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Presence of a dialysable fraction in normal bovine whey capable of killing several species of bovine mycoplasmas

Published online by Cambridge University Press:  15 May 2009

C. J. Howard ,
J. Brownlie ,
R. N. Gourlay  and
Jacqueline Collins
C. J. Howard
Affiliation:
Agricultural Research Council, Institute for Research on Animal Diseases, Compton, Newbury, Berkshire
J. Brownlie
Affiliation:
Agricultural Research Council, Institute for Research on Animal Diseases, Compton, Newbury, Berkshire
R. N. Gourlay
Affiliation:
Agricultural Research Council, Institute for Research on Animal Diseases, Compton, Newbury, Berkshire
Jacqueline Collins
Affiliation:
Agricultural Research Council, Institute for Research on Animal Diseases, Compton, Newbury, Berkshire
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Summary

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Most normal bovine whey samples contain a fraction that survives heating at 56° C. for 30 min., passes through a dialysis membrane and kills a maximum of seven out of ten of the different bovine mycoplasma species tested. Some whey samples appear more active than others but not all affect the same strains of mycoplasma indicating some specificity in their action. Absorption of the active factor from whey by heterologous and homologous mycoplasmas and by erythrocytes was observed. Binding of the factor to mycoplasmas appears to be temperature-dependent and non-specific, but subsequent mycoplasmacidal action shows some specificity.

Type
Research Article
Information
Journal of Hygiene , Volume 74 , Issue 2 , April 1975 , pp. 261 - 270
Copyright
Copyright © Cambridge University Press 1975

References

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