fever investigation in Nyasaland. Bulletin of Epizootic Diseases of Africa 10, 439–40.Google Scholar
DeTray, D. E. (1963). African swine fever. Advances in Veterinary Science 8, 299–333.Google Scholar
Dougherty, R. M. (1964). In Techniques in Experimental Virology, Ed. Harris, R. C. J.. Academic Press.Google Scholar
Dulbecco, R. & Vogt, M. (1954). Plaque formation and isolation of pure lines of poliomyelitis viruses. Journal of Experimental Medicine 99, 167–82.Google Scholar
Heuschele, W. P. (1967). Studies on the pathogenesis of African swine fever. Archiv für die gesamte Virusforschung 21, 349–56.Google Scholar
Malmquist, W. A. & Hay, D. (1960). Hemadsorption and cytopathic effect produced by African swine fever virus in swine bone marrow and buffy coat cultures. American Journal of Veterinary Research 21, 104–8.Google Scholar
Montgomery, R. E. (1921). On a form of swine fever occurring in British East Africa (Kenya Colony). Journal of Comparative Pathology and Therapeutics 34, 159–91.Google Scholar
Plowright, W., Parker, J. & Peirce, M. A. (1969). The epizootiology of African swine fever in Africa. Veterinary Record 85, 668–74.Google Scholar
Plowright, W., Parker, J. & Staple, R. F. (1968). The growth of a virulent strain of African swine fever virus in domestic pigs. Journal of Hygiene 66, 117–34.Google Scholar
Plowright, W. & Staple, R. F. (1967). East African Veterinary Research Organization Anual Report, 1967, p. 12. East African Community, Arusha, Tanzania.Google Scholar
Scott, G. R. (1965). African swine fever virus. Veterinary Record 77, 1421–7.Google Scholar