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Exploring the time to intervene with a reactive mass vaccination campaign in measles epidemics

Published online by Cambridge University Press:  26 January 2006

R. F. GRAIS ,
X. DE RADIGUÈS ,
C. DUBRAY ,
F. FERMON  and
P. J. GUERIN
R. F. GRAIS
Affiliation:
Epicentre, 8 rue Saint Sabin, Paris, France
X. DE RADIGUÈS
Affiliation:
Epicentre, 8 rue Saint Sabin, Paris, France
C. DUBRAY
Affiliation:
Epicentre, 8 rue Saint Sabin, Paris, France
F. FERMON
Affiliation:
Médecins sans Frontières, 8 rue Saint Sabin, Paris, France
P. J. GUERIN
Affiliation:
Epicentre, 8 rue Saint Sabin, Paris, France
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Abstract

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The current WHO policy during measles outbreaks focuses on case management rather than reactive vaccination campaigns in urban areas of resource-poor countries having low vaccine coverage. Vaccination campaigns may be costly, or not timely enough to impact significantly on morbidity and mortality. We explored the time available for intervention during two recent epidemics. Our analysis suggests that the spread of measles in African urban settings may not be as fast as expected. Examining measles epidemic spread in Kinshasa (DRC), and Niamey (Niger) reveals a progression of smaller epidemics. Intervening with a mass campaign or in areas where cases have not yet been reported could slow the epidemic spread. The results of this preliminary analysis illustrate the importance of revisiting outbreak response plans.

Type
Research Article
Information
Epidemiology & Infection , Volume 134 , Issue 4 , August 2006 , pp. 845 - 849
Copyright
2006 Cambridge University Press