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Hantavirus infections in The Netherlands: epidemiology and disease

Published online by Cambridge University Press:  15 May 2009

J. Groen ,
M. N. Gerding ,
J. G. M. Jordans ,
J. P. Clement ,
J. H. M. Nieuwenhuijs  and
A. D. M. E. Osterhaus
J. Groen
Affiliation:
Centre for Exotic Virus Infections, Department of Clinical Virology, University Hospital Rotterdam, The Netherlands
M. N. Gerding
Affiliation:
Department of Internal Medicine, Medical Spectrum Twente, Enschede, The Netherlands
J. G. M. Jordans
Affiliation:
Department of Internal Medicine, Medical Spectrum Twente, Enschede, The Netherlands
J. P. Clement
Affiliation:
Queen Astrid Military Hospital, Brussels, Belgium
J. H. M. Nieuwenhuijs
Affiliation:
Veterinary Public Health Inspectorate, Rijswijk, The Netherlands
A. D. M. E. Osterhaus
Affiliation:
Centre for Exotic Virus Infections, Department of Clinical Virology, University Hospital Rotterdam, The Netherlands Institute of Virology, Erasmus University Rotterdam, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands
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A serological survey for the prevalence of hantavirus infections in The Netherlands was carried out on > 10000 sera, from selected human populations, and different feral and domestic animal species. Hantavirus-specific antibodies were found in about 1% of patients suspected of acute leptospirosis, 10% of patients with acute nephropathia, and in less than 0·1% haemodialysis and renal transplant patients. Among individuals with a suspected occupational risk, 6% of animal trappers, 4% of forestry workers, 2% of laboratory workers and 0·4% of farmers were seropositive. The majority of the seropositive individuals lived in rural and forested areas. The main animal reservoir of the infection was shown to be the red bank vole (Clethrionomys glareolus). Epidemiological, clinical and laboratory findings seen in serologically confirmed human cases were similar to those associated with nephropathia epidemica.

Type
Research Article
Information
Epidemiology & Infection , Volume 114 , Issue 2 , April 1995 , pp. 373 - 383
Copyright
Copyright © Cambridge University Press 1995

References

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