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Measurement of endotoxins with the limulus test in burned patients

Published online by Cambridge University Press:  15 May 2009

R. J. Jones  and
E. A. Roe
R. J. Jones
Affiliation:
M. R. C. Industrial Injuries and Burns Unit, Birmingham Accident Hospital, Bath Row, Birmingham B15 1NA
E. A. Roe
Affiliation:
M. R. C. Industrial Injuries and Burns Unit, Birmingham Accident Hospital, Bath Row, Birmingham B15 1NA
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Summary

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High titres of endotoxin as measured by the Limulus test were usually found in burned patients who had raised body temperatures, and were colonized with gram-negative bacteria; also some infected patients showed raised endotoxin without a raised temperature.

Patients vaccinated with an antipseudomonas vaccine rarely showed endotoxin in their plasma but occasional plasma samples from vaccinated patients had a high titre of endotoxin which appeared unrelated to infection or to a raised temperature in the patient.

Type
Research Article
Information
Journal of Hygiene , Volume 83 , Issue 1 , August 1979 , pp. 151 - 156
Copyright
Copyright © Cambridge University Press 1979

References

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