A high proportion of young men in this country suffer from premature baldness. Alopecia is not a disease entity but one of the outstanding features of chronic fluorine poisoning (fluorosis). It is frequently associated with dystrophies of other organs of ectodermal origin, namely, those of the skin and its other appendages, the teeth and nails. Since all these organs are regulated by the parathyroid glands, it is concluded that alopecia, too, is produced by fluorine acting through the medium of these endocrine glands. By its ability to precipitate the calcium content of the body, fluorine may lay the foundation for alopecia already in intra-uterine life, or produce it at any time after birth.
The action of fluorine is closely similar to that of thallium. There is ample evidence to show that in both fluorosis and chronic thallium poisoning the vegetative nervous system is vitally involved.
Toxic alopecia due. to fluorine is preventable.