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Nosocomial klebsiellas: II. Transfer in a hospital ward

Published online by Cambridge University Press:  15 May 2009

Michael J. Haverkorn  and
M. F. Michel
Michael J. Haverkorn
Affiliation:
Department of Clinical Microbiology and Antimicrobial Therapy, Medical faculty, Erasmusuniversity, Rotterdam, The Netherlands
M. F. Michel
Affiliation:
Department of Clinical Microbiology and Antimicrobial Therapy, Medical faculty, Erasmusuniversity, Rotterdam, The Netherlands
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During a 6-month period an epidemiological survey of the carriage of Klebsiella was conducted in a hospital ward where no outbreak of nosocomial infection occurred. In this endemic situation the regular sampling of several sites on patients, members of the nursing staff, and the environment, and the biotyping of Klebsiella made it possible to analyse the patterns of transmission between sites. There was abundant evidence for striking transmission of Klebsiella between the throat, hands, and faeces of patients. Transmission between patients seemed to be mainly through hands. The role of nurses' hands in transmission was not evident from this survey, probably due to the relatively long interval (a week) between samplings. Through the hands of patients, wash stands and the surrounding floor were contaminated with Klebsiella. The biotyping of Klebsiella facilitated the epidemiological analysis of the results.

Type
Research Article
Information
Journal of Hygiene , Volume 82 , Issue 2 , April 1979 , pp. 195 - 205
Copyright
Copyright © Cambridge University Press 1979

References

REFERENCES

Burke, J. P., Ingall, D., Klein, J. O., Gezon, H. M. & Finland, M. (1971). Proteus mirabilis infection in a hospital nursery traced to a human carrier. New England Journal of Medicine 284, 115–21.Google Scholar
Casewell, M. W., Dalton, M. T., Webster, M. & Phillips, I. (1977). Gentamicin-resistant Klebsiella aerogenes in a urological ward. Lancet ii, 444–6.CrossRefGoogle Scholar
Cooke, E. M., Shooter, R. A., Kumar, P. J., Rousseau, S. A. & Foulkes, A. L. (1970). Hospital food as a possible source of Escherichia coli in patients. Lancet i, 436–7.CrossRefGoogle Scholar
Edwards, L. D., Cross, A., Levin, S. & Landau, W. (1974). Outbreak of a nosocomial infection with a strain of Proteus rettgeri resistant to many antimicrobials. American Journal of Clinical Pathology 61, 41–6.Google Scholar
Eisenach, K. D., Reber, R. M., Eitzman, D. V. & Bear, H. (1972). Nosocomial infection due to kanamycin-resistant (R)-factor carrying enteric organisms in an intensive care nursery. Pediatrics 50, 395–402.Google Scholar
Finland, M. (1970). Changing ecology of bacterial infections as related to antimicrobial therapy. Journal of Infectious Diseases 122, 419–31.Google Scholar
Fontaine, T. D. & Hoadley, A. W. (1976). Transferable drug resistance associated with coliforms isolated from hospital and domestic sewage. Health Laboratory Science 13, 238–45.Google ScholarPubMed
Grieble, H. G., Bird, T. J., Nidea, H. M. & Miller, C. A. (1974). Chute-hydropulping waste disposal system: a reservoir of enteric bacilli and Pseudomonas in a modem hospital. Journal of Infectious Diseases 130, 602–7.Google Scholar
Harvey, H. S. & Dunlop, M. B. (1960). Upper respiratory flora of husbands and wives. New England Journal of Medicine 262, 976–7.Google Scholar
Haverkorn, M. J. & Michel, M. F. (1979). Nosocomial klebsiellas. I. Colonization of hospitalized patients. Journal of Hygiene 82, 177–93.Google Scholar
Johanson, W. G., Pierse, A. K., Sanford, J. P. & Thomas, G. D. (1972). Nosocomial respiratory infections with gram-negative bacilli. The significance of colonization of the respiratory tract. Annals of Internal Medicine 77, 701–6.Google Scholar
Knittle, M. A., Eitzman, D. V. & Bear, H. (1975). Role of hand contamination of personnel in the epidemiology of gram-negative nosocomial infections. Journal of Pediatrics 86, 433–7.CrossRefGoogle ScholarPubMed
Lowbury, E. J. L., Thom, B. T., Lilly, H. A., Babb, J. R. & Whittall, K. (1970). Sources of infection with Pseudomonas aeruginosa in patients with tracheostomy. Journal of Medical Microbiology 3, 39–56.Google Scholar
Marples, R. R. (1965). The effect of hydration on the bacterial flora of the skin. In Skin Bacteria and Their Role in Infection (ed. Maibach, H. I. and Hildick-Smith, G.), pp. 33–41. New York: McGraw-Hill.Google Scholar
Marsh, P. D. & Selwyn, S. (1977). Studies on antagonism between human skin bacteria. Journal of Medical Microbiology 10, 161–9.Google Scholar
McBride, M. E., Duncan, W. C. & Knox, J. M. (1977). The environment and the microbial ecology of human skin. Applied and Environmental Microbiology 33, 603–8.Google Scholar
McGowan, J. E. & Finland, M. (1974). Infection and antibiotic usage at Boston City Hospital: Changes in prevalence during the decade 1964–1973. Journal of Infectious Diseases 129, 421–8.Google Scholar
Mendes, M. F. & Lynch, D. J. (1976). A bacteriological survey of washrooms and toilets. Journal of Hygiene 76, 183–90.Google Scholar
Noble, W. C. & Somerville, D. A. (1974). Microbiology of Human Skin, pp. 172–84. London: Saunders.Google Scholar
Petit, F. & Lowbury, E. J. L. (1968). Survival of wound pathogens under different environmental conditions. Journal of Hygiene 66, 393–406.CrossRefGoogle Scholar
Rose, H. D. & Babcock, J. B. (1975). Colonization of intensive care unit patients with gram-negative bacilli. American Journal of Epidemiology 101, 495–501.Google Scholar
Rosenthal, S. & Tager, I. B. (1975). Prevalence of gram-negative rods in the normal pharyngeal flora. Annals of Internal Medicine 83, 355–7.CrossRefGoogle ScholarPubMed
Saltzman, T. C., Clark, J. J. & Klemm, L. (1967). Hand contamination of personnel as a mechanism of cross-infection in nosocomial infections with antibiotic-resistant Escherichia coli and Klebsiella–Aerobacter. Antimicrobial Agents and Chemotherapy 7, 97–100.Google Scholar
Schaberg, D. R., Weinstein, R. A. & Stamm, W. E. (1976). Epidemics of nosocomial urinary tract infection caused by multiple resistant gram-negative bacilli: Epidemiology and control. Journal of Infectious Diseases 133, 363–6.Google Scholar
Selden, R., Lee, S., Wang, W. L. L., Bennett, J. V. & Eickhoff, T. C. (1971). Nosocomial Klebsiella infections: Intestinal colonization as a reservoir. Annals of Internal Medicine 74, 657–64.Google Scholar
Selwyn, S. & Ellis, H. (1972). Skin bacteria and skin disinfections reconsidered. British Medical Journal i, 136–40.Google Scholar
Shooter, R. A. (1971). Bowel colonization of hospital patients by Pseudomonas aeruginosa and Escherichia coli. Proceedings of the Royal lociety of Medicine 64, 989–90.Google ScholarPubMed
Sprunt, K., Redman, W. & Leily, G. (1973). Antibacterial effectiveness of routine hand washing. Pediatrics 52, 264–71.Google Scholar