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Further studies on the antibiotic resistance of Shigella sonnei: II. The acquisition of transferable antibiotic resistance in vivo

Published online by Cambridge University Press:  15 May 2009

Joan R. Davies ,
W. N. Farrant  and
A. J. H. Tomlinson
Joan R. Davies
Affiliation:
Public Health Laboratory, County Hall, London, S.E. 1
W. N. Farrant
Affiliation:
Public Health Laboratory, County Hall, London, S.E. 1
A. J. H. Tomlinson
Affiliation:
Public Health Laboratory, County Hall, London, S.E. 1
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A method is described for the testing of strains of Sh. sonnei for antibiotic resistance, colicine type and drug resistance transfer using a multiple inoculator.

The examination of 731 strains of Sh. sonnei isolated from convalescent cases and their family contacts showed that about 5% of individuals were excreting organisms which differed from the infecting strain by a single transferable antibiotic resistance determinant. It is suggested that the acquisition of such resistance may occur in 13% of family incidents.

Type
Original Articles
Information
Journal of Hygiene , Volume 66 , Issue 3 , September 1968 , pp. 479 - 487
Copyright
Copyright © Cambridge University Press 1968

References

Abbott, J. D. & Shannon, R. (1958). A method of typing Shigella sonnei using colicine production as a marker. J. clin. Path. 11, 71.CrossRefGoogle ScholarPubMed
Davies, Joan R. (1954). A simple method of determining the sulphonamide sensitivity of Shigella sonnei. Mon. Bull. Minist. Hlth 13, 114.Google ScholarPubMed
Davies, Joan R., Farrant, W. N. & Tomlinson, A. J. H. (1968). Further studies on the antibiotic resistance of Shigella sonnei. I. Transferable antibiotic resistance. J. Hyg., Camb. 66, 471.CrossRefGoogle ScholarPubMed
Farrant, W. N. & Tomlinson, A. J. H. (1966). Some studies on the epidemiology of Sonne dysentery. Changes in colicine type and antibiotic resistance between 1956 and 1965. J. Hyg., Camb. 64, 287.CrossRefGoogle ScholarPubMed
Lewis, M. J. (1967). Multiple transmissible drug resistance in an outbreak of Shigella flexneri infection. Lancet ii, 953.CrossRefGoogle Scholar