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The intra-tracheal inoculation of anthracite dust mixed with dead human tubercle bacilli into rabbits

Published online by Cambridge University Press:  15 May 2009

S. Lyle Cummins
S. Lyle Cummins
Affiliation:
Welsh National School of Medicine, Cardiff
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In 1931 Cummins, Weatherall & Waters investigated the adsorption of tuberculin by anthracite dust and the subject was further investigated by Cummins & Williams in 1938. After the publication by Kettle (1934) of his observation that the intra-tracheal inoculation of kaolin dust mixed with dead tubercle bacilli gave rise to a much greater reaction than did the inoculation of kaolin alone, the result of the mixture being comparable to an early silicotic lesion, the author, thinking that this effect might have been due to adsorption of the products of the bacilli on to the dust, tried the same experiment with a number of other dusts, met with in mines, such as those of silica, sericite and anthracite. He obtained comparable results with all of them, though of different degrees according to the dust used (Cummins, 1940b).

Type
Research Article
Information
Journal of Hygiene , Volume 41 , Issue 2 , September 1941 , pp. 101 - 104
Copyright
Copyright © Cambridge University Press 1941

References

REFERENCES

Cummins, S. L. (1940a). Augmentation of action of anthracite and other dusts by dead tubercle bapilli. Brit. J. Exp. Med. 21, 64–6.Google Scholar
Cummins, S. L. (1940b). Adsorption of the early products of bovine tubercle bacilli in rabbits by anthracite dust. Brit. Med. J. 2, 623–4.CrossRefGoogle ScholarPubMed
Cummins, S. L., Weatherall, C. & Waters, E. T. (1931). Adsorption of tuberculin by coal dust. J. Hyg., Camb., 31, 464–71.Google ScholarPubMed
Cummins, S. L. & Williams, Enid M. (1938). The adsorbent effects of various dusts on diluted ‘old’ tuberculin. J. Hyg., Camb., 38, 638–46.Google ScholarPubMed
Kettle, E. H. (1934). Experimental pneumoconiosis: infective silicatosis. J. Path. Bact. 38, 201–8.CrossRefGoogle Scholar
Sabin, F. R., Smithburn, K. C. & Thomas, R. M. (1935). Cellular reactions to wax-like materials from acid-fast bacteria. J. Exp. Path. 62, 751–69.Google ScholarPubMed