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Experimental model of oral antityphoid vaccination with live streptomycin-dependent Salmonella typhimurium in C57BL/6 mice

Published online by Cambridge University Press:  15 May 2009

I. R. Vladoianu  and
F. Dubini
I. R. Vladoianu
Affiliation:
Institute of Pharmacology, University of Milan, Medical School, Milan, Italy
F. Dubini
Affiliation:
Institute of Pharmacology, University of Milan, Medical School, Milan, Italy
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Summary

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The present experimental model offered the opportunity to study particular aspects concerning the avirulence stability of live streptomycin-dependent (Sm D) Salmonella vaccines, under conditions resembling human enteric fever. The results seem to indicate that, in practice, the risk of reversion to a virulent form during oral antityphoid vaccination with Sm D strains remains slight even after the interruption of concomitant streptomycin administration.

Type
Research Article
Information
Journal of Hygiene , Volume 75 , Issue 2 , October 1975 , pp. 215 - 218
Copyright
Copyright © Cambridge University Press 1975

References

REFERENCES

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