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Sensitivity of bluetongue virus to lipid solvents, trypsin and pH changes and its serological relationship to arboviruses*

Published online by Cambridge University Press:  15 May 2009

S.-E. Svehag ,
Louise Leendertsen  and
J. R. Gorham
S.-E. Svehag
Affiliation:
Department of Veterinary Science, Washington State University Pullman, Washington
Louise Leendertsen
Affiliation:
The Animal Disease Research Station, Animal Disease and Parasite Research Division, U.S. Department of Agriculture, Pullman, Washington
J. R. Gorham
Affiliation:
The Animal Disease Research Station, Animal Disease and Parasite Research Division, U.S. Department of Agriculture, Pullman, Washington
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Bluetongue virus was found to be resistant to ether, chloroform and sodium deoxycholate under a variety of conditions but sensitive to treatment with trypsin. The virus had a narrow zone of pH stability between pH 6 and 8 in Michaelis buffer. Below pH 6 bluetongue was irreversibly inactivated within 1 min. at 37° C. In many of its characteristics, bluetongue virus appears to be closely related to the reoviruses.

Type
Research Article
Information
Journal of Hygiene , Volume 64 , Issue 3 , September 1966 , pp. 339 - 346
Copyright
Copyright © Cambridge University Press 1966

References

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